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• W4310366797 abstract "Artemisia afra Jacq. ex Willd. (Asteraceae), referred to as African wormwood, is an aromatic, perennial shrub that can grow up to 2 m in height. The finely divided leaves have a silver-green colour due to the presence of fine hairs. The plant is found in the mountainous regions of Africa, as far north as Ethiopia. In southern Africa, it occurs in Namibia, Zimbabwe, Swaziland (Eswatini), Lesotho and South Africa, where it is widespread and abundant. The plant is mainly used in the form of decoctions, infusions, poultices, or as an inhalant, to treat a range of ailments including coughs, colds, headaches, chills, colic, asthma, malaria, diabetes, influenza, convulsions, fever and rheumatism. In vitro and in vivo studies of the plant have indicated that it has promising antimicrobial, anti-oxidant, anti-inflammatory, antidiabetic and antimycobacterial activities. The essential oil composition has been reported to be highly variable, and several (artemisia ketone, 1,8-cineole, α-thujone, β-thujone, camphor and myrcenone) chemotypes have been described. Chemical profiles of A. afra essential oils, obtained by hydro-distillation were obtained using semi-automated high-performance thin-layer chromatography (HPTLC) and gas chromatography coupled to mass spectroscopy (GC–MS). The HPTLC plate, viewed under white light after derivatisation with anisaldehyde, confirms variation in the composition of the oils. The use of UPLC–MS for non-volatile qualitative analysis enabled the identification of scopolin, rutin, scopoletin, chrysoeriol, 3,5-di-O-caffeoylquinic acid and acacetin in the acetone:methanol extracts. The use of HPTLC indicated considerable variation in the phenolic compound composition of samples from different populations." @default.
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• W4310366797 date "2023-01-01" @default.
• W4310366797 modified "2023-09-28" @default.
• W4310366797 title "Artemisia afra" @default.
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• W4310366797 doi "https://doi.org/10.1016/b978-0-323-99794-2.00016-7" @default.
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