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- W4310377526 abstract "The combination of sacubitril and valsartan has recently become eligible for reimbursement in Japan for the treatment of hypertension. However, the real-world clinical efficacy of sacubitril/valsartan in patients with hypertension who are taking multiple anti-hypertensive medications remains to be characterized. We treated a man in his late 40s who had undergone a percutaneous coronary intervention and had hypertension that was refractory to multiple anti-hypertensive medications. We initiated sacubitril/valsartan 200 mg/day as an add-on therapy, and 3 months later, his blood pressure had decreased from 154/78 mmHg to 134/70 mmHg, in the absence of any drug-related adverse events. Furthermore, his left ventricular mass index had improved from 135 g/m2 to 112 g/m2. Thus, sacubitril/valsartan might ameliorate hypertrophy in patients with hypertension." @default.
- W4310377526 created "2022-12-10" @default.
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- W4310377526 date "2022-11-01" @default.
- W4310377526 modified "2023-09-25" @default.
- W4310377526 title "Effect of add-on sacubitril/valsartan on the left ventricular hypertrophy of a patient with hypertension" @default.
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- W4310377526 doi "https://doi.org/10.1177/03000605221138480" @default.
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