FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310490804> ?p ?o ?g. }

• W4310490804 abstract "Introduction Brain metabolism deteriorates during brain death, suggesting that cerebral metabolic measurements could serve as a prognostic factor. The application of transcranial Doppler can be useful in evaluating patients evolving to brain death. Resting energy expenditure is lower than expected in patients with brain death, and this is caused by the decrease in cerebral blood flow and consequently lower oxygen supply. The primary aim of this retrospective study is to investigate the early metabolic changes in patients with clinical criteria of brain death and examine if these changes are related to a gradual decrease in blood flow velocities in the middle cerebral artery. Methods All consecutive patients from 1st June 2018 to 30th April 2022, admitted to the ICU with brain injury and a GCS ≤ 8, were included retrospectively in the study. Patients were allocated into two groups: Group A, patients without clinical signs of brain death (n = 32), and Group B, patients with brain death (n = 34). In each group, three sets of metabolic measurements were performed concomitantly with cerebral blood flow velocities using transcranial Doppler (a) upon admission to the ICU, (b) once hemodynamic stabilization was obtained, and (c) 48 hours after their hemodynamic stabilization or when brain death was confirmed by clinical criteria. Resting energy expenditure (REE) measurements were performed using a metabolic computer. Cerebral blood flow velocities were measured after a period of 30 min using a 2-MHZ 2D ultrasound probe. Results Brain-dead patients had a significant decrease in their metabolic parameters as the cerebral blood flow velocities recorded with the transcranial Doppler deteriorated, (REE Group A = 1667.65 ± 597 vs Group B = 1376.12 ± 615, p = 0.05 and REE predicted Group A = 113.19 ± 44.9 vs Group B = 93.29 ± 41.5, p = 0.066 for measurement 1; REE Group A = 1844 ± 530.9 vs Group B = 1219.97 ± 489, p < 0.001 and REE predicted Group A = 124.38 ± 39 vs Group B = 81.35 ± 30.4, p < 0.001 for measurement 2; REE Group A = 1750.97 ± 414, p < 0.001 and REE predicted Group A = 116.38 ± 19.2 vs Group B = 56.09 ± 19.6, p < 0.001 for measurement 3). Multiple stepwise regression analysis revealed a strong relationship between age, the worsening of the blood flow velocities pattern, and the decrease in REE (multiple R = 0.264, F = 5.55, p = 0.009). Furthermore, a statistically significant correlation was found between temperature and REE (correlation coefficient = 0.500, 0.674, 0.784 for measurements 1, 2, and 3, respectively, and p < 0.001 for all measures). Conclusions In brain-dead patients, the gradual decrease in cerebral blood flow leads to a decrease in REE as well as thermogenetic control. These changes can be detected early after the patient's admission to the ICU." @default.
• W4310490804 created "2022-12-11" @default.
• W4310490804 creator A5015078535 @default.
• W4310490804 creator A5025201893 @default.
• W4310490804 creator A5041896134 @default.
• W4310490804 creator A5055023854 @default.
• W4310490804 creator A5068016724 @default.
• W4310490804 date "2022-12-01" @default.
• W4310490804 modified "2023-10-01" @default.
• W4310490804 title "Relationships Between Resting Energy Expenditure and Transcranial Doppler Measurements in Patients With and Without Brain Death" @default.
• W4310490804 cites W191507371 @default.
• W4310490804 cites W1928562131 @default.
• W4310490804 cites W1973387083 @default.
• W4310490804 cites W1978749502 @default.
• W4310490804 cites W2018296721 @default.
• W4310490804 cites W2041811148 @default.
• W4310490804 cites W2042616631 @default.
• W4310490804 cites W2048126798 @default.
• W4310490804 cites W2052721374 @default.
• W4310490804 cites W2069104450 @default.
• W4310490804 cites W2075432924 @default.
• W4310490804 cites W2089833342 @default.
• W4310490804 cites W2103533085 @default.
