Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310262056> ?p ?o ?g. }
- W4310262056 abstract "The risk of cardiovascular disease (CVD) in diabetes mellitus (DM) patients is two- to three-fold higher than in the general population. We designed a 10-year cohort trial in T2DM patients to explore the performance of QRESEARCH risk estimator version 3 (QRISK3) as a CVD risk assessment tool and compared to Framingham Risk Score (FRS).This is a single-center analysis of prospective data collected from 566 newly-diagnosed patients with type 2 DM (T2DM). The risk scores were compared to CVD development in patients with and without CVD. The risk variables of CVD were identified using univariate analysis and multivariate cox regression analysis. The number of patients classified as low risk (<10%), intermediate risk (10%-20%), and high risk (>20%) for two tools were identified and compared, as well as their sensitivity, specificity, positive and negative predictive values, and consistency (C) statistics analysis.Among the 566 individuals identified in our cohort, there were 138 (24.4%) CVD episodes. QRISK3 classified most CVD patients as high risk, with 91 (65.9%) patients. QRISK3 had a high sensitivity of 91.3% on a 10% cut-off dichotomy, but a higher specificity of 90.7% on a 20% cut-off dichotomy. With a 10% cut-off dichotomy, FRS had a higher specificity of 89.1%, but a higher sensitivity of 80.1% on a 20% cut-off dichotomy. Regardless of the cut-off dichotomy approach, the C-statistics of QRISK3 were higher than those of FRS.QRISK3 comprehensively and accurately predicted the risk of CVD events in T2DM patients, superior to FRS. In the future, we need to conduct a large-scale T2DM cohort study to verify further the ability of QRISK3 to predict CVD events." @default.
- W4310262056 created "2022-11-30" @default.
- W4310262056 creator A5024611619 @default.
- W4310262056 creator A5058884484 @default.
- W4310262056 creator A5059975583 @default.
- W4310262056 creator A5060348530 @default.
- W4310262056 creator A5082681554 @default.
- W4310262056 date "2022-11-28" @default.
- W4310262056 modified "2023-10-18" @default.
- W4310262056 title "Assessment of QRISK3 as a predictor of cardiovascular disease events in type 2 diabetes mellitus" @default.
- W4310262056 cites W2073887351 @default.
- W4310262056 cites W2126919962 @default.
- W4310262056 cites W2139330607 @default.
- W4310262056 cites W2147663252 @default.
- W4310262056 cites W2148092884 @default.
- W4310262056 cites W2399385044 @default.
- W4310262056 cites W2618596952 @default.
- W4310262056 cites W2786822873 @default.
- W4310262056 cites W2908561509 @default.
- W4310262056 cites W2920321379 @default.
- W4310262056 cites W2950713237 @default.
- W4310262056 cites W2953059279 @default.
- W4310262056 cites W2983452894 @default.
- W4310262056 cites W2990784972 @default.
- W4310262056 cites W3005741169 @default.
- W4310262056 cites W3009495010 @default.
- W4310262056 cites W3019259851 @default.
- W4310262056 cites W3020528808 @default.
- W4310262056 cites W3024085885 @default.
- W4310262056 cites W3034654984 @default.
- W4310262056 cites W3093540699 @default.
- W4310262056 cites W3109675921 @default.
- W4310262056 cites W3147389358 @default.
- W4310262056 cites W3164908522 @default.
- W4310262056 cites W3178179639 @default.
- W4310262056 cites W3217415110 @default.
- W4310262056 cites W4205984198 @default.
- W4310262056 cites W4224123008 @default.
- W4310262056 cites W4225368577 @default.
- W4310262056 cites W4254631170 @default.
- W4310262056 cites W4281675919 @default.
- W4310262056 cites W4292749593 @default.
- W4310262056 cites W4293027689 @default.
- W4310262056 doi "https://doi.org/10.3389/fendo.2022.1077632" @default.
- W4310262056 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36518244" @default.
- W4310262056 hasPublicationYear "2022" @default.
- W4310262056 type Work @default.
- W4310262056 citedByCount "1" @default.
- W4310262056 countsByYear W43102620562023 @default.
- W4310262056 crossrefType "journal-article" @default.
- W4310262056 hasAuthorship W4310262056A5024611619 @default.
- W4310262056 hasAuthorship W4310262056A5058884484 @default.
- W4310262056 hasAuthorship W4310262056A5059975583 @default.
- W4310262056 hasAuthorship W4310262056A5060348530 @default.
- W4310262056 hasAuthorship W4310262056A5082681554 @default.
- W4310262056 hasBestOaLocation W43102620561 @default.
- W4310262056 hasConcept C105795698 @default.
- W4310262056 hasConcept C11783203 @default.
- W4310262056 hasConcept C12174686 @default.
- W4310262056 hasConcept C126322002 @default.
- W4310262056 hasConcept C134018914 @default.
- W4310262056 hasConcept C144301174 @default.
- W4310262056 hasConcept C161584116 @default.
- W4310262056 hasConcept C188816634 @default.
- W4310262056 hasConcept C199163554 @default.
- W4310262056 hasConcept C2779134260 @default.
- W4310262056 hasConcept C2908647359 @default.
- W4310262056 hasConcept C2910068830 @default.
- W4310262056 hasConcept C33923547 @default.
- W4310262056 hasConcept C38180746 @default.
- W4310262056 hasConcept C38652104 @default.
- W4310262056 hasConcept C41008148 @default.
- W4310262056 hasConcept C555293320 @default.
- W4310262056 hasConcept C71924100 @default.
- W4310262056 hasConcept C72563966 @default.
- W4310262056 hasConcept C99454951 @default.
- W4310262056 hasConceptScore W4310262056C105795698 @default.
- W4310262056 hasConceptScore W4310262056C11783203 @default.
- W4310262056 hasConceptScore W4310262056C12174686 @default.
- W4310262056 hasConceptScore W4310262056C126322002 @default.
- W4310262056 hasConceptScore W4310262056C134018914 @default.
- W4310262056 hasConceptScore W4310262056C144301174 @default.
- W4310262056 hasConceptScore W4310262056C161584116 @default.
- W4310262056 hasConceptScore W4310262056C188816634 @default.
- W4310262056 hasConceptScore W4310262056C199163554 @default.
- W4310262056 hasConceptScore W4310262056C2779134260 @default.
- W4310262056 hasConceptScore W4310262056C2908647359 @default.
- W4310262056 hasConceptScore W4310262056C2910068830 @default.
- W4310262056 hasConceptScore W4310262056C33923547 @default.
- W4310262056 hasConceptScore W4310262056C38180746 @default.
- W4310262056 hasConceptScore W4310262056C38652104 @default.
- W4310262056 hasConceptScore W4310262056C41008148 @default.
- W4310262056 hasConceptScore W4310262056C555293320 @default.
- W4310262056 hasConceptScore W4310262056C71924100 @default.
- W4310262056 hasConceptScore W4310262056C72563966 @default.
- W4310262056 hasConceptScore W4310262056C99454951 @default.
- W4310262056 hasFunder F4320321001 @default.
- W4310262056 hasFunder F4320324176 @default.
- W4310262056 hasLocation W43102620561 @default.
- W4310262056 hasLocation W43102620562 @default.