Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310249105> ?p ?o ?g. }
- W4310249105 endingPage "135075" @default.
- W4310249105 startingPage "135075" @default.
- W4310249105 abstract "Profilin family members are potential pan-allergens in foods, presenting public health hazards. However, studies on the allergenicity modification of profilin allergens are limited. Herein, quercetin and its glycosides (isoquercitrin and rutin) were applied to modify the allergenicity of a profilin allergen (Bra c p) from Brassica campestris bee pollen. Results showed that only quercetin can be closely covalently bound to Bra c p among the three, and the binding site was located at the Cys98 residue. After covalently conjunction, the relative content of α-helix structure in Bra c p was reduced by 40.05%, while random coil was increased by 42.89%; moreover, the Tyr and Phe residues in Bra c p were masked. These structural changes could alter the conformational antigenic epitopes of Bra c p, resulting in its allergenicity reduction. Our findings might provide a technical foundation for reducing the allergenicity of bee pollen and foods containing profilin family allergens." @default.
- W4310249105 created "2022-11-30" @default.
- W4310249105 creator A5050534994 @default.
- W4310249105 creator A5053310295 @default.
- W4310249105 creator A5078536854 @default.
- W4310249105 creator A5080001956 @default.
- W4310249105 creator A5085670661 @default.
- W4310249105 creator A5086490578 @default.
- W4310249105 date "2023-04-01" @default.
- W4310249105 modified "2023-09-23" @default.
- W4310249105 title "Effects of covalent conjugation with quercetin and its glycosides on the structure and allergenicity of Bra c p from bee pollen" @default.
- W4310249105 cites W1997309243 @default.
- W4310249105 cites W2008630616 @default.
- W4310249105 cites W2013521007 @default.
- W4310249105 cites W2020538616 @default.
- W4310249105 cites W2023037761 @default.
- W4310249105 cites W2036355484 @default.
- W4310249105 cites W2086874328 @default.
- W4310249105 cites W2139567393 @default.
- W4310249105 cites W2148793204 @default.
- W4310249105 cites W2741128197 @default.
- W4310249105 cites W2768426278 @default.
- W4310249105 cites W2794319698 @default.
- W4310249105 cites W2809210315 @default.
- W4310249105 cites W2887106624 @default.
- W4310249105 cites W2889246958 @default.
- W4310249105 cites W2889948383 @default.
- W4310249105 cites W2890935365 @default.
- W4310249105 cites W2893097826 @default.
- W4310249105 cites W2908956069 @default.
- W4310249105 cites W2924930352 @default.
- W4310249105 cites W2966556696 @default.
- W4310249105 cites W3012370450 @default.
- W4310249105 cites W3024903566 @default.
- W4310249105 cites W3026987762 @default.
- W4310249105 cites W3036825944 @default.
- W4310249105 cites W3091854037 @default.
- W4310249105 cites W3094249419 @default.
- W4310249105 cites W3117382094 @default.
- W4310249105 cites W3128392560 @default.
- W4310249105 cites W3181212969 @default.
- W4310249105 cites W3210982317 @default.
- W4310249105 cites W4224988911 @default.
- W4310249105 cites W4283447321 @default.
- W4310249105 doi "https://doi.org/10.1016/j.foodchem.2022.135075" @default.
- W4310249105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36462363" @default.
- W4310249105 hasPublicationYear "2023" @default.
- W4310249105 type Work @default.
- W4310249105 citedByCount "2" @default.
- W4310249105 countsByYear W43102491052023 @default.
- W4310249105 crossrefType "journal-article" @default.
- W4310249105 hasAuthorship W4310249105A5050534994 @default.
- W4310249105 hasAuthorship W4310249105A5053310295 @default.
- W4310249105 hasAuthorship W4310249105A5078536854 @default.
- W4310249105 hasAuthorship W4310249105A5080001956 @default.
- W4310249105 hasAuthorship W4310249105A5085670661 @default.
- W4310249105 hasAuthorship W4310249105A5086490578 @default.
- W4310249105 hasConcept C142669718 @default.
- W4310249105 hasConcept C1491633281 @default.
- W4310249105 hasConcept C185592680 @default.
- W4310249105 hasConcept C194671627 @default.
- W4310249105 hasConcept C203014093 @default.
- W4310249105 hasConcept C203253989 @default.
- W4310249105 hasConcept C207480886 @default.
- W4310249105 hasConcept C2775963812 @default.
- W4310249105 hasConcept C2778004101 @default.
- W4310249105 hasConcept C2780510475 @default.
- W4310249105 hasConcept C2780618852 @default.
- W4310249105 hasConcept C2781263971 @default.
- W4310249105 hasConcept C2781338088 @default.
- W4310249105 hasConcept C2993400109 @default.
- W4310249105 hasConcept C31903555 @default.
- W4310249105 hasConcept C55493867 @default.
- W4310249105 hasConcept C59822182 @default.
- W4310249105 hasConcept C71240020 @default.
- W4310249105 hasConcept C86803240 @default.
- W4310249105 hasConceptScore W4310249105C142669718 @default.
- W4310249105 hasConceptScore W4310249105C1491633281 @default.
- W4310249105 hasConceptScore W4310249105C185592680 @default.
- W4310249105 hasConceptScore W4310249105C194671627 @default.
- W4310249105 hasConceptScore W4310249105C203014093 @default.
- W4310249105 hasConceptScore W4310249105C203253989 @default.
- W4310249105 hasConceptScore W4310249105C207480886 @default.
- W4310249105 hasConceptScore W4310249105C2775963812 @default.
- W4310249105 hasConceptScore W4310249105C2778004101 @default.
- W4310249105 hasConceptScore W4310249105C2780510475 @default.
- W4310249105 hasConceptScore W4310249105C2780618852 @default.
- W4310249105 hasConceptScore W4310249105C2781263971 @default.
- W4310249105 hasConceptScore W4310249105C2781338088 @default.
- W4310249105 hasConceptScore W4310249105C2993400109 @default.
- W4310249105 hasConceptScore W4310249105C31903555 @default.
- W4310249105 hasConceptScore W4310249105C55493867 @default.
- W4310249105 hasConceptScore W4310249105C59822182 @default.
- W4310249105 hasConceptScore W4310249105C71240020 @default.
- W4310249105 hasConceptScore W4310249105C86803240 @default.
- W4310249105 hasFunder F4320321001 @default.
- W4310249105 hasFunder F4320335848 @default.
- W4310249105 hasLocation W43102491051 @default.