Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310379612> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W4310379612 endingPage "42" @default.
- W4310379612 startingPage "35" @default.
- W4310379612 abstract "Systemic lupus erythematosus (SLE) is an autoimmune disease, with hydroxychloroquine being the main therapeutic agent for the treatment of SLE. This research explored the effects of hydroxychloroquine combined with low-dose aspirin on maternal and infant outcomes and cytokines of pregnant women with SLE.Ninety pregnant women with SLE were divided into the hydroxychloroquine (HCQ) group (45 cases) and the hydroxychloroquine combined with low-dose aspirin (HCQASP) group (45 cases) by random number table. Patients in the HCQ group were treated with oral administration of hydroxychloroquine, while patients in the HCQASP group were treated with low-dose aspirin based on oral administration of hydroxychloroquine. Pregnancy outcomes, fetal outcomes, and cytokine levels were statistically analyzed.The HCQASP group had a significantly higher proportion of full-term pregnancies and a significantly lower proportion of hypertension, prematurity, and pregnancy loss than the HCQ group. Neonates in the HCQASP group also had significantly higher birth weights and Apgar scores and a significantly lower proportion of neonatal asphyxia than the HCQ group. After treatment, the HCQASP group had significantly higher interleukin (IL-2) and interferon (IFN)-γ levels and significantly lower IL-4 and IL-10 levels than the HCQ group.Hydroxychloroquine combined with low-dose aspirin can effectively improve the pregnancy outcomes of pregnant women with SLE by affecting the levels of T helper (Th) 2 and Th1 cytokines." @default.
- W4310379612 created "2022-12-10" @default.
- W4310379612 creator A5009327702 @default.
- W4310379612 creator A5038305059 @default.
- W4310379612 creator A5042467158 @default.
- W4310379612 creator A5057135582 @default.
- W4310379612 date "2022-11-30" @default.
- W4310379612 modified "2023-10-18" @default.
- W4310379612 title "Benefits of Hydroxychloroquine Combined with Low-Dose Aspirin on Pregnancy Outcomes and Serum Cytokines in Pregnant Women with Systemic Lupus Erythematosus" @default.
- W4310379612 cites W1964821535 @default.
- W4310379612 cites W1985460551 @default.
- W4310379612 cites W1988763292 @default.
- W4310379612 cites W2022208874 @default.
- W4310379612 cites W2029293405 @default.
- W4310379612 cites W2035576877 @default.
- W4310379612 cites W2039236157 @default.
- W4310379612 cites W2056493149 @default.
- W4310379612 cites W2078918202 @default.
- W4310379612 cites W2344687002 @default.
- W4310379612 cites W2560774983 @default.
- W4310379612 cites W2580568848 @default.
- W4310379612 cites W2792738967 @default.
- W4310379612 cites W2805286704 @default.
- W4310379612 cites W2892484807 @default.
- W4310379612 cites W2904302991 @default.
- W4310379612 cites W2972505837 @default.
- W4310379612 cites W2990740152 @default.
- W4310379612 cites W3007452564 @default.
- W4310379612 cites W3007675505 @default.
- W4310379612 cites W3022548816 @default.
- W4310379612 cites W3026505801 @default.
- W4310379612 cites W3038129072 @default.
- W4310379612 cites W3108385267 @default.
- W4310379612 cites W3183642905 @default.
- W4310379612 cites W3193278565 @default.
- W4310379612 cites W4231495302 @default.
- W4310379612 cites W4282840336 @default.
- W4310379612 cites W4293111800 @default.
- W4310379612 doi "https://doi.org/10.1007/s40268-022-00408-0" @default.
- W4310379612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36449182" @default.
- W4310379612 hasPublicationYear "2022" @default.
- W4310379612 type Work @default.
- W4310379612 citedByCount "0" @default.
- W4310379612 crossrefType "journal-article" @default.
- W4310379612 hasAuthorship W4310379612A5009327702 @default.
- W4310379612 hasAuthorship W4310379612A5038305059 @default.
- W4310379612 hasAuthorship W4310379612A5042467158 @default.
- W4310379612 hasAuthorship W4310379612A5057135582 @default.
- W4310379612 hasBestOaLocation W43103796121 @default.
- W4310379612 hasConcept C126322002 @default.
- W4310379612 hasConcept C131872663 @default.
- W4310379612 hasConcept C203014093 @default.
- W4310379612 hasConcept C2777628954 @default.
- W4310379612 hasConcept C2779123688 @default.
- W4310379612 hasConcept C2779134260 @default.
- W4310379612 hasConcept C2779234561 @default.
- W4310379612 hasConcept C3008058167 @default.
- W4310379612 hasConcept C524204448 @default.
- W4310379612 hasConcept C54355233 @default.
- W4310379612 hasConcept C71924100 @default.
- W4310379612 hasConcept C86803240 @default.
- W4310379612 hasConcept C90924648 @default.
- W4310379612 hasConceptScore W4310379612C126322002 @default.
- W4310379612 hasConceptScore W4310379612C131872663 @default.
- W4310379612 hasConceptScore W4310379612C203014093 @default.
- W4310379612 hasConceptScore W4310379612C2777628954 @default.
- W4310379612 hasConceptScore W4310379612C2779123688 @default.
- W4310379612 hasConceptScore W4310379612C2779134260 @default.
- W4310379612 hasConceptScore W4310379612C2779234561 @default.
- W4310379612 hasConceptScore W4310379612C3008058167 @default.
- W4310379612 hasConceptScore W4310379612C524204448 @default.
- W4310379612 hasConceptScore W4310379612C54355233 @default.
- W4310379612 hasConceptScore W4310379612C71924100 @default.
- W4310379612 hasConceptScore W4310379612C86803240 @default.
- W4310379612 hasConceptScore W4310379612C90924648 @default.
- W4310379612 hasIssue "1" @default.
- W4310379612 hasLocation W43103796121 @default.
- W4310379612 hasLocation W43103796122 @default.
- W4310379612 hasLocation W43103796123 @default.
- W4310379612 hasOpenAccess W4310379612 @default.
- W4310379612 hasPrimaryLocation W43103796121 @default.
- W4310379612 hasRelatedWork W2019059391 @default.
- W4310379612 hasRelatedWork W2064286441 @default.
- W4310379612 hasRelatedWork W2332797319 @default.
- W4310379612 hasRelatedWork W2367823310 @default.
- W4310379612 hasRelatedWork W2542248393 @default.
- W4310379612 hasRelatedWork W2601158643 @default.
- W4310379612 hasRelatedWork W2907723261 @default.
- W4310379612 hasRelatedWork W2950169628 @default.
- W4310379612 hasRelatedWork W2978156863 @default.
- W4310379612 hasRelatedWork W4249342726 @default.
- W4310379612 hasVolume "23" @default.
- W4310379612 isParatext "false" @default.
- W4310379612 isRetracted "false" @default.
- W4310379612 workType "article" @default.