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- W4310817581 abstract "Schizophrenia (SCZ) and obsessive-compulsive disorder (OCD) are complex polygenic disorders with brain morphology abnormalities. The etiologies and relationship of both disorders remain elusive, and should be further investigated. Thus, induced pluripotent stem cells (iPSCs) were generated from peripheral blood mononuclear cells (PBMCs) from an OCD patient, his mother with SCZ and his healthy father with reprograming method. All iPSCs were characterized to have normal karyotype and expression of pluripotency makers. These iPSCs will be a valuable model to elucidate the pathophysiological mechanisms and association of both diseases." @default.
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- W4310817581 date "2023-02-01" @default.
- W4310817581 modified "2023-09-30" @default.
- W4310817581 title "Generation and characterization of iPSCs from a patient with obsessive–compulsive disorder, his mother with schizophrenia and his healthy father" @default.
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- W4310817581 doi "https://doi.org/10.1016/j.scr.2022.102993" @default.
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