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• W4310366939 abstract "Leonotis leonurus (L.) R.Br. (Lamiaceae), commonly known as ‘wild dagga’, is a broadleaf evergreen plant indigenous to southern Africa. It is naturally distributed throughout the Eastern and Western Cape, KwaZulu-Natal and Mpumalanga provinces of South Africa, as well as certain parts of Zimbabwe and Mozambique. The plant is widely known for its medicinal and psychoactive properties. The leaves or flowers are administered in various forms such as decoctions or infusions. It is smoked for its mild euphoric effects, which are believed to be similar to that of cannabis, but with less potency. A decoction is used to relieve coughs, colds, bronchitis, and as a strong purgative and emmenagogue whilst infusions are used to treat chest infections, fever, headache, influenza and delayed menstruation. Gas chromatography coupled to mass spectrometry (GC–MS) analysis of the essential oils obtained by hydro-distillation revealed eight major constituents (trans-β-ocimene, cis-β-ocimene, β-caryophyllene, caryophyllene oxide, α-humulene, γ-elemene, α-cubebene and germacrene D), which represent about 50% of the total oil composition. Ultra-performance liquid chromatography coupled to mass spectrometry (UPLC–MS) and photodiode array detection profiles from dichloromethane:methanol (50:50 v/v) extracts revealed the presence of leoleorin A, leoleorin D, luteolin, 6-methoxyluteolin-4′-methyl ether and 9,13-epoxylabda-6(19),15(14)diol dilactone in samples collected from distinct populations. Using a semi-automated high-performance thin-layer chromatography (HPTLC) system, the chemical profiles of both the volatile oils and extracts were obtained. The marker compound, marrubiin, was identified in the chemical fingerprints of all the non-volatile samples on HPTLC plates viewed under white reflectance light, whilst the standard caryophyllene oxide appeared in all the volatile oils viewed under 366 nm radiation." @default.
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• W4310366939 date "2023-01-01" @default.
• W4310366939 modified "2023-09-26" @default.
• W4310366939 title "Leonotis leonurus" @default.
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• W4310366939 doi "https://doi.org/10.1016/b978-0-323-99794-2.00004-0" @default.
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