Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310373627> ?p ?o ?g. }
- W4310373627 endingPage "105454" @default.
- W4310373627 startingPage "105454" @default.
- W4310373627 abstract "It is well known that overnutrition, overweight, and obesity in children can modulate brain mechanisms of plasticity, monoaminergic systems, and mitochondrial function. The immediate effect of overnutrition during the developmental period has not been thoroughly examined in rats until the present. This study sought to evaluate the impact on adult rats of early life overfeeding and fluoxetine treatment from post-natal day 1 (PND1) to post-natal day 21 (PND21) relative to mitochondrial function, oxidative balance, and expression of specific monoaminergic genes in the hippocampus. The following were evaluated: mitochondrial function markers, oxidative stress biomarkers, dopamine-and serotonin-related genes, and BDNF mRNA levels. Overfeeding during the lactation period deregulates cellular metabolism and the monoaminergic systems in the hippocampus. Strikingly, serotonin modulation by fluoxetine treatment protected against some of the effects of early overnutrition. We conclude that overfeeding during brain development induce detrimental effects in mitochondria and in the genes that regulate homeostatic status that can be the molecular mechanisms related to neurological diseases." @default.
- W4310373627 created "2022-12-09" @default.
- W4310373627 creator A5016261853 @default.
- W4310373627 creator A5022234862 @default.
- W4310373627 creator A5043539014 @default.
- W4310373627 creator A5048137758 @default.
- W4310373627 creator A5070304027 @default.
- W4310373627 creator A5081003090 @default.
- W4310373627 creator A5082834316 @default.
- W4310373627 creator A5026124623 @default.
- W4310373627 date "2023-01-01" @default.
- W4310373627 modified "2023-09-26" @default.
- W4310373627 title "The immediate effect of overnutrition and fluoxetine treatment during the critical period of development on the hippocampus" @default.
- W4310373627 cites W1581414347 @default.
- W4310373627 cites W1583093482 @default.
- W4310373627 cites W1590457525 @default.
- W4310373627 cites W1693408209 @default.
- W4310373627 cites W1750690213 @default.
- W4310373627 cites W1803551358 @default.
- W4310373627 cites W183120241 @default.
- W4310373627 cites W191793640 @default.
- W4310373627 cites W1965814691 @default.
- W4310373627 cites W1965874599 @default.
- W4310373627 cites W1979268323 @default.
- W4310373627 cites W1982104904 @default.
- W4310373627 cites W1984316920 @default.
- W4310373627 cites W1999891390 @default.
- W4310373627 cites W2001657520 @default.
- W4310373627 cites W2006370393 @default.
- W4310373627 cites W2011718521 @default.
- W4310373627 cites W2013101568 @default.
- W4310373627 cites W2026261400 @default.
- W4310373627 cites W2048236085 @default.
- W4310373627 cites W2061196224 @default.
- W4310373627 cites W2063479489 @default.
- W4310373627 cites W2064769345 @default.
- W4310373627 cites W2070131849 @default.
- W4310373627 cites W2074367636 @default.
- W4310373627 cites W2078929761 @default.
- W4310373627 cites W2088762260 @default.
- W4310373627 cites W2107277218 @default.
- W4310373627 cites W2117131239 @default.
- W4310373627 cites W2137837355 @default.
- W4310373627 cites W2145672755 @default.
- W4310373627 cites W2146102375 @default.
- W4310373627 cites W2549902875 @default.
- W4310373627 cites W2557377799 @default.
- W4310373627 cites W2567752608 @default.
- W4310373627 cites W2887672658 @default.
- W4310373627 cites W2904594793 @default.
- W4310373627 cites W2905573083 @default.
- W4310373627 cites W2910650156 @default.
- W4310373627 cites W2947408808 @default.
- W4310373627 cites W2954262572 @default.
- W4310373627 cites W2995945170 @default.
- W4310373627 cites W3012145538 @default.
- W4310373627 cites W3019080577 @default.
- W4310373627 cites W3024768985 @default.
- W4310373627 cites W3025724079 @default.
- W4310373627 cites W3027298771 @default.
- W4310373627 cites W3040258846 @default.
- W4310373627 cites W3041001204 @default.
- W4310373627 cites W3048409224 @default.
- W4310373627 cites W3080423507 @default.
- W4310373627 cites W3081197732 @default.
- W4310373627 cites W3086124097 @default.
- W4310373627 cites W3110854640 @default.
- W4310373627 cites W3119525582 @default.
- W4310373627 cites W3161265576 @default.
- W4310373627 cites W3177270611 @default.
- W4310373627 cites W3199588575 @default.
- W4310373627 cites W3201995770 @default.
- W4310373627 cites W4225287891 @default.
- W4310373627 cites W4293247451 @default.
- W4310373627 cites W4294216491 @default.
- W4310373627 doi "https://doi.org/10.1016/j.neuint.2022.105454" @default.
- W4310373627 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36462683" @default.
- W4310373627 hasPublicationYear "2023" @default.
- W4310373627 type Work @default.
- W4310373627 citedByCount "1" @default.
- W4310373627 countsByYear W43103736272023 @default.
- W4310373627 crossrefType "journal-article" @default.
- W4310373627 hasAuthorship W4310373627A5016261853 @default.
- W4310373627 hasAuthorship W4310373627A5022234862 @default.
- W4310373627 hasAuthorship W4310373627A5026124623 @default.
- W4310373627 hasAuthorship W4310373627A5043539014 @default.
- W4310373627 hasAuthorship W4310373627A5048137758 @default.
- W4310373627 hasAuthorship W4310373627A5070304027 @default.
- W4310373627 hasAuthorship W4310373627A5081003090 @default.
- W4310373627 hasAuthorship W4310373627A5082834316 @default.
- W4310373627 hasConcept C121332964 @default.
- W4310373627 hasConcept C126322002 @default.
- W4310373627 hasConcept C134018914 @default.
- W4310373627 hasConcept C170493617 @default.
- W4310373627 hasConcept C24890656 @default.
- W4310373627 hasConcept C2775864247 @default.
- W4310373627 hasConcept C2777229759 @default.
- W4310373627 hasConcept C2778302649 @default.