Matches in SemOpenAlex for { <https://semopenalex.org/work/W4310856857> ?p ?o ?g. }
- W4310856857 endingPage "109492" @default.
- W4310856857 startingPage "109492" @default.
- W4310856857 abstract "The current experiment aimed to identify the possible protective role of rivastigmine (RIVA) in gentamicin (GNT)-induced acute kidney injury (AKI) in rats. RIVA was administered in the presence and absence of GNT. Kidney function markers and serum and renal GNT concentrations were measured. Renal oxidative stress parameters as well as inflammatory and apoptotic biomarkers were evaluated. Renal histopathological assessment and nuclear factor kappa-B (NF-κB) immunohistochemical study were performed. GNT administration increased serum creatinine, urea, and cystatin C concentrations. RIVA ameliorated these changes via mitigating GNT-induced increases of renal oxidative stress, inflammation, and apoptotic parameters. RIVA showed a prompt improvement in the histopathological renal damage and a decrease in NF-κB immunoexpression. In conclusion, RIVA protective effects against GNT-induced AKI are mediated by decreasing GNT concentration in renal tissue and other effects like antioxidant and antiapoptotic effects possibly through its cholinergic anti-inflammatory action." @default.
- W4310856857 created "2022-12-19" @default.
- W4310856857 creator A5018451775 @default.
- W4310856857 creator A5026587615 @default.
- W4310856857 creator A5059303055 @default.
- W4310856857 creator A5059991237 @default.
- W4310856857 creator A5073536869 @default.
- W4310856857 creator A5089573796 @default.
- W4310856857 date "2023-01-01" @default.
- W4310856857 modified "2023-09-23" @default.
- W4310856857 title "Rivastigmine ameliorates gentamicin experimentally induced acute renal toxicity" @default.
- W4310856857 cites W1590457525 @default.
- W4310856857 cites W1971774538 @default.
- W4310856857 cites W2015746497 @default.
- W4310856857 cites W2030032466 @default.
- W4310856857 cites W2031076750 @default.
- W4310856857 cites W2033620247 @default.
- W4310856857 cites W2034090364 @default.
- W4310856857 cites W2055376538 @default.
- W4310856857 cites W2056202951 @default.
- W4310856857 cites W2066982256 @default.
- W4310856857 cites W2069132215 @default.
- W4310856857 cites W2070549269 @default.
- W4310856857 cites W2075073532 @default.
- W4310856857 cites W2080669591 @default.
- W4310856857 cites W2093431501 @default.
- W4310856857 cites W211760076 @default.
- W4310856857 cites W2157530259 @default.
- W4310856857 cites W2164082764 @default.
- W4310856857 cites W2168809448 @default.
- W4310856857 cites W2180251805 @default.
- W4310856857 cites W2580790931 @default.
- W4310856857 cites W2603592129 @default.
- W4310856857 cites W2772412764 @default.
- W4310856857 cites W2789145452 @default.
- W4310856857 cites W2801275455 @default.
- W4310856857 cites W2846457755 @default.
- W4310856857 cites W2892506986 @default.
- W4310856857 cites W2902628420 @default.
- W4310856857 cites W2961832091 @default.
- W4310856857 cites W3021312498 @default.
- W4310856857 cites W3092484518 @default.
- W4310856857 cites W3134890250 @default.
- W4310856857 cites W3135167022 @default.
- W4310856857 cites W3184731605 @default.
- W4310856857 cites W4206116723 @default.
- W4310856857 cites W4212945044 @default.
- W4310856857 cites W4282972019 @default.
- W4310856857 doi "https://doi.org/10.1016/j.intimp.2022.109492" @default.
- W4310856857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36459920" @default.
- W4310856857 hasPublicationYear "2023" @default.
- W4310856857 type Work @default.
- W4310856857 citedByCount "1" @default.
- W4310856857 countsByYear W43108568572023 @default.
- W4310856857 crossrefType "journal-article" @default.
- W4310856857 hasAuthorship W4310856857A5018451775 @default.
- W4310856857 hasAuthorship W4310856857A5026587615 @default.
- W4310856857 hasAuthorship W4310856857A5059303055 @default.
- W4310856857 hasAuthorship W4310856857A5059991237 @default.
- W4310856857 hasAuthorship W4310856857A5073536869 @default.
- W4310856857 hasAuthorship W4310856857A5089573796 @default.
- W4310856857 hasConcept C126189478 @default.
- W4310856857 hasConcept C126322002 @default.
- W4310856857 hasConcept C159641895 @default.
- W4310856857 hasConcept C2776151105 @default.
- W4310856857 hasConcept C2776914184 @default.
- W4310856857 hasConcept C2779548226 @default.
- W4310856857 hasConcept C2780091579 @default.
- W4310856857 hasConcept C2780306776 @default.
- W4310856857 hasConcept C29730261 @default.
- W4310856857 hasConcept C71924100 @default.
- W4310856857 hasConcept C98274493 @default.
- W4310856857 hasConceptScore W4310856857C126189478 @default.
- W4310856857 hasConceptScore W4310856857C126322002 @default.
- W4310856857 hasConceptScore W4310856857C159641895 @default.
- W4310856857 hasConceptScore W4310856857C2776151105 @default.
- W4310856857 hasConceptScore W4310856857C2776914184 @default.
- W4310856857 hasConceptScore W4310856857C2779548226 @default.
- W4310856857 hasConceptScore W4310856857C2780091579 @default.
- W4310856857 hasConceptScore W4310856857C2780306776 @default.
- W4310856857 hasConceptScore W4310856857C29730261 @default.
- W4310856857 hasConceptScore W4310856857C71924100 @default.
- W4310856857 hasConceptScore W4310856857C98274493 @default.
- W4310856857 hasLocation W43108568571 @default.
- W4310856857 hasLocation W43108568572 @default.
- W4310856857 hasOpenAccess W4310856857 @default.
- W4310856857 hasPrimaryLocation W43108568571 @default.
- W4310856857 hasRelatedWork W1934515323 @default.
- W4310856857 hasRelatedWork W1975612397 @default.
- W4310856857 hasRelatedWork W2018263823 @default.
- W4310856857 hasRelatedWork W2106188053 @default.
- W4310856857 hasRelatedWork W2146459370 @default.
- W4310856857 hasRelatedWork W2323779611 @default.
- W4310856857 hasRelatedWork W2377952855 @default.
- W4310856857 hasRelatedWork W2887444466 @default.
- W4310856857 hasRelatedWork W2903842133 @default.
- W4310856857 hasRelatedWork W3152378732 @default.
- W4310856857 hasVolume "114" @default.