• W4310490804 cites W2120936183 @default.
• W4310490804 cites W2122356800 @default.
• W4310490804 cites W2129403811 @default.
• W4310490804 cites W2141233392 @default.
• W4310490804 cites W2252947695 @default.
• W4310490804 cites W2412206432 @default.
• W4310490804 cites W2412392785 @default.
• W4310490804 cites W2574587499 @default.
• W4310490804 cites W2944190574 @default.
• W4310490804 cites W2954629263 @default.
• W4310490804 cites W2982053296 @default.
• W4310490804 cites W3030613995 @default.
• W4310490804 cites W3047035166 @default.
• W4310490804 cites W3157183531 @default.
• W4310490804 cites W35810311 @default.
• W4310490804 cites W4206285222 @default.
• W4310490804 cites W4244950386 @default.
• W4310490804 cites W4297040316 @default.
• W4310490804 doi "https://doi.org/10.7759/cureus.32093" @default.
• W4310490804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36601217" @default.
• W4310490804 hasPublicationYear "2022" @default.
• W4310490804 type Work @default.
• W4310490804 citedByCount "0" @default.
• W4310490804 crossrefType "journal-article" @default.
• W4310490804 hasAuthorship W4310490804A5015078535 @default.
• W4310490804 hasAuthorship W4310490804A5025201893 @default.
• W4310490804 hasAuthorship W4310490804A5041896134 @default.
• W4310490804 hasAuthorship W4310490804A5055023854 @default.
• W4310490804 hasAuthorship W4310490804A5068016724 @default.
• W4310490804 hasBestOaLocation W43104908041 @default.
• W4310490804 hasConcept C126322002 @default.
• W4310490804 hasConcept C157767197 @default.
• W4310490804 hasConcept C158846371 @default.
• W4310490804 hasConcept C164705383 @default.
• W4310490804 hasConcept C178853913 @default.
• W4310490804 hasConcept C191616109 @default.
• W4310490804 hasConcept C2775841333 @default.
• W4310490804 hasConcept C42219234 @default.
• W4310490804 hasConcept C541997718 @default.
• W4310490804 hasConcept C71924100 @default.
• W4310490804 hasConceptScore W4310490804C126322002 @default.
• W4310490804 hasConceptScore W4310490804C157767197 @default.
• W4310490804 hasConceptScore W4310490804C158846371 @default.
• W4310490804 hasConceptScore W4310490804C164705383 @default.
• W4310490804 hasConceptScore W4310490804C178853913 @default.
• W4310490804 hasConceptScore W4310490804C191616109 @default.
• W4310490804 hasConceptScore W4310490804C2775841333 @default.
• W4310490804 hasConceptScore W4310490804C42219234 @default.
• W4310490804 hasConceptScore W4310490804C541997718 @default.
• W4310490804 hasConceptScore W4310490804C71924100 @default.
• W4310490804 hasLocation W43104908041 @default.
• W4310490804 hasLocation W43104908042 @default.
• W4310490804 hasLocation W43104908043 @default.
• W4310490804 hasOpenAccess W4310490804 @default.
• W4310490804 hasPrimaryLocation W43104908041 @default.
• W4310490804 hasRelatedWork W1975138221 @default.
• W4310490804 hasRelatedWork W2027906016 @default.
• W4310490804 hasRelatedWork W2111607494 @default.
• W4310490804 hasRelatedWork W2147670770 @default.
• W4310490804 hasRelatedWork W2348288439 @default.
• W4310490804 hasRelatedWork W2359058955 @default.
• W4310490804 hasRelatedWork W2366927742 @default.
• W4310490804 hasRelatedWork W2955794190 @default.
• W4310490804 hasRelatedWork W3142095525 @default.
• W4310490804 hasRelatedWork W4245495675 @default.
• W4310490804 isParatext "false" @default.
• W4310490804 isRetracted "false" @default.
• W4310490804 workType "article" @default.