Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310567037> ?p ?o ?g. }
- W4310567037 abstract "This review highlights the role of several immunomodulating elements contributing to the tumor microenvironment of various pediatric renal tumors including Wilms tumor. The roles of innate and adaptive immune cells in renal tumors are summarized as well as immunomodulatory cytokines and other proteins. The expression and the predictive role of checkpoint modulators like PD-L1 and immunomodulating proteins like glypican-3, B7-H3, COX-2 are highlighted with a translational view toward potential therapeutic innovations. We further discuss the current state of preclinical models in advancing this field of study. Finally, examples of clinical trials of immunomodulating strategies such as monoclonal antibodies and chimeric antigen receptor T (CAR-T) cells for relapsed/refractory/progressive pediatric renal tumors are described." @default.
- W4310567037 created "2022-12-12" @default.
- W4310567037 creator A5002067954 @default.
- W4310567037 creator A5002986008 @default.
- W4310567037 creator A5040392709 @default.
- W4310567037 creator A5041372516 @default.
- W4310567037 creator A5055053315 @default.
- W4310567037 creator A5070914960 @default.
- W4310567037 creator A5085372074 @default.
- W4310567037 creator A5087072662 @default.
- W4310567037 date "2022-11-30" @default.
- W4310567037 modified "2023-09-30" @default.
- W4310567037 title "The tumor microenvironment and immune targeting therapy in pediatric renal tumors" @default.
- W4310567037 cites W1802574002 @default.
- W4310567037 cites W1965157206 @default.
- W4310567037 cites W1978407285 @default.
- W4310567037 cites W1986679591 @default.
- W4310567037 cites W1987430342 @default.
- W4310567037 cites W1996036807 @default.
- W4310567037 cites W1996433050 @default.
- W4310567037 cites W1997883792 @default.
- W4310567037 cites W1998466036 @default.
- W4310567037 cites W2000582076 @default.
- W4310567037 cites W2002513358 @default.
- W4310567037 cites W2008534009 @default.
- W4310567037 cites W2010916968 @default.
- W4310567037 cites W2026715510 @default.
- W4310567037 cites W2037213236 @default.
- W4310567037 cites W2050623189 @default.
- W4310567037 cites W2052644931 @default.
- W4310567037 cites W2072419473 @default.
- W4310567037 cites W2073116534 @default.
- W4310567037 cites W2084210219 @default.
- W4310567037 cites W2085713699 @default.
- W4310567037 cites W2091943025 @default.
- W4310567037 cites W2092951725 @default.
- W4310567037 cites W2094273481 @default.
- W4310567037 cites W2096322385 @default.
- W4310567037 cites W2107752337 @default.
- W4310567037 cites W2110172571 @default.
- W4310567037 cites W2110844151 @default.
- W4310567037 cites W2114691869 @default.
- W4310567037 cites W2117180730 @default.
- W4310567037 cites W2126418396 @default.
- W4310567037 cites W2127209729 @default.
- W4310567037 cites W2133233410 @default.
- W4310567037 cites W2135045156 @default.
- W4310567037 cites W2142153200 @default.
- W4310567037 cites W2152714839 @default.
- W4310567037 cites W2157030129 @default.
- W4310567037 cites W2333454910 @default.
- W4310567037 cites W2465922150 @default.
- W4310567037 cites W2592215614 @default.
- W4310567037 cites W2613697898 @default.
- W4310567037 cites W2615473878 @default.
- W4310567037 cites W2619595919 @default.
- W4310567037 cites W2747947852 @default.
- W4310567037 cites W2754171246 @default.
- W4310567037 cites W2765282913 @default.
- W4310567037 cites W2771057425 @default.
- W4310567037 cites W2773981699 @default.
- W4310567037 cites W2788735115 @default.
- W4310567037 cites W2789869568 @default.
- W4310567037 cites W2808497725 @default.
- W4310567037 cites W2808615542 @default.
- W4310567037 cites W2809278685 @default.
- W4310567037 cites W2832813378 @default.
- W4310567037 cites W2838710545 @default.
- W4310567037 cites W2887326710 @default.
- W4310567037 cites W2889081079 @default.
- W4310567037 cites W2916357429 @default.
- W4310567037 cites W2923957458 @default.
- W4310567037 cites W2958203556 @default.
- W4310567037 cites W2964620721 @default.
- W4310567037 cites W2967658120 @default.
- W4310567037 cites W2976248430 @default.
- W4310567037 cites W2978117166 @default.
- W4310567037 cites W2980113327 @default.
- W4310567037 cites W2985059970 @default.
- W4310567037 cites W2986345436 @default.
- W4310567037 cites W2986901366 @default.
- W4310567037 cites W2991701263 @default.
- W4310567037 cites W2991941178 @default.
- W4310567037 cites W3000387638 @default.
- W4310567037 cites W3013075350 @default.
- W4310567037 cites W3015372699 @default.
- W4310567037 cites W3037407687 @default.
- W4310567037 cites W3110816622 @default.
- W4310567037 cites W3118245014 @default.
- W4310567037 cites W3158541100 @default.
- W4310567037 cites W3177149001 @default.
- W4310567037 cites W3181711150 @default.
- W4310567037 cites W3195968738 @default.
- W4310567037 cites W3210353759 @default.
- W4310567037 cites W4225993798 @default.
- W4310567037 cites W4226113914 @default.
- W4310567037 doi "https://doi.org/10.1002/pbc.30110" @default.
- W4310567037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36451260" @default.
- W4310567037 hasPublicationYear "2022" @default.
- W4310567037 type Work @default.