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- W4310727100 abstract "A highly efficient and straightforward synthetic protocol for the synthesis of 2-benzyl-3-arylquinoline derivatives is developed from aryl amines and styrene oxides in the presence of 20 mol% p-toluenesulfonic acids under metal- and solvent-free conditions by employing a pseudo-three-component reaction. Using similar reaction conditions, the synthesis of 2,3-dialkylquinoline derivative can also be accomplished using aliphatic epoxide. The methodology has several advantages such as ease to handle, a broad substrate scope, good yields, metal- and solvent-free reaction conditions, and the formation of one CN and two CC bonds in a single step." @default.
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- W4310727100 date "2023-01-01" @default.
- W4310727100 modified "2023-09-26" @default.
- W4310727100 title "Metal- and solvent-free synthesis of 2-benzyl-3-arylquinoline using a pseudo-three-component reaction" @default.
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- W4310727100 doi "https://doi.org/10.1016/j.tetlet.2022.154283" @default.
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