Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310596104> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4310596104 endingPage "789" @default.
- W4310596104 startingPage "787" @default.
- W4310596104 abstract "Tamoxifen, the prototypic medication for breast cancer prevention, was approved for this purpose by the FDA in 1998. Other drugs have been proven to be effective in the ensuing decades. But the two major limitations of these have become clear over time: a lack of protection against hormone receptor–negative breast cancer, and a profile of safety and tolerability that is unacceptable to the majority of women at increased breast cancer risk. Recent preclinical data on targeting of the key oncogenic pathway of PI3K/AKT/mTOR signaling with drugs such as rapamycin and everolimus are provocative. Their efficacy signal should be pursued with further research, but their safety and tolerability profiles remain a concern. See related article by Mazumdar et al., p. 791" @default.
- W4310596104 created "2022-12-12" @default.
- W4310596104 creator A5001281713 @default.
- W4310596104 creator A5075214231 @default.
- W4310596104 date "2022-12-01" @default.
- W4310596104 modified "2023-09-30" @default.
- W4310596104 title "Everolimus for Estrogen Receptor–negative Breast Cancer Prevention: A Journey Begun?" @default.
- W4310596104 cites W1966623655 @default.
- W4310596104 cites W2026659511 @default.
- W4310596104 cites W2080947811 @default.
- W4310596104 cites W2104479370 @default.
- W4310596104 cites W2105442326 @default.
- W4310596104 cites W2106885203 @default.
- W4310596104 cites W2121917721 @default.
- W4310596104 cites W2159890963 @default.
- W4310596104 cites W2161387798 @default.
- W4310596104 cites W2168414916 @default.
- W4310596104 cites W2195518879 @default.
- W4310596104 cites W2263386431 @default.
- W4310596104 cites W2806592404 @default.
- W4310596104 cites W2938233323 @default.
- W4310596104 cites W2995994771 @default.
- W4310596104 doi "https://doi.org/10.1158/1940-6207.capr-22-0419" @default.
- W4310596104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36453053" @default.
- W4310596104 hasPublicationYear "2022" @default.
- W4310596104 type Work @default.
- W4310596104 citedByCount "0" @default.
- W4310596104 crossrefType "journal-article" @default.
- W4310596104 hasAuthorship W4310596104A5001281713 @default.
- W4310596104 hasAuthorship W4310596104A5075214231 @default.
- W4310596104 hasConcept C121608353 @default.
- W4310596104 hasConcept C126322002 @default.
- W4310596104 hasConcept C143998085 @default.
- W4310596104 hasConcept C197934379 @default.
- W4310596104 hasConcept C2777176818 @default.
- W4310596104 hasConcept C2777944059 @default.
- W4310596104 hasConcept C2778375690 @default.
- W4310596104 hasConcept C2779699572 @default.
- W4310596104 hasConcept C530470458 @default.
- W4310596104 hasConcept C55493867 @default.
- W4310596104 hasConcept C62478195 @default.
- W4310596104 hasConcept C71924100 @default.
- W4310596104 hasConcept C84606932 @default.
- W4310596104 hasConcept C86554907 @default.
- W4310596104 hasConcept C86803240 @default.
- W4310596104 hasConcept C98274493 @default.
- W4310596104 hasConceptScore W4310596104C121608353 @default.
- W4310596104 hasConceptScore W4310596104C126322002 @default.
- W4310596104 hasConceptScore W4310596104C143998085 @default.
- W4310596104 hasConceptScore W4310596104C197934379 @default.
- W4310596104 hasConceptScore W4310596104C2777176818 @default.
- W4310596104 hasConceptScore W4310596104C2777944059 @default.
- W4310596104 hasConceptScore W4310596104C2778375690 @default.
- W4310596104 hasConceptScore W4310596104C2779699572 @default.
- W4310596104 hasConceptScore W4310596104C530470458 @default.
- W4310596104 hasConceptScore W4310596104C55493867 @default.
- W4310596104 hasConceptScore W4310596104C62478195 @default.
- W4310596104 hasConceptScore W4310596104C71924100 @default.
- W4310596104 hasConceptScore W4310596104C84606932 @default.
- W4310596104 hasConceptScore W4310596104C86554907 @default.
- W4310596104 hasConceptScore W4310596104C86803240 @default.
- W4310596104 hasConceptScore W4310596104C98274493 @default.
- W4310596104 hasIssue "12" @default.
- W4310596104 hasLocation W43105961041 @default.
- W4310596104 hasLocation W43105961042 @default.
- W4310596104 hasOpenAccess W4310596104 @default.
- W4310596104 hasPrimaryLocation W43105961041 @default.
- W4310596104 hasRelatedWork W1997973482 @default.
- W4310596104 hasRelatedWork W2061974211 @default.
- W4310596104 hasRelatedWork W2099493846 @default.
- W4310596104 hasRelatedWork W2103643613 @default.
- W4310596104 hasRelatedWork W2336263598 @default.
- W4310596104 hasRelatedWork W2403618362 @default.
- W4310596104 hasRelatedWork W2496465202 @default.
- W4310596104 hasRelatedWork W2776121059 @default.
- W4310596104 hasRelatedWork W4309488699 @default.
- W4310596104 hasRelatedWork W2309772632 @default.
- W4310596104 hasVolume "15" @default.
- W4310596104 isParatext "false" @default.
- W4310596104 isRetracted "false" @default.
- W4310596104 workType "article" @default.