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- W4310120299 abstract "Abstract Most individuals who develop tuberculosis (TB) are working-age adults living in low- and middle-income countries (LMICs). The resulting disability and death impacts economic productivity and burdens health systems. New TB vaccine candidates may reduce this burden. In this study, we estimated the impact of introducing novel TB vaccines on GDP growth in 105 LMICs, using a macroeconomic model to simulate country-level GDP trends between 2020 and 2080, in 2020 USD. We compared scenarios for introduction of infant and adolescent/adult vaccine candidates to a no-new-vaccine counterfactual. Compared to the no-new-vaccine counterfactual, both vaccination scenarios produced greater cumulative GDP in the modelled countries over the study period, equivalent to $1.6 (95% uncertainty interval: $0.8–3.0) trillion for the adolescent/adult vaccine, and $0.2 ($0.1–0.4) trillion for the infant vaccine. These GDP gains were substantially lagged relative to the time of vaccine introduction, and concentrated in countries with higher current TB incidence." @default.
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- W4310120299 date "2022-11-28" @default.
- W4310120299 modified "2023-09-29" @default.
- W4310120299 title "The potential impact of novel tuberculosis vaccine introduction on economic growth in low- and middle-income countries" @default.
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- W4310120299 doi "https://doi.org/10.1101/2022.11.23.22282690" @default.
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