Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310105191> ?p ?o ?g. }
- W4310105191 endingPage "937" @default.
- W4310105191 startingPage "909" @default.
- W4310105191 abstract "In addition to the typical respiratory manifestations, various disorders including involvement of the nerve system have been detected in COVID-19 ranging from 22 to 36%. Although growing records are focusing on neurological aspects of COVID-19, the pathophysiological mechanisms and related therapeutic methods remain obscure. Considering the increased concerns of SARS-CoV-2 potential for more serious neuroinvasion conditions, the present review attempts to focus on the neuroprotective effects of natural compounds as the principle source of therapeutics inhibiting multiple steps of the SARS-CoV-2 infection cycle. The great majority of the natural products with anti-SARS-CoV-2 activity mainly inhibit the attachment, entry and gene expression rather than the replication, assembly, or release. Although microbial-derived natural products comprise 38.5% of the known natural products with neuroprotective effects following viral infection, the neuroprotective potential of the majority of microorganisms is still undiscovered. Among natural products, chrysin, huperzine A, ginsenoside Rg1, pterostilbene, and terrein have shown potent in vitro neuroprotective activity and can be promising for new or repurpose drugs for neurological complications of SARS-CoV-2." @default.
- W4310105191 created "2022-11-30" @default.
- W4310105191 creator A5031810848 @default.
- W4310105191 creator A5045058244 @default.
- W4310105191 creator A5049587992 @default.
- W4310105191 creator A5068777849 @default.
- W4310105191 date "2022-11-28" @default.
- W4310105191 modified "2023-10-18" @default.
- W4310105191 title "Neurological disorders of COVID-19: insights to applications of natural products from plants and microorganisms" @default.
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