Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310253622> ?p ?o ?g. }
- W4310253622 endingPage "114182" @default.
- W4310253622 startingPage "114182" @default.
- W4310253622 abstract "Melatonin potentially regulates the female animal reproductive function, but its regulatory mechanism in the apoptosis of sheep endometrial epithelial cells (SEECs) remains to be elucidated. In the present study, immunofluorescence staining, western blotting, and quantitative real-time polymerase chain reaction were performed to detect the distribution of melatonin receptors (MT1 and MT2) in the uterus of sheep and the effect of melatonin via the receptor and non-receptor pathways on the apoptosis of SEECs in vitro. The results showed that melatonin inhibits the apoptosis of SEECs to varying degrees to regulate the expression of estrogen receptors (ERs) and progesterone receptors (PGR) via its interaction with MT1 and MT2. In addition, the ER antagonist partially relieved the inhibitory effect of melatonin on the apoptosis of SEECs, while the PGR antagonist did not. Thus, melatonin mediates endometrial epithelial apoptosis through the MT receptors and also by regulating estrogen function. This study provides evidence of the regulatory mechanism of melatonin on the physiological function of the sheep uterus." @default.
- W4310253622 created "2022-11-30" @default.
- W4310253622 creator A5002426571 @default.
- W4310253622 creator A5004178707 @default.
- W4310253622 creator A5012085095 @default.
- W4310253622 creator A5031139012 @default.
- W4310253622 creator A5051788465 @default.
- W4310253622 creator A5062494554 @default.
- W4310253622 creator A5062874377 @default.
- W4310253622 creator A5064222660 @default.
- W4310253622 creator A5083569396 @default.
- W4310253622 date "2023-03-01" @default.
- W4310253622 modified "2023-09-24" @default.
- W4310253622 title "The effect of melatonin on sheep endometrial epithelial cell apoptosis through the receptor and non-receptor pathways" @default.
- W4310253622 cites W1962964894 @default.
- W4310253622 cites W1990903820 @default.
- W4310253622 cites W1991448134 @default.
- W4310253622 cites W1993995621 @default.
- W4310253622 cites W2011590093 @default.
- W4310253622 cites W2012688719 @default.
- W4310253622 cites W2016494762 @default.
- W4310253622 cites W2028140879 @default.
- W4310253622 cites W2035203529 @default.
- W4310253622 cites W2035602883 @default.
- W4310253622 cites W2039596731 @default.
- W4310253622 cites W2046867627 @default.
- W4310253622 cites W2047511773 @default.
- W4310253622 cites W2056242053 @default.
- W4310253622 cites W2064284579 @default.
- W4310253622 cites W2073622913 @default.
- W4310253622 cites W2075892677 @default.
- W4310253622 cites W2103490973 @default.
- W4310253622 cites W2107668207 @default.
- W4310253622 cites W2114256210 @default.
- W4310253622 cites W2131454266 @default.
- W4310253622 cites W2134979684 @default.
- W4310253622 cites W2139360111 @default.
- W4310253622 cites W2145873054 @default.
- W4310253622 cites W2151281403 @default.
- W4310253622 cites W2320101893 @default.
- W4310253622 cites W2394493039 @default.
- W4310253622 cites W2598085949 @default.
- W4310253622 cites W2790892321 @default.
- W4310253622 cites W2791250252 @default.
- W4310253622 cites W2793456198 @default.
- W4310253622 cites W2811408547 @default.
- W4310253622 cites W2891078833 @default.
- W4310253622 cites W2911348880 @default.
- W4310253622 cites W2972175994 @default.
- W4310253622 cites W2993119172 @default.
- W4310253622 cites W3010088053 @default.
- W4310253622 cites W3017174778 @default.
- W4310253622 cites W3021968261 @default.
- W4310253622 cites W3022708758 @default.
- W4310253622 cites W3026757122 @default.
- W4310253622 cites W3041064744 @default.
- W4310253622 cites W3090350521 @default.
- W4310253622 cites W3091854904 @default.
- W4310253622 cites W3093758706 @default.
- W4310253622 cites W3093778216 @default.
- W4310253622 cites W3104116820 @default.
- W4310253622 cites W3119220635 @default.
- W4310253622 cites W3128416674 @default.
- W4310253622 cites W800975637 @default.
- W4310253622 doi "https://doi.org/10.1016/j.ygcen.2022.114182" @default.
- W4310253622 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36455642" @default.
- W4310253622 hasPublicationYear "2023" @default.
- W4310253622 type Work @default.
- W4310253622 citedByCount "1" @default.
- W4310253622 countsByYear W43102536222023 @default.
- W4310253622 crossrefType "journal-article" @default.
- W4310253622 hasAuthorship W4310253622A5002426571 @default.
- W4310253622 hasAuthorship W4310253622A5004178707 @default.
- W4310253622 hasAuthorship W4310253622A5012085095 @default.
- W4310253622 hasAuthorship W4310253622A5031139012 @default.
- W4310253622 hasAuthorship W4310253622A5051788465 @default.
- W4310253622 hasAuthorship W4310253622A5062494554 @default.
- W4310253622 hasAuthorship W4310253622A5062874377 @default.
- W4310253622 hasAuthorship W4310253622A5064222660 @default.
- W4310253622 hasAuthorship W4310253622A5083569396 @default.
- W4310253622 hasConcept C121608353 @default.
- W4310253622 hasConcept C126322002 @default.
- W4310253622 hasConcept C134018914 @default.
- W4310253622 hasConcept C170493617 @default.
- W4310253622 hasConcept C190283241 @default.
- W4310253622 hasConcept C2777164284 @default.
- W4310253622 hasConcept C2778182776 @default.
- W4310253622 hasConcept C2781269140 @default.
- W4310253622 hasConcept C530470458 @default.
- W4310253622 hasConcept C54355233 @default.
- W4310253622 hasConcept C55493867 @default.
- W4310253622 hasConcept C62478195 @default.
- W4310253622 hasConcept C71924100 @default.
- W4310253622 hasConcept C84606932 @default.
- W4310253622 hasConcept C86803240 @default.
- W4310253622 hasConcept C95444343 @default.
- W4310253622 hasConceptScore W4310253622C121608353 @default.
- W4310253622 hasConceptScore W4310253622C126322002 @default.