Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310335721> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4310335721 endingPage "698" @default.
- W4310335721 startingPage "693" @default.
- W4310335721 abstract "Immune checkpoint molecules have critical roles in directing immune responses into co-inhibitory and co-stimulatory signals. Herpes virus entry mediator (HVEM) is a receptor of tumor necrosis factor receptor superfamily with unique features due to its interaction with both inhibitory and stimulatory ligands. The aim of this study was to measure the serum level of the soluble form of HVEM in patients with gastric, colorectal and breast cancers and evaluating its diagnostic and prognostic value.The concentration of the soluble HVEM (sHVEM) was determined in the serum of 36 patients with breast cancer, 50 patients with colorectal cancer and 59 patients with gastric cancer using ELISA method. Moreover, 50 healthy donors (HD) as well as 31 patients with non-ulcer dyspepsia (NUD) were used as control groups. The patients' samples were obtained from the Biobank of Cancer Research Center, Mazandaran University of Medical Sciences, Sari, Iran.The level of sHVEM was significantly higher in patients with gastric (P=0.001) and breast cancer (P=0.01) than in control groups (HD). The higher level of sHVEM was observed in colorectal cancer patients in comparison with HD group, although it was not significant. Moreover, the elevated level of sHVEM was shown to be higher significantly in stage III and IV compared to stage I and II in breast cancer (P=0.03). Similar finding was detected in gastric and colorectal cancers, but not to be statistically significant.The results of the present study suggest that the serum level of sHVEM may be considered as a promising indicator for diagnosis as well as evaluating the progression of cancers such as gastric, breast and colorectal cancers." @default.
- W4310335721 created "2022-12-08" @default.
- W4310335721 creator A5017632255 @default.
- W4310335721 creator A5020164418 @default.
- W4310335721 creator A5032872851 @default.
- W4310335721 creator A5037059208 @default.
- W4310335721 creator A5042651976 @default.
- W4310335721 creator A5060553992 @default.
- W4310335721 creator A5071197619 @default.
- W4310335721 creator A5082471003 @default.
- W4310335721 creator A5015824657 @default.
- W4310335721 date "2022-01-01" @default.
- W4310335721 modified "2023-10-16" @default.
- W4310335721 title "Can we consider soluble herpes virus entry mediator (sHVEM) as a tumor marker?" @default.
- W4310335721 cites W1584609775 @default.
- W4310335721 cites W1889506817 @default.
- W4310335721 cites W1975281374 @default.
- W4310335721 cites W1999449285 @default.
- W4310335721 cites W2022216088 @default.
- W4310335721 cites W2030612376 @default.
- W4310335721 cites W2077455977 @default.
- W4310335721 cites W2084659308 @default.
- W4310335721 cites W2119064369 @default.
- W4310335721 cites W2134667174 @default.
- W4310335721 cites W2158523429 @default.
- W4310335721 cites W2164575383 @default.
- W4310335721 cites W2166590009 @default.
- W4310335721 cites W2499398576 @default.
- W4310335721 cites W2561052156 @default.
- W4310335721 cites W2588504055 @default.
- W4310335721 cites W2626453090 @default.
- W4310335721 cites W2751602375 @default.
- W4310335721 cites W2910394213 @default.
- W4310335721 cites W2939482086 @default.
- W4310335721 cites W2962247972 @default.
- W4310335721 cites W2975660480 @default.
- W4310335721 cites W3146983201 @default.
- W4310335721 doi "https://doi.org/10.22088/cjim.13.4.693" @default.
- W4310335721 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36420330" @default.
- W4310335721 hasPublicationYear "2022" @default.
- W4310335721 type Work @default.
- W4310335721 citedByCount "0" @default.
- W4310335721 crossrefType "journal-article" @default.
- W4310335721 hasAuthorship W4310335721A5015824657 @default.
- W4310335721 hasAuthorship W4310335721A5017632255 @default.
- W4310335721 hasAuthorship W4310335721A5020164418 @default.
- W4310335721 hasAuthorship W4310335721A5032872851 @default.
- W4310335721 hasAuthorship W4310335721A5037059208 @default.
- W4310335721 hasAuthorship W4310335721A5042651976 @default.
- W4310335721 hasAuthorship W4310335721A5060553992 @default.
- W4310335721 hasAuthorship W4310335721A5071197619 @default.
- W4310335721 hasAuthorship W4310335721A5082471003 @default.
- W4310335721 hasConcept C121608353 @default.
- W4310335721 hasConcept C126322002 @default.
- W4310335721 hasConcept C143998085 @default.
- W4310335721 hasConcept C170493617 @default.
- W4310335721 hasConcept C17991360 @default.
- W4310335721 hasConcept C203014093 @default.
- W4310335721 hasConcept C2107291 @default.
- W4310335721 hasConcept C526805850 @default.
- W4310335721 hasConcept C530470458 @default.
- W4310335721 hasConcept C71924100 @default.
- W4310335721 hasConcept C8891405 @default.
- W4310335721 hasConcept C90924648 @default.
- W4310335721 hasConceptScore W4310335721C121608353 @default.
- W4310335721 hasConceptScore W4310335721C126322002 @default.
- W4310335721 hasConceptScore W4310335721C143998085 @default.
- W4310335721 hasConceptScore W4310335721C170493617 @default.
- W4310335721 hasConceptScore W4310335721C17991360 @default.
- W4310335721 hasConceptScore W4310335721C203014093 @default.
- W4310335721 hasConceptScore W4310335721C2107291 @default.
- W4310335721 hasConceptScore W4310335721C526805850 @default.
- W4310335721 hasConceptScore W4310335721C530470458 @default.
- W4310335721 hasConceptScore W4310335721C71924100 @default.
- W4310335721 hasConceptScore W4310335721C8891405 @default.
- W4310335721 hasConceptScore W4310335721C90924648 @default.
- W4310335721 hasIssue "4" @default.
- W4310335721 hasLocation W43103357211 @default.
- W4310335721 hasLocation W43103357212 @default.
- W4310335721 hasOpenAccess W4310335721 @default.
- W4310335721 hasPrimaryLocation W43103357211 @default.
- W4310335721 hasRelatedWork W163255375 @default.
- W4310335721 hasRelatedWork W1983294736 @default.
- W4310335721 hasRelatedWork W2059257512 @default.
- W4310335721 hasRelatedWork W2154748714 @default.
- W4310335721 hasRelatedWork W2224319365 @default.
- W4310335721 hasRelatedWork W2392730113 @default.
- W4310335721 hasRelatedWork W2393644257 @default.
- W4310335721 hasRelatedWork W3004259476 @default.
- W4310335721 hasRelatedWork W3024560258 @default.
- W4310335721 hasRelatedWork W377899687 @default.
- W4310335721 hasVolume "13" @default.
- W4310335721 isParatext "false" @default.
- W4310335721 isRetracted "false" @default.
- W4310335721 workType "article" @default.