FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310593399> ?p ?o ?g. }

• W4310593399 abstract "Abstract Background Tumors develop within an organism operating in a specific social and physical environment. Cortisol and dehydroepiandrosterone (DHEA), two of the most abundant steroid hormones in humans, are involved in both emotional regulation and the tumor progression. Several studies reported preclinical findings that DHEA can have preventive and therapeutic efficacy in treating major age-associated diseases, including cancer, although the mechanisms of action are not yet defined. The main aim of current study was to investigate the relationship between psychological and physiological emotional regulation and cancer development. Method This study assessed the quality of life of urogenital cancer male patients using several validated tools, including the Functional Assessment of Cancer Therapy-General and the Profile of Mood States. Saliva samples were collected to monitor peripheral activity of both cortisol and DHEA. It was hypothesized that patients with a better quality of life would have higher levels of the DHEA/cortisol ratios. Results We found that the quality of life was positively related to DHEA, but not cortisol levels. Negative mood increases were related to lower levels of DHEA. Logistic regression of the predictors of metastases indicated three main independent factors involved: DHEA, age, and cortisol. In other words, the higher the DHEA levels in comparison to cortisol levels, controlling for age, the lower the probability of metastases. Conclusion Our results appear to support the hypothesis that emotional dysregulation mediated by DHEA/cortisol activity is a key factor in the probability of metastasis in urogenital cancers." @default.
• W4310593399 created "2022-12-12" @default.
• W4310593399 creator A5017051324 @default.
• W4310593399 creator A5027682826 @default.
• W4310593399 creator A5029935476 @default.
• W4310593399 creator A5033363033 @default.
• W4310593399 creator A5036453124 @default.
• W4310593399 creator A5045594092 @default.
• W4310593399 creator A5050042779 @default.
• W4310593399 creator A5050526064 @default.
• W4310593399 creator A5063192686 @default.
• W4310593399 creator A5073855641 @default.
• W4310593399 creator A5081442048 @default.
• W4310593399 creator A5086287436 @default.
• W4310593399 date "2022-12-02" @default.
• W4310593399 modified "2023-09-26" @default.
• W4310593399 title "Steroid Hormones as Modulators of Emotional Regulation in Male Urogenital Cancers" @default.
• W4310593399 cites W1859979612 @default.
• W4310593399 cites W1981748148 @default.
• W4310593399 cites W1983091382 @default.
• W4310593399 cites W1989396540 @default.
• W4310593399 cites W1993202266 @default.
• W4310593399 cites W1999958249 @default.
• W4310593399 cites W2000806250 @default.
• W4310593399 cites W2008950282 @default.
• W4310593399 cites W2019716845 @default.
• W4310593399 cites W2020569322 @default.
• W4310593399 cites W2021277514 @default.
• W4310593399 cites W2037707039 @default.
• W4310593399 cites W2038803905 @default.
• W4310593399 cites W2039935280 @default.
• W4310593399 cites W2042430625 @default.
• W4310593399 cites W2045472160 @default.
• W4310593399 cites W2067733496 @default.
• W4310593399 cites W2068958502 @default.
• W4310593399 cites W2076874338 @default.
• W4310593399 cites W2091366037 @default.
• W4310593399 cites W2105258029 @default.
• W4310593399 cites W2116456368 @default.
• W4310593399 cites W2117309811 @default.
• W4310593399 cites W2117692326 @default.
• W4310593399 cites W2117854292 @default.
• W4310593399 cites W2119315696 @default.
• W4310593399 cites W2122080204 @default.
• W4310593399 cites W2130198046 @default.
• W4310593399 cites W2131832357 @default.
• W4310593399 cites W2134509878 @default.
• W4310593399 cites W2157098119 @default.
• W4310593399 cites W2462347288 @default.
• W4310593399 cites W2494134352 @default.
• W4310593399 cites W2672668855 @default.
• W4310593399 cites W2783442236 @default.
• W4310593399 cites W2793363299 @default.
• W4310593399 cites W2793979883 @default.
• W4310593399 cites W2794300276 @default.
• W4310593399 cites W2795684537 @default.
• W4310593399 cites W2799823550 @default.
• W4310593399 cites W2887742757 @default.
• W4310593399 cites W2912992939 @default.
• W4310593399 cites W2917837889 @default.
• W4310593399 cites W2923966553 @default.
• W4310593399 cites W2943789716 @default.
• W4310593399 cites W2949296595 @default.
• W4310593399 cites W2974805241 @default.
• W4310593399 cites W2982485778 @default.
• W4310593399 cites W2992822490 @default.
• W4310593399 cites W3012408003 @default.
• W4310593399 cites W3024476737 @default.
• W4310593399 cites W3025805927 @default.
• W4310593399 cites W3047397691 @default.
• W4310593399 cites W3097435576 @default.
• W4310593399 cites W3097662568 @default.
• W4310593399 cites W4226051756 @default.
• W4310593399 cites W4229378068 @default.
• W4310593399 cites W4230475087 @default.
• W4310593399 cites W4322695807 @default.
• W4310593399 doi "https://doi.org/10.1007/s12529-022-10139-w" @default.
• W4310593399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36459332" @default.
• W4310593399 hasPublicationYear "2022" @default.
• W4310593399 type Work @default.
• W4310593399 citedByCount "0" @default.
• W4310593399 crossrefType "journal-article" @default.
• W4310593399 hasAuthorship W4310593399A5017051324 @default.
• W4310593399 hasAuthorship W4310593399A5027682826 @default.
• W4310593399 hasAuthorship W4310593399A5029935476 @default.
• W4310593399 hasAuthorship W4310593399A5033363033 @default.
• W4310593399 hasAuthorship W4310593399A5036453124 @default.
• W4310593399 hasAuthorship W4310593399A5045594092 @default.
• W4310593399 hasAuthorship W4310593399A5050042779 @default.
• W4310593399 hasAuthorship W4310593399A5050526064 @default.
• W4310593399 hasAuthorship W4310593399A5063192686 @default.
• W4310593399 hasAuthorship W4310593399A5073855641 @default.
• W4310593399 hasAuthorship W4310593399A5081442048 @default.
• W4310593399 hasAuthorship W4310593399A5086287436 @default.
• W4310593399 hasBestOaLocation W43105933991 @default.
• W4310593399 hasConcept C121608353 @default.
• W4310593399 hasConcept C126322002 @default.
• W4310593399 hasConcept C133507102 @default.
• W4310593399 hasConcept C134018914 @default.
• W4310593399 hasConcept C143998085 @default.

• next