FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310570156> ?p ?o ?g. }

• W4310570156 endingPage "397" @default.
• W4310570156 startingPage "389" @default.
• W4310570156 abstract "<b><i>Objectives:</i></b> Ovarian cancer has the worst overall survival rate of all gynecologic malignancies. For the majority of patients, the 5-year overall survival rate of less than 50% has hardly improved over the last decades. To improve the outcome of patients with all subtypes of ovarian cancer, large-scale fundamental and translational research is needed. To accommodate these types of ovarian cancer research, we have established a Dutch nationwide, interdisciplinary infrastructure and biobank: the Archipelago of Ovarian Cancer Research (AOCR). The AOCR will facilitate fundamental and translational ovarian cancer research and enhance interdisciplinary, national, and international collaboration. <b><i>Design:</i></b> The AOCR biobank is a prospective ovarian cancer biobank in which biomaterials are collected, processed, and stored in a uniform matter for future (genetic) scientific research. All 19 Dutch hospitals in which ovarian cancer surgery is performed participate and collaborate in the AOCR biobank. <b><i>Participants/Materials, Setting, Methods:</i></b> Patients of 16 years and older with suspected or diagnosed ovarian, fallopian tube, or primary peritoneal cancer are recruited for participation. Patients who agree to participate give written informed consent for collection, storage, and issue of their biomaterials for future studies. After inclusion, different blood samples are taken at various predefined time points both before and during treatment. In case of a diagnostic paracentesis or biopsy, the residual biomaterials of these procedures are stored in the biobank. During surgery, primary tumor tissue and, if applicable, tissue from metastatic sites are collected and stored. From each patient, a representative histological hematoxylin and eosin stained slide is digitalized for research purposes, including reassessment by a panel of gynecologic pathologists. Clinical and pathological data are obtained on a per-study basis from Dutch registries. Research proposals for the issue of biomaterials and data are evaluated by both the Archipelago Scientific Committee and the Steering Committee. Researchers using the biomaterials from the AOCR biobank are encouraged to enrich the biobank with data and materials resulting from their analyses and experiments. <b><i>Limitations:</i></b> The implementation and first 4 years of collection are financed by an infrastructural grant from the Dutch Cancer Society. Therefore, the main limitation is that the costs for sustaining the biobank after the funding period will have to be covered. This coverage will come from incorporation of budget for biobanking in future grant applications and from fees from external researchers and commercial parties using the biomaterials stored in the AOCR biobank. Moreover, we will apply for grants aimed at sustaining and improving research infrastructures and biobanks. <b><i>Conclusions:</i></b> With the establishment of the Dutch nationwide, interdisciplinary Archipelago of Ovarian Cancer Research infrastructure and biobank, fundamental and translational research on ovarian cancer can be greatly improved. The ultimate aim of this infrastructure is that it will lead to improved diagnostics, treatment, and survival of patients with ovarian cancer." @default.
• W4310570156 created "2022-12-12" @default.
• W4310570156 creator A5000314896 @default.
• W4310570156 creator A5004064474 @default.
• W4310570156 creator A5004459794 @default.
• W4310570156 creator A5007843696 @default.
• W4310570156 creator A5014115556 @default.
• W4310570156 creator A5016742486 @default.
• W4310570156 creator A5018956853 @default.
• W4310570156 creator A5021158371 @default.
• W4310570156 creator A5024672374 @default.
• W4310570156 creator A5025523878 @default.
• W4310570156 creator A5028581150 @default.
• W4310570156 creator A5034667720 @default.
• W4310570156 creator A5038438236 @default.
• W4310570156 creator A5038936398 @default.
• W4310570156 creator A5043980504 @default.
• W4310570156 creator A5044831857 @default.
• W4310570156 creator A5045958709 @default.
• W4310570156 creator A5046086242 @default.
• W4310570156 creator A5046825294 @default.
• W4310570156 creator A5051795266 @default.
• W4310570156 creator A5059110184 @default.
• W4310570156 creator A5066451228 @default.
• W4310570156 creator A5066547884 @default.
• W4310570156 creator A5068372434 @default.
• W4310570156 creator A5068453772 @default.
• W4310570156 creator A5077700231 @default.
• W4310570156 creator A5085490585 @default.
• W4310570156 creator A5086897526 @default.
• W4310570156 creator A5087173779 @default.
