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- W4310753453 abstract "Bladder cancer with HER2 high expression is related to pathological malignancy and poor prognosis. The standard care for muscle-invasive bladder cancer (MIBC) is neoadjuvant chemotherapy (NAC) followed by radical cystectomy. For HER2 positive MIBC, the efficacy of cisplatin- based NAC are unsatisfied. This study aims to evaluate the safety and efficacy of RC48-ADC, an anti-HER2 antibody conjugation, and tislelizumab as a novel neoadjuvant treatment in this population." @default.
- W4310753453 created "2022-12-17" @default.
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- W4310753453 date "2022-11-01" @default.
- W4310753453 modified "2023-09-27" @default.
- W4310753453 title "135O A multi-center phase Ib/II study of RC48-ADC combined with tislelizumab as neoadjuvant treatment in patients with HER2 positive locally advanced MIBC" @default.
- W4310753453 doi "https://doi.org/10.1016/j.annonc.2022.10.170" @default.
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