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- W4310721586 abstract "<h2>Abstract</h2> Over the past seven years, hundreds of cases have been processed with the goal of phenotyping, biogeographical ancestry, and/or forensic genetic genealogy (FGG) research. However, not all profiles developed were suitable for upload to public databases or for phenotype and ancestry estimations, while some poor-quality samples surprisingly were. The capabilities for FGG testing have grown in the past year and are still improving. This summary will serve to compare the results that can be expected from three very different DNA profiling systems; single nucleotide polymorphism (SNP) array, whole genome sequencing (WGS), and targeted SNP testing via next generation sequencing (NGS). The ability of these testing methods to handle varying sample types, degradation, inhibition, the presence of non-human DNA, and low quantities of DNA will be examined. The information gained over the past seven years and hundreds of samples later can inform the decision-making processes moving forward as the field of FGG continues to grow. This summary will conclude by highlighting a successful case with a challenged sample processed with the intention of forensic genetic genealogy research." @default.
- W4310721586 created "2022-12-16" @default.
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- W4310721586 date "2022-12-01" @default.
- W4310721586 modified "2023-09-25" @default.
- W4310721586 title "Seven years of SNPs: An assessment of methods utilized for generating profiles for forensic genetic genealogy" @default.
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- W4310721586 doi "https://doi.org/10.1016/j.fsigss.2022.11.002" @default.
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