Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310713029> ?p ?o ?g. }
- W4310713029 endingPage "112092" @default.
- W4310713029 startingPage "112092" @default.
- W4310713029 abstract "This study explores the effect of a thione/selone ligand on the cell toxicity (in vitro) and light activity of diimine Re(CO)3+ complexes. Six rhenium(I) complexes with general formula fac-[Re(CO)3(N,N′)X]+ were prepared, where X = 2-mercapto-1-methylimidazole (methimazole; MMI), and 1-methylimidazole-2-selone (MSeI); N,N′ = 2,2′-bipyridine (bpy), 1,10-phenanthroline (phen) and 2,9-dimethyl-1,10-phenanthroline (dmphen). Their triflate salts were characterized using single-crystal X-ray diffraction, 1H, 13C and 2D NMR, UV–vis and vibrational spectroscopy. Their cytotoxic properties were tested, showing significant cytotoxicity (IC50 = 8.0–55 μM) towards the human breast cancer cell line MDA-MB-231. The half-inhibitory concentration (IC50) for fac-[Re(CO)3(dmphen)(MMI)]+, the most toxic complex in this series (8.0 ± 0.2 μM), was comparable to that of the corresponding aqua complex fac-[Re(CO)3(dmphen)(H2O)]+ with IC50 = 6.0 ± 0.1 μM. The fac-[Re(CO)3(bpy)(MMI/MSeI)]+ complexes were somewhat less toxic towards the human embryonic kidney cell line HEK-293 T after 48 h of exposure. The stability of the complexes upon irradiation was monitored using UV–vis spectroscopy, with no CO released when exposed to UV-A light (λ = 365 nm)." @default.
- W4310713029 created "2022-12-16" @default.
- W4310713029 creator A5012075948 @default.
- W4310713029 creator A5012803164 @default.
- W4310713029 creator A5013092722 @default.
- W4310713029 creator A5023660955 @default.
- W4310713029 creator A5031516890 @default.
- W4310713029 creator A5064019950 @default.
- W4310713029 creator A5081285582 @default.
- W4310713029 date "2023-03-01" @default.
- W4310713029 modified "2023-09-23" @default.
- W4310713029 title "Rhenium(I)-tricarbonyl complexes with methimazole and its selenium analogue: Syntheses, characterization and cell toxicity" @default.
- W4310713029 cites W1516330225 @default.
- W4310713029 cites W1958115098 @default.
- W4310713029 cites W1969360633 @default.
- W4310713029 cites W1983589290 @default.
- W4310713029 cites W1987381030 @default.
- W4310713029 cites W1993333727 @default.
- W4310713029 cites W1994531489 @default.
- W4310713029 cites W1996273492 @default.
- W4310713029 cites W1997201508 @default.
- W4310713029 cites W2004297512 @default.
- W4310713029 cites W2008174671 @default.
- W4310713029 cites W2016245451 @default.
- W4310713029 cites W2017398488 @default.
- W4310713029 cites W2036452223 @default.
- W4310713029 cites W2038951993 @default.
- W4310713029 cites W2046366955 @default.
- W4310713029 cites W2051986741 @default.
- W4310713029 cites W2056273160 @default.
- W4310713029 cites W2059205366 @default.
- W4310713029 cites W2059233219 @default.
- W4310713029 cites W2063032883 @default.
- W4310713029 cites W2063491361 @default.
- W4310713029 cites W2067261086 @default.
- W4310713029 cites W2070253543 @default.
- W4310713029 cites W2072446923 @default.
- W4310713029 cites W2085925082 @default.
- W4310713029 cites W2103607851 @default.
- W4310713029 cites W2107824712 @default.
- W4310713029 cites W2122153254 @default.
- W4310713029 cites W2132454074 @default.
- W4310713029 cites W2170600611 @default.
- W4310713029 cites W2325339364 @default.
- W4310713029 cites W2339062229 @default.
- W4310713029 cites W2409156025 @default.
- W4310713029 cites W2478427153 @default.
- W4310713029 cites W2550830181 @default.
- W4310713029 cites W2589180713 @default.
- W4310713029 cites W2614729403 @default.
- W4310713029 cites W2759786464 @default.
- W4310713029 cites W2765924843 @default.
- W4310713029 cites W2784019049 @default.
- W4310713029 cites W2794655937 @default.
- W4310713029 cites W2803453985 @default.
- W4310713029 cites W2909634746 @default.
- W4310713029 cites W2913645272 @default.
- W4310713029 cites W2941344629 @default.
- W4310713029 cites W2946632069 @default.
- W4310713029 cites W2955414425 @default.
- W4310713029 cites W2972188383 @default.
- W4310713029 cites W3016913398 @default.
- W4310713029 cites W3027891475 @default.
- W4310713029 cites W3037696853 @default.
- W4310713029 cites W3047932790 @default.
- W4310713029 cites W3155273679 @default.
- W4310713029 cites W4206713877 @default.
- W4310713029 cites W4225526049 @default.
- W4310713029 cites W4243225672 @default.
- W4310713029 cites W830675808 @default.
- W4310713029 doi "https://doi.org/10.1016/j.jinorgbio.2022.112092" @default.
- W4310713029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36549168" @default.
- W4310713029 hasPublicationYear "2023" @default.
- W4310713029 type Work @default.
- W4310713029 citedByCount "0" @default.
- W4310713029 crossrefType "journal-article" @default.
- W4310713029 hasAuthorship W4310713029A5012075948 @default.
- W4310713029 hasAuthorship W4310713029A5012803164 @default.
- W4310713029 hasAuthorship W4310713029A5013092722 @default.
- W4310713029 hasAuthorship W4310713029A5023660955 @default.
- W4310713029 hasAuthorship W4310713029A5031516890 @default.
- W4310713029 hasAuthorship W4310713029A5064019950 @default.
- W4310713029 hasAuthorship W4310713029A5081285582 @default.
- W4310713029 hasConcept C116569031 @default.
- W4310713029 hasConcept C121332964 @default.
- W4310713029 hasConcept C13965031 @default.
- W4310713029 hasConcept C155647269 @default.
- W4310713029 hasConcept C161790260 @default.
- W4310713029 hasConcept C170493617 @default.
- W4310713029 hasConcept C178790620 @default.
- W4310713029 hasConcept C179104552 @default.
- W4310713029 hasConcept C185592680 @default.
- W4310713029 hasConcept C187961010 @default.
- W4310713029 hasConcept C21774173 @default.
- W4310713029 hasConcept C29730261 @default.
- W4310713029 hasConcept C46141821 @default.
- W4310713029 hasConcept C505216180 @default.
- W4310713029 hasConcept C55493867 @default.