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• W4310591317 abstract "Nuclear receptors are ligand-dependent transcription factors that act as signal transducers by binding to and regulating the transcription of target DNA (genomic action). In recent years, nuclear receptors have also been found to exhibit a direct action on target proteins without affecting their transcription (non-genomic action). Independent complexes are expected to distinguish these two nuclear receptor actions. In this paper, I report the non-genomic action of peroxisome proliferator-activated receptor γ (PPARγ) agonists and propose a strategy for treatment of renal fibrotic diseases by PPARγ agonists with an emphasis on non-genomic actions." @default.
• W4310591317 created "2022-12-12" @default.
• W4310591317 creator A5011433902 @default.
• W4310591317 date "2022-12-01" @default.
• W4310591317 modified "2023-10-18" @default.
• W4310591317 title "Attempt to Create a Drug for Treatment of Fibrotic Diseases Based on the Non-genomic Action of Nuclear Receptors" @default.
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• W4310591317 doi "https://doi.org/10.1248/yakushi.22-00159-4" @default.
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