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- W4310540152 abstract "<div>Continuous efforts in the development of monoamine oxidase inhibitors</div><div>prompted the search for effective strategies for the design of novel drugs candidate.</div><div>Thankfully, nature often provides scaffolds useful for the promotion of novel</div><div>exploitable chemical entities. In this regard, aurones (a class of uncommon flavonoids)</div><div>and their structural related analogues may play an important role in the development of</div><div>monoamine oxidase inhibitors. The target prediction of the simplest aurone (2-</div><div>benzylidenebenzofuran-3(2H)-one) clearly suggests that this compound probably</div><div>affects MAO (monoamine oxidase) enzymes, which is in accordance with the recently</div><div>reported literature. The current chapter reports the recent discoveries involving aurones</div><div>and their structurally related analogues as MAO inhibitors, describing detailed</div><div>structure-activity relationships (SARs) for each subgroup of compounds.</div>" @default.
- W4310540152 created "2022-12-11" @default.
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- W4310540152 date "2022-12-01" @default.
- W4310540152 modified "2023-09-28" @default.
- W4310540152 title "Aurone Scaffold and Structural Analogues for the Development of Monoamine Oxidase (MAO) Inhibitors" @default.
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- W4310540152 doi "https://doi.org/10.2174/9789815079098122010012" @default.
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