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- W4310842070 abstract "The chromosome 1p/19q co-deletion which is a hallmark of oligodendroglioma plays more crucial role in glioma classification especially in “The 2021 WHO Classification of Tumors of the Central Nervous System”. A more effective non-invasive method to distinguish 1p/19q co-deletion tumor from all gliomas can facilitate the strategy selection of pathologists, physicians, and surgeons. Preoperative MRI, including T1, T2, enhanced T1 and T2-FLAIR, from 61 glioma patients of our facility were reviewed. Data from 89 gliomas subjects from The Cancer Imaging Archive were recruited. Following the preprocessing, we improved the U-net and ResNet152 based on the MRI data of different modalities to determine the 1p/19q codeletion from overall gliomas. The different models were compared. The UMAP result implies that two different data share some similar traits. All the sensitivity, specificity and accuracy of U-net are higher than that of the ResNet152. The test accuracy with four modalities outperforms others significantly, reaching 92.156%. We introduce an efficient pipeline with U-net network for the identification of 1p/19q genotype status. The study implements one step judgement with multi-modal sequence MRI images. It takes a further step to suggest that machine learning can render more possibilities to conventional MRI." @default.
- W4310842070 created "2022-12-19" @default.
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- W4310842070 date "2023-01-01" @default.
- W4310842070 modified "2023-10-18" @default.
- W4310842070 title "Automatic 1p/19q co-deletion identification of gliomas by MRI using deep learning U-net network" @default.
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- W4310842070 doi "https://doi.org/10.1016/j.compeleceng.2022.108482" @default.
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