FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310573441> ?p ?o ?g. }

• W4310573441 endingPage "e273" @default.
• W4310573441 startingPage "e262" @default.
• W4310573441 abstract "Liquid chromatography coupled with mass spectrometry (LC-MS) has been increasingly used for screening purposes in forensic toxicology. High versatility and low time/resource consumption are the main advantages of this technology. Numerous multi-analyte methods have been validated in order to face the analytical challenge of new psychoactive substances (NPSs). However, forensic toxicologists must focus the attention also on classical NPSs and medicines, such as benzodiazepines (BDZs) and prescription opioids. In this paper, a new method for the simultaneous detection of 169 substances (120 NPSs and 49 other drugs) in hair by LC-MS-MS is described. After the decontamination of hair samples with dichloromethane, a 20-mg aliquot of the sample was mixed with 1 mL of methanol (MeOH; 0.1% of formic acid) and then sonicated at room temperature for 2 h. The mixture was then dried under nitrogen stream and reconstituted with 100 µL of MeOH. LC separation was achieved with a 100-mm-long C18 column in 35 min, and mass acquisition was performed in dynamic multiple reaction monitoring mode and in positive ionization. The analysis results were very sensitive, with the limit of quantification ranging from 0.07 to 10.0 pg/mg. Accuracy and precision were always within the acceptable criteria. Matrix effect and recovery rate ranges were from -21.3 to + 21.9% and from 75.0 to 99.3%, respectively. The new method was successfully applied in a preliminary study on the prevalence of NPSs, BDZs and other substances in case of driving license issuance. In 14% of cases, BDZs/antidepressants (mainly trazodone, diazepam/nordiazepam and flunitrazepam) were found. Codeine, ketamine, methylone and mephedrone were also detected." @default.
• W4310573441 created "2022-12-12" @default.
• W4310573441 creator A5015954209 @default.
• W4310573441 creator A5033220996 @default.
• W4310573441 creator A5034396954 @default.
• W4310573441 creator A5041473997 @default.
• W4310573441 creator A5048595802 @default.
• W4310573441 creator A5059959649 @default.
• W4310573441 creator A5071719739 @default.
• W4310573441 creator A5083460461 @default.
• W4310573441 creator A5091283776 @default.
• W4310573441 date "2022-11-01" @default.
• W4310573441 modified "2023-10-01" @default.
• W4310573441 title "A New Multi-Analyte LC–MS-MS Screening Method for the Detection of 120 NPSs and 49 Drugs in Hair" @default.
• W4310573441 cites W1548435921 @default.
• W4310573441 cites W1596985037 @default.
• W4310573441 cites W1970339848 @default.
• W4310573441 cites W1979990272 @default.
• W4310573441 cites W1981914470 @default.
• W4310573441 cites W2001432313 @default.
• W4310573441 cites W2001989093 @default.
• W4310573441 cites W2012398785 @default.
• W4310573441 cites W2080558665 @default.
• W4310573441 cites W2092046290 @default.
• W4310573441 cites W2141965408 @default.
• W4310573441 cites W2150259429 @default.
• W4310573441 cites W2154718865 @default.
• W4310573441 cites W2154847791 @default.
• W4310573441 cites W2159137251 @default.
• W4310573441 cites W2169064904 @default.
• W4310573441 cites W2238692515 @default.
• W4310573441 cites W2292615329 @default.
• W4310573441 cites W2322504283 @default.
• W4310573441 cites W2342836479 @default.
• W4310573441 cites W2469555020 @default.
• W4310573441 cites W2491709792 @default.
• W4310573441 cites W2507307736 @default.
• W4310573441 cites W2512201793 @default.
• W4310573441 cites W2648308082 @default.
• W4310573441 cites W2693036711 @default.
• W4310573441 cites W2746295609 @default.
• W4310573441 cites W2750882669 @default.
• W4310573441 cites W2756110104 @default.
• W4310573441 cites W2773032125 @default.
• W4310573441 cites W2786430007 @default.
• W4310573441 cites W2889008119 @default.
• W4310573441 cites W2941827532 @default.
• W4310573441 cites W2944251535 @default.
• W4310573441 cites W2995593754 @default.
• W4310573441 cites W3005282593 @default.
• W4310573441 cites W3006170050 @default.
• W4310573441 cites W3008467564 @default.
• W4310573441 cites W3043733336 @default.
• W4310573441 cites W3092635370 @default.
• W4310573441 cites W3093333922 @default.
• W4310573441 cites W3100749967 @default.
• W4310573441 cites W3152960166 @default.
• W4310573441 cites W3175004491 @default.
• W4310573441 cites W3185030705 @default.
• W4310573441 cites W3192350378 @default.
• W4310573441 cites W3203138150 @default.
• W4310573441 cites W3205359493 @default.
• W4310573441 cites W3211405387 @default.
• W4310573441 cites W4200525402 @default.
• W4310573441 cites W4254185355 @default.
• W4310573441 doi "https://doi.org/10.1093/jat/bkac093" @default.
• W4310573441 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36453750" @default.
• W4310573441 hasPublicationYear "2022" @default.
• W4310573441 type Work @default.
• W4310573441 citedByCount "3" @default.
• W4310573441 countsByYear W43105734412023 @default.
• W4310573441 crossrefType "journal-article" @default.
• W4310573441 hasAuthorship W4310573441A5015954209 @default.
• W4310573441 hasAuthorship W4310573441A5033220996 @default.
• W4310573441 hasAuthorship W4310573441A5034396954 @default.
• W4310573441 hasAuthorship W4310573441A5041473997 @default.
• W4310573441 hasAuthorship W4310573441A5048595802 @default.
• W4310573441 hasAuthorship W4310573441A5059959649 @default.
• W4310573441 hasAuthorship W4310573441A5071719739 @default.
• W4310573441 hasAuthorship W4310573441A5083460461 @default.
• W4310573441 hasAuthorship W4310573441A5091283776 @default.
• W4310573441 hasConcept C10390740 @default.
• W4310573441 hasConcept C119128265 @default.
• W4310573441 hasConcept C162356407 @default.
• W4310573441 hasConcept C185592680 @default.
• W4310573441 hasConcept C2777379063 @default.
• W4310573441 hasConcept C43617362 @default.
• W4310573441 hasConcept C64489805 @default.
• W4310573441 hasConceptScore W4310573441C10390740 @default.
• W4310573441 hasConceptScore W4310573441C119128265 @default.
• W4310573441 hasConceptScore W4310573441C162356407 @default.
• W4310573441 hasConceptScore W4310573441C185592680 @default.
• W4310573441 hasConceptScore W4310573441C2777379063 @default.
• W4310573441 hasConceptScore W4310573441C43617362 @default.
• W4310573441 hasConceptScore W4310573441C64489805 @default.
• W4310573441 hasIssue "9" @default.
• W4310573441 hasLocation W43105734411 @default.
• W4310573441 hasLocation W43105734412 @default.

• next