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• W4310658 abstract "PURPOSE: To study the 360-degree barrier effect of an intraocular lens (IOL) with a square edge at the optic and an enhanced square edge at the optic–haptic junctions (Rayner 570C C-flex) on centripetal migration of lens epithelial cells (LECs) over a 2-year period. SETTING: Department of Ophthalmology, Scarborough Hospital, Scarborough, United Kingdom. METHODS: In a prospective study of 40 consecutive eyes, a C-flex IOL was implanted in the bag after phacoemulsification surgery. Eyes with intraoperative complications, requiring additional procedures, without 360-degree overlap of the optic, or with capsule block syndrome were excluded. Follow-up was at 6, 10, 18, and 24 months. At each visit, high-magnification retroillumination digital photographs were taken using a slitlamp-attached digital camera. The barrier effect to LEC migration across the optic edge and the enhanced square edge at the optic–haptic junction was graded as complete (no epithelial pearls or sheet), partial (few epithelial pearls without sheet), and minimal/none (epithelial sheet behind the IOL optic). RESULTS: Twenty-four patients came to the final follow-up at 24 months. Fifteen of these eyes (63%) had a complete barrier effect throughout the 360 degrees of the IOL. Three eyes (13%) had a partial barrier effect throughout the 360 degrees of the IOL. Three eyes had a complete optic barrier effect but a partial optic–haptic junction barrier effect. Three eyes had a partial optic barrier effect but a complete optic–haptic junction barrier effect. No eye had epithelial sheets extending behind the optic at any location. CONCLUSIONS: This study showed the barrier effect of the edge design of the C-flex IOL and the efficacy of the enhanced edge in preventing LEC migration at the optic–haptic junction. The enhanced edge was as effective as a sharp square edge in restricting the LEC migration." @default.
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• W4310658 date "2007-01-01" @default.
• W4310658 modified "2023-10-16" @default.
• W4310658 title "Three-hundred-sixty degree barrier effect of a square-edged and an enhanced-edge intraocular lens on centripetal lens epithelial cell migration" @default.
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• W4310658 doi "https://doi.org/10.1016/j.jcrs.2006.08.048" @default.
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