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- W4310251912 abstract "Immune cells are being engineered to recognize and respond to disease states, acting as a living drug when transferred into patients. Therapies based on engineered immune cells are now a clinical reality, with multiple engineered T cell therapies approved for treatment of hematologic malignancies. Ongoing preclinical and clinical studies are testing diverse strategies to modify the fate and function of immune cells for applications in cancer, infectious disease, and beyond. Here, we discuss current progress in treating human disease with immune cell therapeutics, emerging strategies for immune cell engineering, and challenges facing the field, with a particular emphasis on the treatment of cancer, where the most effort has been applied to date." @default.
- W4310251912 created "2022-11-30" @default.
- W4310251912 creator A5001336137 @default.
- W4310251912 creator A5015981980 @default.
- W4310251912 creator A5029763484 @default.
- W4310251912 creator A5087926553 @default.
- W4310251912 date "2022-11-25" @default.
- W4310251912 modified "2023-09-28" @default.
- W4310251912 title "The future of engineered immune cell therapies" @default.
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- W4310251912 doi "https://doi.org/10.1126/science.abq6990" @default.
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- W4310251912 hasPublicationYear "2022" @default.
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