FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310036639> ?p ?o ?g. }

• W4310036639 endingPage "4984" @default.
• W4310036639 startingPage "4984" @default.
• W4310036639 abstract "Long COVID, a condition characterized by symptom and/or sign persistence following an acute COVID-19 episode, is associated with reduced physical performance and endothelial dysfunction. Supplementation of l-arginine may improve endothelial and muscle function by stimulating nitric oxide synthesis. A single-blind randomized, placebo-controlled trial was conducted in adults aged between 20 and 60 years with persistent fatigue attending a post-acute COVID-19 outpatient clinic. Participants were randomized 1:1 to receive twice-daily orally either a combination of 1.66 g l-arginine plus 500 mg liposomal vitamin C or a placebo for 28 days. The primary outcome was the distance walked on the 6 min walk test. Secondary outcomes were handgrip strength, flow-mediated dilation, and fatigue persistence. Fifty participants were randomized to receive either l-arginine plus vitamin C or a placebo. Forty-six participants (median (interquartile range) age 51 (14), 30 [65%] women), 23 per group, received the intervention to which they were allocated and completed the study. At 28 days, l-arginine plus vitamin C increased the 6 min walk distance (+30 (40.5) m; placebo: +0 (75) m, p = 0.001) and induced a greater improvement in handgrip strength (+3.4 (7.5) kg) compared with the placebo (+1 (6.6) kg, p = 0.03). The flow-mediated dilation was greater in the active group than in the placebo (14.3% (7.3) vs. 9.4% (5.8), p = 0.03). At 28 days, fatigue was reported by two participants in the active group (8.7%) and 21 in the placebo group (80.1%; p < 0.0001). l-arginine plus vitamin C supplementation improved walking performance, muscle strength, endothelial function, and fatigue in adults with long COVID. This supplement may, therefore, be considered to restore physical performance and relieve persistent symptoms in this patient population." @default.
• W4310036639 created "2022-11-30" @default.
• W4310036639 creator A5001960093 @default.
• W4310036639 creator A5008756415 @default.
• W4310036639 creator A5023419515 @default.
• W4310036639 creator A5029502031 @default.
• W4310036639 creator A5030323904 @default.
• W4310036639 creator A5031316687 @default.
• W4310036639 creator A5038306043 @default.
• W4310036639 creator A5038563080 @default.
• W4310036639 creator A5041499982 @default.
• W4310036639 creator A5045630990 @default.
• W4310036639 creator A5045989939 @default.
• W4310036639 creator A5049412879 @default.
• W4310036639 creator A5058145026 @default.
• W4310036639 creator A5059600928 @default.
• W4310036639 creator A5060665544 @default.
• W4310036639 creator A5061789219 @default.
• W4310036639 creator A5076115568 @default.
• W4310036639 creator A5081333403 @default.
• W4310036639 creator A5085647114 @default.
• W4310036639 creator A5086564654 @default.
• W4310036639 creator A5090725835 @default.
• W4310036639 date "2022-11-23" @default.
• W4310036639 modified "2023-10-12" @default.
• W4310036639 title "Effects of l-Arginine Plus Vitamin C Supplementation on Physical Performance, Endothelial Function, and Persistent Fatigue in Adults with Long COVID: A Single-Blind Randomized Controlled Trial" @default.
• W4310036639 cites W1555489744 @default.
• W4310036639 cites W1579950305 @default.
• W4310036639 cites W1970093573 @default.
• W4310036639 cites W1974150164 @default.
• W4310036639 cites W1978285043 @default.
• W4310036639 cites W1978791759 @default.
• W4310036639 cites W1987972238 @default.
• W4310036639 cites W2023502006 @default.
• W4310036639 cites W2102839002 @default.
• W4310036639 cites W2103037586 @default.
• W4310036639 cites W2109995138 @default.
• W4310036639 cites W2112778345 @default.
• W4310036639 cites W2123263258 @default.
• W4310036639 cites W2138223428 @default.
• W4310036639 cites W2141111861 @default.
• W4310036639 cites W2152958621 @default.
• W4310036639 cites W2162716525 @default.
• W4310036639 cites W2164059021 @default.
• W4310036639 cites W2165535994 @default.
• W4310036639 cites W2166977140 @default.
• W4310036639 cites W2168898965 @default.
• W4310036639 cites W2169016202 @default.
• W4310036639 cites W2171335969 @default.
• W4310036639 cites W2244006745 @default.
• W4310036639 cites W2309975949 @default.
• W4310036639 cites W2400061768 @default.
• W4310036639 cites W2517085950 @default.
• W4310036639 cites W2747102146 @default.
• W4310036639 cites W2775825385 @default.
• W4310036639 cites W3015425399 @default.
• W4310036639 cites W3021377320 @default.
• W4310036639 cites W3022924256 @default.
• W4310036639 cites W3036960437 @default.
• W4310036639 cites W3041493976 @default.
• W4310036639 cites W3047424726 @default.
• W4310036639 cites W3047529020 @default.
• W4310036639 cites W3095857172 @default.
• W4310036639 cites W3106822009 @default.
• W4310036639 cites W3109030834 @default.
• W4310036639 cites W3117194923 @default.
• W4310036639 cites W3136352586 @default.
• W4310036639 cites W3136955306 @default.
• W4310036639 cites W3164025963 @default.
• W4310036639 cites W3164569998 @default.
• W4310036639 cites W3166260570 @default.
• W4310036639 cites W3184339862 @default.
• W4310036639 cites W3184498784 @default.
• W4310036639 cites W3191021927 @default.
• W4310036639 cites W3194737219 @default.
• W4310036639 cites W3196017671 @default.
• W4310036639 cites W3198065839 @default.
• W4310036639 cites W3206065137 @default.
• W4310036639 cites W3211702775 @default.
• W4310036639 cites W4206410324 @default.
• W4310036639 cites W4210242202 @default.
• W4310036639 cites W4213323163 @default.
• W4310036639 cites W4214867639 @default.
• W4310036639 cites W4220695110 @default.
• W4310036639 cites W4220749499 @default.
• W4310036639 cites W4220877860 @default.
• W4310036639 cites W4221013795 @default.
• W4310036639 cites W4221026046 @default.
• W4310036639 cites W4280607774 @default.
• W4310036639 cites W4281388077 @default.
• W4310036639 cites W4282822155 @default.
• W4310036639 cites W4283159427 @default.
• W4310036639 cites W4286249795 @default.
• W4310036639 cites W4287510022 @default.
• W4310036639 cites W4289886879 @default.
• W4310036639 cites W4289890883 @default.
• W4310036639 doi "https://doi.org/10.3390/nu14234984" @default.
• W4310036639 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36501014" @default.

• next