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- W4310903669 abstract "Liver cirrhosis is the 11th most common cause of death, causing more than 1 million deaths globally each year, and together with liver cancer, it accounts for 3.5% of all deaths worldwide.[1] Cirrhosis develops due to long-term chronic liver inflammation, with the replacement of healthy liver parenchyma with diffuse liver fibrosis and regenerative nodules, leading to portal hypertension and various complications and even hepatocellular carcinoma.[2] [3] [4] The management of cirrhosis is mainly based on the treatment of cause and complications including comprehensive supportive care. However, there are currently no effective drug therapies to cure the disease, and liver transplantation remains the gold standard treatment for cirrhosis.[5] [6] Given that cirrhosis has brought heavy health and economic burden to many countries, there is an urgent need for in-depth study of the pathogenesis and key factors of cirrhosis to find feasible intervention strategies." @default.
- W4310903669 created "2022-12-20" @default.
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- W4310903669 date "2022-12-01" @default.
- W4310903669 modified "2023-09-23" @default.
- W4310903669 title "Discovery of FOCAD: An Important Gene in Liver Cirrhosis" @default.
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- W4310903669 doi "https://doi.org/10.1055/s-0042-1758351" @default.
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