Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310593273> ?p ?o ?g. }
Showing items 1 to 67 of
67
with 100 items per page.
- W4310593273 endingPage "1756" @default.
- W4310593273 startingPage "1748" @default.
- W4310593273 abstract "Introduction: The broth microdilution (BMD) method recommended for the detection of colistin resistance is labor-intensive, time-consuming, and difficult to apply in routine laboratories. Thus, various methods, such as disk elution, commercial microdilution, and rapid polymyxin-NP tests have been developed for the detection of colistin resistance. In this study, a total of 102 multi-resistant Gram-negative bacteria isolated from blood cultures were evaluated by four different methods for the detection of colistin resistance, and compared with the reference method.
 Methodology: For the detection of the compatibility of these methods with the reference method, categorical and essential agreements, very major, major, and minor error rates were determined. Colistin-tigecycline and colistin-meropenem combinations were investigated in colistin-resistant isolates.
 Results: Of the isolates, 15 (15%) [K. pneumoniae (n = 12), A. baumannii (n = 2), E. coli (n = 1)] were resistant to colistin with reference BMD method. MIC50 and MIC90 values of all isolates were ≤ 0.25 μg/mL and 16 μg/mL, respectively. The categorical agreement rates were 100% for commercial microdilution, disk elution, and RPNP test. The essential agreement rates of commercial microdilution, disk elution, and broth macrodilution were 78.4%, 86.3%, and 100%, respectively. Although there were no major errors in these methods, the macrodilution (12%) and commercial microdilution (20.6%) methods showed the most minor errors. Colistin-meropenem combination showed a 100% synergistic effect, but the colistin-tigecycline combination showed an 80% synergistic effect and 20% indifference effect.
 Conclusions: Disk elution and RPNP tests are suitable for routine use because they are the most efficient, easiest, low-cost, and good performance tests in detecting colistin resistance." @default.
- W4310593273 created "2022-12-12" @default.
- W4310593273 creator A5045558042 @default.
- W4310593273 creator A5051244685 @default.
- W4310593273 date "2022-11-29" @default.
- W4310593273 modified "2023-09-26" @default.
- W4310593273 title "Detection of colistin resistance via four methods in multidrug-resistant Gram-negative rods isolated from blood cultures" @default.
- W4310593273 doi "https://doi.org/10.3855/jidc.16480" @default.
- W4310593273 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36449647" @default.
- W4310593273 hasPublicationYear "2022" @default.
- W4310593273 type Work @default.
- W4310593273 citedByCount "0" @default.
- W4310593273 crossrefType "journal-article" @default.
- W4310593273 hasAuthorship W4310593273A5045558042 @default.
- W4310593273 hasAuthorship W4310593273A5051244685 @default.
- W4310593273 hasBestOaLocation W43105932731 @default.
- W4310593273 hasConcept C176947019 @default.
- W4310593273 hasConcept C2776315533 @default.
- W4310593273 hasConcept C2777027569 @default.
- W4310593273 hasConcept C2777637488 @default.
- W4310593273 hasConcept C2779259085 @default.
- W4310593273 hasConcept C2779375183 @default.
- W4310593273 hasConcept C2780675486 @default.
- W4310593273 hasConcept C2780950330 @default.
- W4310593273 hasConcept C4937899 @default.
- W4310593273 hasConcept C501593827 @default.
- W4310593273 hasConcept C523546767 @default.
- W4310593273 hasConcept C54355233 @default.
- W4310593273 hasConcept C86803240 @default.
- W4310593273 hasConcept C89423630 @default.
- W4310593273 hasConcept C94665300 @default.
- W4310593273 hasConceptScore W4310593273C176947019 @default.
- W4310593273 hasConceptScore W4310593273C2776315533 @default.
- W4310593273 hasConceptScore W4310593273C2777027569 @default.
- W4310593273 hasConceptScore W4310593273C2777637488 @default.
- W4310593273 hasConceptScore W4310593273C2779259085 @default.
- W4310593273 hasConceptScore W4310593273C2779375183 @default.
- W4310593273 hasConceptScore W4310593273C2780675486 @default.
- W4310593273 hasConceptScore W4310593273C2780950330 @default.
- W4310593273 hasConceptScore W4310593273C4937899 @default.
- W4310593273 hasConceptScore W4310593273C501593827 @default.
- W4310593273 hasConceptScore W4310593273C523546767 @default.
- W4310593273 hasConceptScore W4310593273C54355233 @default.
- W4310593273 hasConceptScore W4310593273C86803240 @default.
- W4310593273 hasConceptScore W4310593273C89423630 @default.
- W4310593273 hasConceptScore W4310593273C94665300 @default.
- W4310593273 hasIssue "11" @default.
- W4310593273 hasLocation W43105932731 @default.
- W4310593273 hasLocation W43105932732 @default.
- W4310593273 hasOpenAccess W4310593273 @default.
- W4310593273 hasPrimaryLocation W43105932731 @default.
- W4310593273 hasRelatedWork W1963667269 @default.
- W4310593273 hasRelatedWork W2579017850 @default.
- W4310593273 hasRelatedWork W2982009869 @default.
- W4310593273 hasRelatedWork W3135904606 @default.
- W4310593273 hasRelatedWork W3194605897 @default.
- W4310593273 hasRelatedWork W4200023422 @default.
- W4310593273 hasRelatedWork W4229370529 @default.
- W4310593273 hasRelatedWork W4291021403 @default.
- W4310593273 hasRelatedWork W4313531458 @default.
- W4310593273 hasRelatedWork W1937173723 @default.
- W4310593273 hasVolume "16" @default.
- W4310593273 isParatext "false" @default.
- W4310593273 isRetracted "false" @default.
- W4310593273 workType "article" @default.