FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310360165> ?p ?o ?g. }

• W4310360165 abstract "Abstract Background Growing evidence suggests low and high maternal hemoglobin (Hb) concentrations may have adverse consequences for maternal and child health. There remain questions on specific Hb thresholds to define anemia and high Hb as well as how cutoffs may vary by anemia etiology and timing of assessment. Methods We conducted an updated systematic review (using PubMed and Cochrane Review) on the association between anemia (< 110 g/L) and high (≥ 130 g/L) maternal Hb concentrations at different stages of gestation (preconception; first, second, and third trimesters), as well as at any time point in pregnancy, and a range of maternal and infant health outcomes. We examined different cutoffs for defining anemia and high hemoglobin concentrations and performed stratified analyses by iron-deficiency anemia. We conducted a meta-analysis to obtain odds ratios, (OR), 95% confidence intervals. Results The updated systematic review included 148 studies. Anemia at any timepoint in pregnancy was associated with: low birthweight, LBW (OR (95% CI) 1.28 (1.22–1.35)), very low birthweight, VLBW (2.15 (1.47–3.13)), preterm birth, PTB (1.35 (1.29–1.42)), small-for-gestational age, SGA (1.11 (1.02–1.19)), stillbirth 1.43 (1.24–1.65)), perinatal mortality (1.75 (1.28–2.39)), neonatal mortality (1.25 (1.16–1.34), postpartum hemorrhage (1.69 (1.45–1.97)), transfusion (3.68 (2.58–5.26)), pre-eclampsia (1.57 (1.23–2.01)), and prenatal depression (1.44 (1.24–1.68)). For maternal mortality, the OR was higher when anemia was defined as Hb < 90 (4.83 (2.17–10.74)) compared with Hb < 100 (2.87 (1.08–7.67)). High maternal Hb was associated with: VLBW (1.35 (1.16–1.57)), PTB (1.12 (1.00-1.25)), SGA (1.17 (1.09–1.25)), stillbirth (1.32 (1.09–1.60)), maternal mortality (2.01 (1.12–3.61)), gestational diabetes (1.71 (1.19–2.46)), and pre-eclampsia (1.34 (1.16–1.56)). Stronger associations were noted earlier in pregnancy for anemia and adverse birth outcomes while the role of timing of high Hb was inconsistent. For anemia, lower cutoffs were associated with greater odds of poor outcomes; for high Hb, data were too limited to identify patterns. Information on anemia etiology was limited; relationships did not vary by iron-deficiency anemia. Conclusions Both anemia and high maternal Hb concentrations during pregnancy are strong predictors of adverse maternal and infant health outcomes. Additional research is need to establish healthy reference ranges and design effective interventions to optimize maternal Hb during pregnancy." @default.
• W4310360165 created "2022-12-09" @default.
• W4310360165 creator A5019302910 @default.
• W4310360165 creator A5032712086 @default.
• W4310360165 creator A5033010650 @default.
• W4310360165 creator A5036292128 @default.
• W4310360165 creator A5074609612 @default.
• W4310360165 creator A5076863420 @default.
• W4310360165 creator A5078813968 @default.
• W4310360165 date "2022-11-29" @default.
• W4310360165 modified "2023-09-25" @default.
• W4310360165 title "Maternal anemia and high hemoglobin concentrations and association with adverse maternal and infant health outcomes: an updated global systematic review and meta-analysis" @default.
• W4310360165 cites W1490174346 @default.
• W4310360165 cites W1502718480 @default.
• W4310360165 cites W1543998733 @default.
• W4310360165 cites W1883321301 @default.
• W4310360165 cites W1885276060 @default.
• W4310360165 cites W1919542579 @default.
• W4310360165 cites W1939663417 @default.
• W4310360165 cites W1961040664 @default.
• W4310360165 cites W1963301324 @default.
• W4310360165 cites W1966167112 @default.
• W4310360165 cites W1966522213 @default.
• W4310360165 cites W1971778304 @default.
• W4310360165 cites W1972413038 @default.
• W4310360165 cites W1981850514 @default.
• W4310360165 cites W1983564621 @default.
• W4310360165 cites W1983900190 @default.
• W4310360165 cites W1986838662 @default.
• W4310360165 cites W1991432771 @default.
• W4310360165 cites W1994348038 @default.
• W4310360165 cites W1994490503 @default.
• W4310360165 cites W2001321023 @default.
• W4310360165 cites W2002323967 @default.
• W4310360165 cites W2005817893 @default.
• W4310360165 cites W2006549122 @default.
• W4310360165 cites W2009859292 @default.
• W4310360165 cites W2013892115 @default.
• W4310360165 cites W2018556997 @default.
• W4310360165 cites W2018732090 @default.
• W4310360165 cites W2024072906 @default.
• W4310360165 cites W2024281712 @default.
• W4310360165 cites W2026127906 @default.
• W4310360165 cites W2026282457 @default.
• W4310360165 cites W2034917188 @default.
• W4310360165 cites W2035469956 @default.
• W4310360165 cites W2041405822 @default.
• W4310360165 cites W2048629003 @default.
• W4310360165 cites W2049249643 @default.
• W4310360165 cites W2049507774 @default.
• W4310360165 cites W2049978931 @default.
• W4310360165 cites W2050911637 @default.
• W4310360165 cites W2051911680 @default.
• W4310360165 cites W2069863807 @default.
• W4310360165 cites W2069868376 @default.
• W4310360165 cites W2071316791 @default.
• W4310360165 cites W2071678921 @default.
• W4310360165 cites W2073473798 @default.
• W4310360165 cites W2073592809 @default.
• W4310360165 cites W2078190754 @default.
• W4310360165 cites W2081627228 @default.
• W4310360165 cites W2086751840 @default.
• W4310360165 cites W2095229630 @default.
• W4310360165 cites W2096076604 @default.
• W4310360165 cites W2096734365 @default.
• W4310360165 cites W2098163166 @default.
• W4310360165 cites W2102523290 @default.
• W4310360165 cites W2110892642 @default.
• W4310360165 cites W2111335417 @default.
• W4310360165 cites W2115597344 @default.
• W4310360165 cites W2122036651 @default.
• W4310360165 cites W2124697431 @default.
• W4310360165 cites W2126473492 @default.
• W4310360165 cites W2127254446 @default.
• W4310360165 cites W2128219706 @default.
• W4310360165 cites W2128880003 @default.
• W4310360165 cites W2137602815 @default.
• W4310360165 cites W2143180186 @default.
• W4310360165 cites W2144955797 @default.
• W4310360165 cites W2150554910 @default.
• W4310360165 cites W2152102707 @default.
• W4310360165 cites W2152572261 @default.
• W4310360165 cites W2152672447 @default.
• W4310360165 cites W2152724914 @default.
• W4310360165 cites W2154209842 @default.
• W4310360165 cites W2154959709 @default.
• W4310360165 cites W2160833030 @default.
• W4310360165 cites W2162177010 @default.
• W4310360165 cites W2164385399 @default.
• W4310360165 cites W2167303938 @default.
• W4310360165 cites W2167657257 @default.
• W4310360165 cites W2171286823 @default.
• W4310360165 cites W2228344586 @default.
• W4310360165 cites W2284137610 @default.
• W4310360165 cites W2337979661 @default.
• W4310360165 cites W2346173973 @default.
• W4310360165 cites W2414726686 @default.
• W4310360165 cites W2461313594 @default.
• W4310360165 cites W2570128349 @default.
• W4310360165 cites W2594310849 @default.

• next