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- W4310150083 abstract "Abstract Objectives The aim of this study was to establish a sheep model of the Puricelli biconvex arthroplasty (ABiP) technique in sheep for evaluation of its functional, biological and histological parameters. Materials and methods Ten Corriedale black sheep were submitted to TMJ total reconstruction with poly(methyl methacrylate) (PMMA) using ABiP and euthanized after 45 (n = 5) or 90 (n = 5) days. Control animals (n = 2) underwent sham operations and were euthanized after 45 days. Variables were assessed before the surgery (T0), immediately after (T1), and at 45 or 90 postoperative days (T2). Results Histological analyses showed regression of inflammatory cells over the follow-up period. PMMA showed reduced porosity and roughness in the articular contact area. PMMA temporal components showed linear and volumetric wear in comparison to control, but no foreign body reaction was observed. The reconstructions were stable in all animals. The amplitude of mouth opening and left lateral movements were maintained, except for a reduction in the range of right lateral movements at day 90 in the experimental group. Clinical, macroscopic and radiographic observations showed stability of the reconstructions. Conclusions The analysis of functional, biological and histological parameters in sheep submitted to ABiP showed stable results of the procedure, with maintenance of body weight and all mandibular movements, save contralateral mandibular movement, suggesting that joint function was completely maintained following the procedure. Clinical relevance This experimental study gives support to clinical results previously reported of the ABiP technique in TMJ reconstruction procedures." @default.
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- W4310150083 date "2022-11-28" @default.
- W4310150083 modified "2023-09-26" @default.
- W4310150083 title "Puricelli biconvex arthroplasty: an experimental study in sheep" @default.
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- W4310150083 doi "https://doi.org/10.21203/rs.3.rs-2278104/v1" @default.
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