FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310597858> ?p ?o ?g. }

• W4310597858 endingPage "282" @default.
• W4310597858 startingPage "270" @default.
• W4310597858 abstract "This study investigated the relationship between nutritional status, as determined by the prognostic nutritional index (PNI), and outcomes in patients with unresectable hepatocellular carcinoma (HCC) treated with atezolizumab plus bevacizumab (Atez/bev).The study analyzed 485 HCC patients treated with Atez/bev.There were 342 patients with a low PNI (<47) and 143 patients with a high PNI (≥47). The median follow-up duration was 9.4 (6.0-14.3) months. Multivariate Cox hazards analysis showed that an α-fetoprotein level ≥100 ng/mL (hazard ratio (HR), 2.217; 95% confidence interval (CI), 1.588-3.095; p < 0.001), and PNI ≥47 (HR, 0.333; 95% CI, 0.212-0.525; p < 0.001) were independently associated with overall survival. Multivariate analysis showed that an α-fetoprotein level ≥100 ng/mL (HR, 1.690; 95% CI, 1.316-2.170; p < 0.001) and PNI ≥47 (HR, 0.696; 95% CI, 0.528-0.918; p = 0.010) were independently associated with progression-free survival. Cumulative overall and progression-free survival rates differed significantly by PNI (p < 0.001 and p < 0.002, respectively). In a subgroup analysis using inverse probability weighting adjustment in patients with albumin-bilirubin grade 1 (n = 173), univariate Cox hazards analysis showed that a PNI ≥47 (HR, 0.502; 95% CI, 0.260-0.991; p = 0.047) was significantly associated with overall survival. Spline curve analysis revealed that a PNI of approximately 34-48 is an appropriate cutoff for predicting good overall and progression-free survival.The PNI, a biomarker of nutritional status, can predict prognosis in patients with HCC treated with Atez/bev, even those who are considered to have a good prognosis due to good liver function." @default.
• W4310597858 created "2022-12-12" @default.
• W4310597858 creator A5002259532 @default.
• W4310597858 creator A5007665821 @default.
• W4310597858 creator A5008593372 @default.
• W4310597858 creator A5009103376 @default.
• W4310597858 creator A5013902375 @default.
• W4310597858 creator A5015404124 @default.
• W4310597858 creator A5015534419 @default.
• W4310597858 creator A5015651545 @default.
• W4310597858 creator A5017999006 @default.
• W4310597858 creator A5020047441 @default.
• W4310597858 creator A5022551435 @default.
• W4310597858 creator A5023981784 @default.
• W4310597858 creator A5025980433 @default.
• W4310597858 creator A5026964230 @default.
• W4310597858 creator A5028697785 @default.
• W4310597858 creator A5030286729 @default.
• W4310597858 creator A5035134420 @default.
• W4310597858 creator A5035561731 @default.
• W4310597858 creator A5040485741 @default.
• W4310597858 creator A5043762552 @default.
• W4310597858 creator A5047345098 @default.
• W4310597858 creator A5049568375 @default.
• W4310597858 creator A5050706722 @default.
• W4310597858 creator A5051182745 @default.
• W4310597858 creator A5053874442 @default.
• W4310597858 creator A5059536902 @default.
• W4310597858 creator A5064418329 @default.
• W4310597858 creator A5064709438 @default.
• W4310597858 creator A5066413780 @default.
• W4310597858 creator A5068214058 @default.
• W4310597858 creator A5072760293 @default.
• W4310597858 creator A5073095975 @default.
• W4310597858 creator A5078450345 @default.
• W4310597858 creator A5080709934 @default.
• W4310597858 creator A5083997418 @default.
• W4310597858 creator A5085648916 @default.
• W4310597858 creator A5085777607 @default.
• W4310597858 creator A5088307695 @default.
• W4310597858 creator A5090570708 @default.
• W4310597858 creator A5090674063 @default.
