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- W4310288509 abstract "In this paper, we disclosed a novel enantioselective total synthesis of spirotryprostatin A (1) in 15 steps with a 7.4% total yield from commercially available 2-iodo-5-methoxyaniline and γ-butyrolactone. The key step features of this synthesis include the copper-catalyzed cascade reaction of o-iodoaniline derivatives with alkynone to introduce the quaternary carbon stereocenter and an aza-Michael tandem reaction to construct the spiro[pyrrolidine-3,3′-oxindole] moiety." @default.
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- W4310288509 date "2022-11-29" @default.
- W4310288509 modified "2023-10-17" @default.
- W4310288509 title "Enantioselective Total Synthesis of Spirotryprostatin A" @default.
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- W4310288509 doi "https://doi.org/10.1021/acs.joc.2c02391" @default.
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