FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310363567> ?p ?o ?g. }

• W4310363567 endingPage "7050" @default.
• W4310363567 startingPage "7050" @default.
• W4310363567 abstract "Background: Quadruple therapy with polaprezinc provided an alternative to Helicobacter pylori eradication; however, the effect on gut microbiota remains uncertain. This study aims to identify whether polaprezinc-containing quadruple therapy causes adverse microbiota effects among asymptomatic adults, compared with bismuth therapy. Methods: This was a randomized control trial. One hundred asymptomatic H. pylori-infected adults were randomly (1:1) assigned to two treatment groups (polaprezinc-containing therapy, PQT; or bismuth-containing therapy, BQT). Fecal samples were collected from subjects before and 4–8 weeks after therapy. Samples were sequenced for the V4 regions of the 16S rRNA gene. Results: The relative abundance of the three dominant bacterial phyla (Bacteroidota, Firmicutes, and Proteobacteria) accounted for more than 95% of each treatment group. The alpha diversity between eradications that succeeded and those that failed had no significant difference (p > 0.05). After successful eradication, the alpha diversity in the BQT group decreased in comparison with the baseline (p < 0.05). Subjects who were successfully eradicated by BQT showed considerably lower alpha diversity indices than those of the PQT at follow-up (p < 0.05). The abundance of Parasutterella in subjects who were successfully eradicated by PQT was four times greater than that of BQT (q < 0.05). Conclusion: A 14-day PQT may be superior to BQT in maintaining short-term gut microbiota homeostasis after H. pylori treatment. Our findings preliminarily provide evidence of the short-term impacts of the gut microbiota after PQT treatment of H. pylori infection." @default.
• W4310363567 created "2022-12-09" @default.
• W4310363567 creator A5007467115 @default.
• W4310363567 creator A5017384752 @default.
• W4310363567 creator A5017489902 @default.
• W4310363567 creator A5024541563 @default.
• W4310363567 creator A5027835055 @default.
• W4310363567 creator A5031014951 @default.
• W4310363567 creator A5039907641 @default.
• W4310363567 creator A5047385805 @default.
• W4310363567 creator A5055047888 @default.
• W4310363567 creator A5056390389 @default.
• W4310363567 creator A5056467622 @default.
• W4310363567 creator A5069380386 @default.
• W4310363567 creator A5076073561 @default.
• W4310363567 creator A5078610967 @default.
• W4310363567 date "2022-11-29" @default.
• W4310363567 modified "2023-10-01" @default.
• W4310363567 title "The Effect of Quadruple Therapy with Polaprezinc or Bismuth on Gut Microbiota after Helicobacter pylori Eradication: A Randomized Controlled Trial" @default.
• W4310363567 cites W1938139711 @default.
• W4310363567 cites W1991008853 @default.
• W4310363567 cites W2000422965 @default.
• W4310363567 cites W2008181873 @default.
• W4310363567 cites W2019384249 @default.
• W4310363567 cites W2034285706 @default.
• W4310363567 cites W2061938579 @default.
• W4310363567 cites W2064401560 @default.
• W4310363567 cites W2081770941 @default.
• W4310363567 cites W2085470685 @default.
• W4310363567 cites W2114500058 @default.
• W4310363567 cites W2135443167 @default.
• W4310363567 cites W2140481064 @default.
• W4310363567 cites W2143269314 @default.
• W4310363567 cites W2160742577 @default.
• W4310363567 cites W2179868244 @default.
• W4310363567 cites W2224656683 @default.
• W4310363567 cites W2285446346 @default.
• W4310363567 cites W2289768434 @default.
• W4310363567 cites W2290767614 @default.
• W4310363567 cites W2401404581 @default.
• W4310363567 cites W2465212266 @default.
• W4310363567 cites W2527848138 @default.
• W4310363567 cites W2568895980 @default.
• W4310363567 cites W2593888231 @default.
• W4310363567 cites W2606327576 @default.
• W4310363567 cites W2609752905 @default.
• W4310363567 cites W2793923874 @default.
• W4310363567 cites W2794591685 @default.
• W4310363567 cites W2801096943 @default.
• W4310363567 cites W2802452842 @default.
• W4310363567 cites W2805732661 @default.
• W4310363567 cites W2805748601 @default.
• W4310363567 cites W2805922039 @default.
• W4310363567 cites W2807094730 @default.
• W4310363567 cites W2807721939 @default.
• W4310363567 cites W2809911284 @default.
• W4310363567 cites W2884186750 @default.
• W4310363567 cites W2907575274 @default.
• W4310363567 cites W2914883768 @default.
• W4310363567 cites W2916696793 @default.
• W4310363567 cites W2945047925 @default.
• W4310363567 cites W2945602721 @default.
• W4310363567 cites W2953923712 @default.
• W4310363567 cites W2963276645 @default.
• W4310363567 cites W2964931167 @default.
• W4310363567 cites W2974432944 @default.
• W4310363567 cites W2975291801 @default.
• W4310363567 cites W2979427590 @default.
• W4310363567 cites W2996468880 @default.
• W4310363567 cites W3003924738 @default.
• W4310363567 cites W30049446 @default.
• W4310363567 cites W3006910674 @default.
• W4310363567 cites W3010463498 @default.
• W4310363567 cites W3082483927 @default.
• W4310363567 cites W3104800468 @default.
• W4310363567 cites W3128646645 @default.
• W4310363567 cites W3196525798 @default.
• W4310363567 cites W4225852943 @default.
• W4310363567 cites W4241340425 @default.
• W4310363567 cites W4285090859 @default.
• W4310363567 cites W4291016468 @default.
• W4310363567 doi "https://doi.org/10.3390/jcm11237050" @default.
• W4310363567 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36498624" @default.
• W4310363567 hasPublicationYear "2022" @default.
• W4310363567 type Work @default.
• W4310363567 citedByCount "1" @default.
• W4310363567 countsByYear W43103635672023 @default.
• W4310363567 crossrefType "journal-article" @default.
• W4310363567 hasAuthorship W4310363567A5007467115 @default.
• W4310363567 hasAuthorship W4310363567A5017384752 @default.
• W4310363567 hasAuthorship W4310363567A5017489902 @default.
• W4310363567 hasAuthorship W4310363567A5024541563 @default.
• W4310363567 hasAuthorship W4310363567A5027835055 @default.
• W4310363567 hasAuthorship W4310363567A5031014951 @default.
• W4310363567 hasAuthorship W4310363567A5039907641 @default.
• W4310363567 hasAuthorship W4310363567A5047385805 @default.
• W4310363567 hasAuthorship W4310363567A5055047888 @default.
• W4310363567 hasAuthorship W4310363567A5056390389 @default.

• next