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- W4310672810 abstract "The cyclic GMP-AMP synthase-stimulator of interferon genes signal transduction pathway is critical in innate immunity, infection, and inflammation. In response to pathogenic microbial infections and other conditions, cyclic GMP-AMP synthase (cGAS) recognizes abnormal DNA and initiates a downstream type I interferon response. This paper reviews the pathogenic mechanisms of stimulator of interferon genes (STING) in different organs, including changes in fibrosis-related biomarkers, intending to systematically investigate the effect of the cyclic GMP-AMP synthase-stimulator of interferon genes signal transduction in inflammation and fibrosis processes. The effects of stimulator of interferon genes in related auto-inflammatory and neurodegenerative diseases are described in this article, in addition to the application of stimulator of interferon genes-related drugs in treating fibrosis." @default.
- W4310672810 created "2022-12-15" @default.
- W4310672810 creator A5009596514 @default.
- W4310672810 creator A5032447166 @default.
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- W4310672810 creator A5036428356 @default.
- W4310672810 creator A5042332666 @default.
- W4310672810 creator A5045160787 @default.
- W4310672810 creator A5050395333 @default.
- W4310672810 creator A5063234446 @default.
- W4310672810 creator A5090210582 @default.
- W4310672810 date "2022-12-05" @default.
- W4310672810 modified "2023-10-16" @default.
- W4310672810 title "The effect of the cyclic GMP-AMP synthase-stimulator of interferon genes signaling pathway on organ inflammatory injury and fibrosis" @default.
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