• W4310597858 date "2022-12-01" @default.
• W4310597858 modified "2023-10-13" @default.
• W4310597858 title "Nutritional Status Is Associated with Prognosis in Patients with Advanced Unresectable Hepatocellular Carcinoma Treated with Atezolizumab plus Bevacizumab" @default.
• W4310597858 doi "https://doi.org/10.1159/000527676" @default.
• W4310597858 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36455517" @default.
• W4310597858 hasPublicationYear "2022" @default.
• W4310597858 type Work @default.
• W4310597858 citedByCount "4" @default.
• W4310597858 countsByYear W43105978582023 @default.
• W4310597858 crossrefType "journal-article" @default.
• W4310597858 hasAuthorship W4310597858A5002259532 @default.
• W4310597858 hasAuthorship W4310597858A5007665821 @default.
• W4310597858 hasAuthorship W4310597858A5008593372 @default.
• W4310597858 hasAuthorship W4310597858A5009103376 @default.
• W4310597858 hasAuthorship W4310597858A5013902375 @default.
• W4310597858 hasAuthorship W4310597858A5015404124 @default.
• W4310597858 hasAuthorship W4310597858A5015534419 @default.
• W4310597858 hasAuthorship W4310597858A5015651545 @default.
• W4310597858 hasAuthorship W4310597858A5017999006 @default.
• W4310597858 hasAuthorship W4310597858A5020047441 @default.
• W4310597858 hasAuthorship W4310597858A5022551435 @default.
• W4310597858 hasAuthorship W4310597858A5023981784 @default.
• W4310597858 hasAuthorship W4310597858A5025980433 @default.
• W4310597858 hasAuthorship W4310597858A5026964230 @default.
• W4310597858 hasAuthorship W4310597858A5028697785 @default.
• W4310597858 hasAuthorship W4310597858A5030286729 @default.
• W4310597858 hasAuthorship W4310597858A5035134420 @default.
• W4310597858 hasAuthorship W4310597858A5035561731 @default.
• W4310597858 hasAuthorship W4310597858A5040485741 @default.
• W4310597858 hasAuthorship W4310597858A5043762552 @default.
• W4310597858 hasAuthorship W4310597858A5047345098 @default.
• W4310597858 hasAuthorship W4310597858A5049568375 @default.
• W4310597858 hasAuthorship W4310597858A5050706722 @default.
• W4310597858 hasAuthorship W4310597858A5051182745 @default.
• W4310597858 hasAuthorship W4310597858A5053874442 @default.
• W4310597858 hasAuthorship W4310597858A5059536902 @default.
• W4310597858 hasAuthorship W4310597858A5064418329 @default.
• W4310597858 hasAuthorship W4310597858A5064709438 @default.
• W4310597858 hasAuthorship W4310597858A5066413780 @default.
• W4310597858 hasAuthorship W4310597858A5068214058 @default.
• W4310597858 hasAuthorship W4310597858A5072760293 @default.
• W4310597858 hasAuthorship W4310597858A5073095975 @default.
• W4310597858 hasAuthorship W4310597858A5078450345 @default.
• W4310597858 hasAuthorship W4310597858A5080709934 @default.
• W4310597858 hasAuthorship W4310597858A5083997418 @default.
• W4310597858 hasAuthorship W4310597858A5085648916 @default.
• W4310597858 hasAuthorship W4310597858A5085777607 @default.
• W4310597858 hasAuthorship W4310597858A5088307695 @default.
• W4310597858 hasAuthorship W4310597858A5090570708 @default.
• W4310597858 hasAuthorship W4310597858A5090674063 @default.
• W4310597858 hasConcept C126322002 @default.
• W4310597858 hasConcept C143998085 @default.
• W4310597858 hasConcept C144301174 @default.
• W4310597858 hasConcept C207103383 @default.
• W4310597858 hasConcept C2776694085 @default.
• W4310597858 hasConcept C2777802072 @default.

• next