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• W4310251710 startingPage "864" @default.
• W4310251710 abstract "The application of synthetic biology approaches to study development opens the possibility to build and manipulate developmental processes to understand them better. Researchers have reconstituted fundamental developmental processes, such as cell patterning and sorting, by engineering gene circuits in vitro. Moreover, new tools have been created that allow for the control of developmental processes in more complex organoids and embryos. Synthetic approaches allow testing of which components are sufficient to reproduce a developmental process and under which conditions as well as what effect perturbations have on other processes. We envision that the future of synthetic developmental biology requires an increase in the diversity of available tools and further efforts to combine multiple developmental processes into one system." @default.
• W4310251710 created "2022-11-30" @default.
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• W4310251710 date "2022-11-25" @default.
• W4310251710 modified "2023-10-03" @default.
• W4310251710 title "Scaling up complexity in synthetic developmental biology" @default.
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• W4310251710 doi "https://doi.org/10.1126/science.add9666" @default.
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