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- W4310506280 abstract "<p> </p> <p><strong>BACKGROUND: </strong>Optimal length of biliopancreatic (BP) and Roux limb in Roux-en-Y gastric bypass (RYGB) for improved glycemic control are not known.</p> <p><strong>PURPOSE: </strong>To investigate how the lengths of the BP and Roux limbs in RYGB differentially affect postoperative glycemic outcomes in patients with type 2 diabetes.</p> <p><strong>DATA SOURCES: </strong>Systematic literature search using the PubMed, EMBASE, and the Cochrane Library databases.</p> <p><strong>STUDY SELECTION: </strong>Studies that reported glycemic outcomes after RYGB and lengths of the BP and Roux limbs.</p> <p><strong>DATA EXTRACTION: </strong>Twenty-eight articles were included for data extraction. Glycemic outcomes after RYGB were assessed using two definitions: remission and improvement.</p> <p><strong>DATA SYNTHESIS: </strong> We categorized the included studies into four groups according to the BP and Roux limb lengths. The type 2 diabetes remission/improvement rates (95% confidence interval [CI]) were as follows: long BP‒long Roux group, 0.80 (0.70‒0.90)/0.81 (0.73‒0.89); long BP‒short Roux group, 0.76 (0.66‒0.87)/0.82 (0.75–0.89); short BP‒long Roux group 0.57 (0.36‒0.78)/0.64 (0.53‒0.75); short BP‒short Roux group, 0.62 (0.43‒0.80)/0.53 (0.45‒0.61). Meta-regression analysis also showed that a longer BP limb resulted in higher postoperative type 2 diabetes remission and improvement rates, whereas a longer Roux limb did not. There was no significant difference or heterogeneity in baseline characteristics, including diabetes-related variables, among the four groups.</p> <p><strong>LIMITATIONS: </strong>Not all included studies were randomized controlled trials.</p> <p><strong>CONCLUSIONS: </strong>Longer BP limb length led to higher rates of type 2 diabetes remission and improvement by 1 year after RYGB than the longer Roux limb length.</p> <p> </p>" @default.
- W4310506280 created "2022-12-11" @default.
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- W4310506280 date "2022-12-01" @default.
- W4310506280 modified "2023-10-16" @default.
- W4310506280 title "Biliopancreatic Limb Length as a Potential Key Factor in Superior Glycemic Outcomes After Roux-en-Y Gastric Bypass in Patients with Type 2 Diabetes: A Meta-analysis" @default.
- W4310506280 doi "https://doi.org/10.2337/figshare.20809063.v1" @default.
- W4310506280 hasPublicationYear "2022" @default.
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