• W4310570156 creator A5087805164 @default.
• W4310570156 date "2022-01-01" @default.
• W4310570156 modified "2023-10-16" @default.
• W4310570156 title "Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research" @default.
• W4310570156 doi "https://doi.org/10.1159/000528330" @default.
• W4310570156 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36450222" @default.
• W4310570156 hasPublicationYear "2022" @default.
• W4310570156 type Work @default.
• W4310570156 citedByCount "1" @default.
• W4310570156 countsByYear W43105701562023 @default.
• W4310570156 crossrefType "journal-article" @default.
• W4310570156 hasAuthorship W4310570156A5000314896 @default.
• W4310570156 hasAuthorship W4310570156A5004064474 @default.
• W4310570156 hasAuthorship W4310570156A5004459794 @default.
• W4310570156 hasAuthorship W4310570156A5007843696 @default.
• W4310570156 hasAuthorship W4310570156A5014115556 @default.
• W4310570156 hasAuthorship W4310570156A5016742486 @default.
• W4310570156 hasAuthorship W4310570156A5018956853 @default.
• W4310570156 hasAuthorship W4310570156A5021158371 @default.
• W4310570156 hasAuthorship W4310570156A5024672374 @default.
• W4310570156 hasAuthorship W4310570156A5025523878 @default.
• W4310570156 hasAuthorship W4310570156A5028581150 @default.
• W4310570156 hasAuthorship W4310570156A5034667720 @default.
• W4310570156 hasAuthorship W4310570156A5038438236 @default.
• W4310570156 hasAuthorship W4310570156A5038936398 @default.
• W4310570156 hasAuthorship W4310570156A5043980504 @default.
• W4310570156 hasAuthorship W4310570156A5044831857 @default.
• W4310570156 hasAuthorship W4310570156A5045958709 @default.
• W4310570156 hasAuthorship W4310570156A5046086242 @default.
• W4310570156 hasAuthorship W4310570156A5046825294 @default.
• W4310570156 hasAuthorship W4310570156A5051795266 @default.
• W4310570156 hasAuthorship W4310570156A5059110184 @default.
• W4310570156 hasAuthorship W4310570156A5066451228 @default.
• W4310570156 hasAuthorship W4310570156A5066547884 @default.
• W4310570156 hasAuthorship W4310570156A5068372434 @default.
• W4310570156 hasAuthorship W4310570156A5068453772 @default.
• W4310570156 hasAuthorship W4310570156A5077700231 @default.
• W4310570156 hasAuthorship W4310570156A5085490585 @default.
• W4310570156 hasAuthorship W4310570156A5086897526 @default.
• W4310570156 hasAuthorship W4310570156A5087173779 @default.
• W4310570156 hasAuthorship W4310570156A5087805164 @default.
• W4310570156 hasBestOaLocation W43105701561 @default.
• W4310570156 hasConcept C116567970 @default.
• W4310570156 hasConcept C121608353 @default.
• W4310570156 hasConcept C126322002 @default.
• W4310570156 hasConcept C128544194 @default.
• W4310570156 hasConcept C142724271 @default.
• W4310570156 hasConcept C143998085 @default.
• W4310570156 hasConcept C2780427987 @default.
• W4310570156 hasConcept C29456083 @default.
• W4310570156 hasConcept C60644358 @default.
• W4310570156 hasConcept C71924100 @default.
• W4310570156 hasConcept C86803240 @default.
• W4310570156 hasConceptScore W4310570156C116567970 @default.
• W4310570156 hasConceptScore W4310570156C121608353 @default.
• W4310570156 hasConceptScore W4310570156C126322002 @default.
• W4310570156 hasConceptScore W4310570156C128544194 @default.
• W4310570156 hasConceptScore W4310570156C142724271 @default.
• W4310570156 hasConceptScore W4310570156C143998085 @default.
• W4310570156 hasConceptScore W4310570156C2780427987 @default.
• W4310570156 hasConceptScore W4310570156C29456083 @default.
• W4310570156 hasConceptScore W4310570156C60644358 @default.
• W4310570156 hasConceptScore W4310570156C71924100 @default.
• W4310570156 hasConceptScore W4310570156C86803240 @default.
• W4310570156 hasIssue "6" @default.
• W4310570156 hasLocation W43105701561 @default.
• W4310570156 hasLocation W43105701562 @default.

• next