Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310299392> ?p ?o ?g. }
- W4310299392 abstract "Abstract Olfaction, as one of our 5 senses, plays an important role in our daily lives. It is connected to proper nutrition, social interaction, and protection mechanisms. Disorders affecting this sense consequently also affect the patients’ general quality of life. Because the underlying genetics of congenital olfactory disorders (COD) have not been thoroughly investigated yet, this systematic review aimed at providing information on genes that have previously been reported to be mutated in patients suffering from COD. This was achieved by systematically reviewing existing literature on 3 databases, namely PubMed, Ovid Medline, and ISI Web of Science. Genes and the type of disorder, that is, isolated and/or syndromic COD were included in this study, as were the patients’ associated abnormal features, which were categorized according to the affected organ(-system). Our research yielded 82 candidate genes/chromosome loci for isolated and/or syndromic COD. Our results revealed that the majority of these are implicated in syndromic COD, a few accounted for syndromic and isolated COD, and the least underly isolated COD. Most commonly, structures of the central nervous system displayed abnormalities. This study is meant to assist clinicians in determining the type of COD and detecting potentially abnormal features in patients with confirmed genetic variations. Future research will hopefully expand this list and thereby further improve our understanding of COD." @default.
- W4310299392 created "2022-11-30" @default.
- W4310299392 creator A5007537300 @default.
- W4310299392 creator A5031208783 @default.
- W4310299392 creator A5087200295 @default.
- W4310299392 creator A5089900323 @default.
- W4310299392 date "2022-01-01" @default.
- W4310299392 modified "2023-10-16" @default.
- W4310299392 title "Genetics of congenital olfactory dysfunction: a systematic review of the literature" @default.
- W4310299392 cites W1492144011 @default.
- W4310299392 cites W1577166581 @default.
- W4310299392 cites W1599065016 @default.
- W4310299392 cites W1836227762 @default.
- W4310299392 cites W1884027425 @default.
- W4310299392 cites W1912624095 @default.
- W4310299392 cites W1933799138 @default.
- W4310299392 cites W1964741660 @default.
- W4310299392 cites W1967147932 @default.
- W4310299392 cites W1968277318 @default.
- W4310299392 cites W1969476971 @default.
- W4310299392 cites W1974404616 @default.
- W4310299392 cites W1980056733 @default.
- W4310299392 cites W1980311612 @default.
- W4310299392 cites W1981510039 @default.
- W4310299392 cites W1982199134 @default.
- W4310299392 cites W1982722861 @default.
- W4310299392 cites W1983575054 @default.
- W4310299392 cites W1984996843 @default.
- W4310299392 cites W1992354899 @default.
- W4310299392 cites W1996577702 @default.
- W4310299392 cites W1996915363 @default.
- W4310299392 cites W1997512315 @default.
- W4310299392 cites W1999911866 @default.
- W4310299392 cites W1999912381 @default.
- W4310299392 cites W2002151997 @default.
- W4310299392 cites W2003282533 @default.
- W4310299392 cites W2005412082 @default.
- W4310299392 cites W2005669202 @default.
- W4310299392 cites W2006217510 @default.
- W4310299392 cites W2006255591 @default.
- W4310299392 cites W2009045981 @default.
- W4310299392 cites W2010093407 @default.
- W4310299392 cites W2010330290 @default.
- W4310299392 cites W2011817955 @default.
- W4310299392 cites W2013266922 @default.
- W4310299392 cites W2013806256 @default.
- W4310299392 cites W2015550335 @default.
- W4310299392 cites W2017503582 @default.
- W4310299392 cites W2018348038 @default.
- W4310299392 cites W2019614876 @default.
- W4310299392 cites W2020101887 @default.
- W4310299392 cites W2022958390 @default.
- W4310299392 cites W2023131602 @default.
- W4310299392 cites W2024155454 @default.
- W4310299392 cites W2024319790 @default.
- W4310299392 cites W2025161059 @default.
- W4310299392 cites W2026075483 @default.
- W4310299392 cites W2027617265 @default.
- W4310299392 cites W2027829589 @default.
- W4310299392 cites W2028962442 @default.
- W4310299392 cites W2033704589 @default.
- W4310299392 cites W2035103687 @default.
- W4310299392 cites W2037168974 @default.
- W4310299392 cites W2037624480 @default.
- W4310299392 cites W2040183641 @default.
- W4310299392 cites W2045861994 @default.
- W4310299392 cites W2046621199 @default.
- W4310299392 cites W2049378924 @default.
- W4310299392 cites W2050025620 @default.
- W4310299392 cites W2050681029 @default.
- W4310299392 cites W2051852931 @default.
- W4310299392 cites W2052940896 @default.
- W4310299392 cites W2055633353 @default.
- W4310299392 cites W2056919029 @default.
- W4310299392 cites W2058482858 @default.
- W4310299392 cites W2061867414 @default.
- W4310299392 cites W2062910296 @default.
- W4310299392 cites W2063675487 @default.
- W4310299392 cites W2065094204 @default.
- W4310299392 cites W2065461957 @default.
- W4310299392 cites W2067065427 @default.
- W4310299392 cites W2067244055 @default.
- W4310299392 cites W2067265604 @default.
- W4310299392 cites W2067422295 @default.
- W4310299392 cites W2068053473 @default.
- W4310299392 cites W2077166158 @default.
- W4310299392 cites W2078473800 @default.
- W4310299392 cites W2079455457 @default.
- W4310299392 cites W2083013016 @default.
- W4310299392 cites W2090831400 @default.
- W4310299392 cites W2091247660 @default.
- W4310299392 cites W2094818113 @default.
- W4310299392 cites W2096184116 @default.
- W4310299392 cites W2098762562 @default.
- W4310299392 cites W2099918680 @default.
- W4310299392 cites W2101121629 @default.
- W4310299392 cites W2103673724 @default.
- W4310299392 cites W2108652707 @default.
- W4310299392 cites W2109621861 @default.
- W4310299392 cites W2115163299 @default.