Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310209091> ?p ?o ?g. }
- W4310209091 abstract "Aging and obesity are two global concerns in public health. Sarcopenic obesity (SO), defined as the combination of age-related sarcopenia and obesity, has become a pressing issue. This systematic review and meta-analysis summarize the current clinical evidence relevant to SO. PubMed, Embase, and Web of Science were searched, and 106 clinical studies with 167,151 elderlies were included. The estimated prevalence of SO was 9% in both men and women. Obesity was associated with 34% reduced risk of sarcopenia (odds ratio [OR] 0.66, 95% CI 0.48-0.91; p < 0.001). The pooled hazard ratio (HR) of all-cause mortality was 1.51 (95% CI 1.14-2.02; p < 0.001) for people with SO compared with healthy individuals. SO was associated with increased risk of cardiovascular disease and related mortality, metabolic disorders, cognitive impairment, arthritis, functional limitation, and lung diseases (all ORs > 1.0, p < 0.05). The attenuated risk of sarcopenia in elderlies with obesity (obesity paradox) was dependent on higher muscle mass and strength. Apart from unifying the diagnosis of SO, more research is needed to subphenotype people with obesity and sarcopenia for individualized treatment. Meanwhile, the maintenance of proper body composition of muscle and fat may delay or attenuate the adverse outcomes of aging." @default.
- W4310209091 created "2022-11-30" @default.
- W4310209091 creator A5018015203 @default.
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- W4310209091 creator A5089998778 @default.
- W4310209091 date "2022-11-28" @default.
- W4310209091 modified "2023-10-16" @default.
- W4310209091 title "Deciphering the “obesity paradox” in the elderly: A systematic review and meta‐analysis of sarcopenic obesity" @default.
- W4310209091 cites W1777399276 @default.
- W4310209091 cites W1783146529 @default.
- W4310209091 cites W1893373802 @default.
- W4310209091 cites W1905520651 @default.
- W4310209091 cites W1971268803 @default.
- W4310209091 cites W1986987962 @default.
- W4310209091 cites W1998007271 @default.
- W4310209091 cites W1999181657 @default.
- W4310209091 cites W2002377266 @default.
- W4310209091 cites W2012034845 @default.
- W4310209091 cites W2017264236 @default.
- W4310209091 cites W2028886777 @default.
- W4310209091 cites W2042456631 @default.
- W4310209091 cites W2053329933 @default.
- W4310209091 cites W2055418044 @default.
- W4310209091 cites W2057527999 @default.
- W4310209091 cites W2064406350 @default.
- W4310209091 cites W2067397016 @default.
- W4310209091 cites W2068652792 @default.
- W4310209091 cites W2069544473 @default.
- W4310209091 cites W2070140621 @default.
- W4310209091 cites W2071665447 @default.
- W4310209091 cites W2076262699 @default.
- W4310209091 cites W2083683145 @default.
- W4310209091 cites W2084593475 @default.
- W4310209091 cites W2087177011 @default.
- W4310209091 cites W2087540908 @default.
- W4310209091 cites W2089391730 @default.
- W4310209091 cites W2090986073 @default.
- W4310209091 cites W2093755531 @default.
- W4310209091 cites W2102902846 @default.
- W4310209091 cites W2103784531 @default.
- W4310209091 cites W2106641809 @default.
- W4310209091 cites W2107549333 @default.
- W4310209091 cites W2115764491 @default.
- W4310209091 cites W2119027356 @default.
- W4310209091 cites W2122540540 @default.
- W4310209091 cites W2122546156 @default.
- W4310209091 cites W2124679472 @default.
- W4310209091 cites W2132273917 @default.
- W4310209091 cites W2132449055 @default.
- W4310209091 cites W2133196083 @default.
- W4310209091 cites W2147207008 @default.
- W4310209091 cites W2147962028 @default.
- W4310209091 cites W2151930815 @default.
- W4310209091 cites W2156791190 @default.
- W4310209091 cites W2162321723 @default.
- W4310209091 cites W2164728502 @default.
- W4310209091 cites W2217016020 @default.
- W4310209091 cites W2264990363 @default.
- W4310209091 cites W2288815822 @default.
- W4310209091 cites W2297738515 @default.
- W4310209091 cites W2298312434 @default.
- W4310209091 cites W2307246836 @default.
- W4310209091 cites W2314852100 @default.
- W4310209091 cites W2339635261 @default.
- W4310209091 cites W2465905192 @default.
- W4310209091 cites W2470343227 @default.
- W4310209091 cites W2520463455 @default.
- W4310209091 cites W2530050540 @default.
- W4310209091 cites W2544144113 @default.
- W4310209091 cites W2561422649 @default.
- W4310209091 cites W2588775722 @default.
- W4310209091 cites W2590068197 @default.
- W4310209091 cites W2590896429 @default.
- W4310209091 cites W2614428059 @default.
- W4310209091 cites W2618104922 @default.
- W4310209091 cites W2723578287 @default.
- W4310209091 cites W2727627814 @default.
- W4310209091 cites W2734380231 @default.
- W4310209091 cites W2772887716 @default.
- W4310209091 cites W2775087469 @default.
- W4310209091 cites W2796563472 @default.
- W4310209091 cites W2801919427 @default.
- W4310209091 cites W2810529814 @default.
- W4310209091 cites W2889107397 @default.
- W4310209091 cites W2890576171 @default.
- W4310209091 cites W2894625288 @default.
- W4310209091 cites W2895679601 @default.
- W4310209091 cites W2897513125 @default.
- W4310209091 cites W2900569871 @default.
- W4310209091 cites W2929558065 @default.
- W4310209091 cites W2931720783 @default.
- W4310209091 cites W2940158243 @default.
- W4310209091 cites W2943555410 @default.
- W4310209091 cites W2947519079 @default.
- W4310209091 cites W2951738572 @default.