FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310495775> ?p ?o ?g. }

• W4310495775 abstract "Abstract The Illumina EPIC array is widely used for high-throughput profiling of DNA cytosine modifications in human samples, covering more than 850,000 modification sites across various genomic features. The application of this platform is expected to provide novel insights into the epigenetic contribution to human complex traits and diseases. Considering the diverse inter-population genetic and epigenetic variation, it will benefit the research community with a comprehensive characterization of this platform for its applicability to major global populations. Specifically, we mapped 866,836 CpG probes from the EPIC array to the human genome reference. We detected 91,034 CpG probes that did not align reliably to the human genome reference. In addition, 21,256 CpG probes were found to ambiguously map to multiple loci in the human genome, and 448 probes showing inaccurate genomic information from the original Illumina annotations. We further characterized those uniquely mapped CpG probes in terms of whether they contained common genetic variants, i.e., single nucleotide polymorphisms (SNPs), in major global populations, by utilizing the 1000 Genomes Project data. A list of optimal CpG probes on the EPIC array was generated for major global populations, with the aim of providing a resource to facilitate future studies of diverse human populations. In conclusion, our analysis indicated that studies of diverse human populations using the EPIC array would be benefited by taking into account of the technical features of this platform." @default.
• W4310495775 created "2022-12-11" @default.
• W4310495775 creator A5049407947 @default.
• W4310495775 creator A5066515490 @default.
• W4310495775 creator A5076699095 @default.
• W4310495775 date "2022-12-01" @default.
• W4310495775 modified "2023-09-25" @default.
• W4310495775 title "Characterization of the Illumina EPIC array for optimal applications in epigenetic research targeting diverse human populations" @default.
• W4310495775 cites W1912672559 @default.
• W4310495775 cites W1975528145 @default.
• W4310495775 cites W2004172747 @default.
• W4310495775 cites W2026682494 @default.
• W4310495775 cites W2029654103 @default.
• W4310495775 cites W2050105063 @default.
• W4310495775 cites W2081502106 @default.
• W4310495775 cites W2096791516 @default.
• W4310495775 cites W2104549677 @default.
• W4310495775 cites W2113263282 @default.
• W4310495775 cites W2134237614 @default.
• W4310495775 cites W2136145671 @default.
• W4310495775 cites W2141105144 @default.
• W4310495775 cites W2171777347 @default.
• W4310495775 cites W2281754639 @default.
• W4310495775 cites W2343475249 @default.
• W4310495775 cites W2346059151 @default.
• W4310495775 cites W2469748284 @default.
• W4310495775 cites W2529024004 @default.
• W4310495775 cites W2537310520 @default.
• W4310495775 cites W2560163852 @default.
• W4310495775 cites W3113573191 @default.
• W4310495775 doi "https://doi.org/10.1186/s43682-022-00015-9" @default.
• W4310495775 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36466778" @default.
• W4310495775 hasPublicationYear "2022" @default.
• W4310495775 type Work @default.
• W4310495775 citedByCount "0" @default.
• W4310495775 crossrefType "journal-article" @default.
• W4310495775 hasAuthorship W4310495775A5049407947 @default.
• W4310495775 hasAuthorship W4310495775A5066515490 @default.
• W4310495775 hasAuthorship W4310495775A5076699095 @default.
• W4310495775 hasBestOaLocation W43104957751 @default.
• W4310495775 hasConcept C104317684 @default.
• W4310495775 hasConcept C115519274 @default.
• W4310495775 hasConcept C124952713 @default.
• W4310495775 hasConcept C135763542 @default.
• W4310495775 hasConcept C140173407 @default.
• W4310495775 hasConcept C141231307 @default.
• W4310495775 hasConcept C142362112 @default.
• W4310495775 hasConcept C144024400 @default.
• W4310495775 hasConcept C149923435 @default.
• W4310495775 hasConcept C150194340 @default.
• W4310495775 hasConcept C153209595 @default.
• W4310495775 hasConcept C189206191 @default.
• W4310495775 hasConcept C190727270 @default.
• W4310495775 hasConcept C192953774 @default.
• W4310495775 hasConcept C197077220 @default.
• W4310495775 hasConcept C2908647359 @default.
• W4310495775 hasConcept C40583040 @default.
• W4310495775 hasConcept C41091548 @default.
• W4310495775 hasConcept C54355233 @default.
• W4310495775 hasConcept C70721500 @default.
• W4310495775 hasConcept C78458016 @default.
• W4310495775 hasConcept C86803240 @default.
• W4310495775 hasConceptScore W4310495775C104317684 @default.
• W4310495775 hasConceptScore W4310495775C115519274 @default.
• W4310495775 hasConceptScore W4310495775C124952713 @default.
• W4310495775 hasConceptScore W4310495775C135763542 @default.
• W4310495775 hasConceptScore W4310495775C140173407 @default.
• W4310495775 hasConceptScore W4310495775C141231307 @default.
• W4310495775 hasConceptScore W4310495775C142362112 @default.
• W4310495775 hasConceptScore W4310495775C144024400 @default.
• W4310495775 hasConceptScore W4310495775C149923435 @default.
• W4310495775 hasConceptScore W4310495775C150194340 @default.
• W4310495775 hasConceptScore W4310495775C153209595 @default.
• W4310495775 hasConceptScore W4310495775C189206191 @default.
• W4310495775 hasConceptScore W4310495775C190727270 @default.
• W4310495775 hasConceptScore W4310495775C192953774 @default.
• W4310495775 hasConceptScore W4310495775C197077220 @default.
• W4310495775 hasConceptScore W4310495775C2908647359 @default.
• W4310495775 hasConceptScore W4310495775C40583040 @default.
• W4310495775 hasConceptScore W4310495775C41091548 @default.
• W4310495775 hasConceptScore W4310495775C54355233 @default.
• W4310495775 hasConceptScore W4310495775C70721500 @default.
• W4310495775 hasConceptScore W4310495775C78458016 @default.
• W4310495775 hasConceptScore W4310495775C86803240 @default.
• W4310495775 hasFunder F4320332161 @default.
• W4310495775 hasIssue "1" @default.
• W4310495775 hasLocation W43104957751 @default.
• W4310495775 hasLocation W43104957752 @default.
• W4310495775 hasLocation W43104957753 @default.
• W4310495775 hasLocation W43104957754 @default.
• W4310495775 hasOpenAccess W4310495775 @default.
• W4310495775 hasPrimaryLocation W43104957751 @default.
• W4310495775 hasRelatedWork W1970464961 @default.
• W4310495775 hasRelatedWork W1973778874 @default.
• W4310495775 hasRelatedWork W2038826578 @default.
• W4310495775 hasRelatedWork W2136970997 @default.
• W4310495775 hasRelatedWork W2476776109 @default.
• W4310495775 hasRelatedWork W3005920804 @default.
• W4310495775 hasRelatedWork W3198690628 @default.
• W4310495775 hasRelatedWork W4310701073 @default.

• next