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- W4310943939 endingPage "26" @default.
- W4310943939 startingPage "12" @default.
- W4310943939 abstract "Abstract The fifth edition of the World Health Organization classification of soft tissue and bone tumors redefined Ewing sarcoma by fusions between EWSR1 / FUS and ETS family of transcription factors, and recognized three tumor groups among Ewing‐like sarcoma: CIC ‐rearranged sarcoma, sarcoma with BCOR genetic alterations, and round cell sarcoma with EWSR1 ::non‐ETS fusions. Although this classification underscores the critical role of molecular genetics in the diagnosis of small round cell sarcoma, each entry is recognized as a specific entity not only because they have different genetics but because their phenotypes are distinct and reasonably robust to support the diagnosis. This review focuses on the morphological aspects of Ewing sarcoma and a subset of Ewing‐like sarcomas ( CIC ‐rearranged sarcoma, BCOR ‐associated sarcoma, and EWSR1::NFATC2 sarcoma) for which phenotypic characteristics have been well established. Classic histological findings, uncommon variations, and recurrent diagnostic pitfalls are addressed, along with the utility of recently developed immunohistochemical markers (NKX2.2, PAX7, ETV4, BCOR, CCNB3, and NKX3.1). Phenotypic expertise would significantly expedite the diagnostic process and complement (or sometimes outperform) genetic testing, even in well‐resourced settings. Morphological knowledge plays an even more substantial role in facilities that do not have easy access to molecular testing." @default.
- W4310943939 created "2022-12-21" @default.
- W4310943939 creator A5006840327 @default.
- W4310943939 date "2022-12-09" @default.
- W4310943939 modified "2023-10-15" @default.
- W4310943939 title "Ewing and Ewing‐like sarcomas: A morphological guide through genetically‐defined entities" @default.
- W4310943939 cites W1907011253 @default.
- W4310943939 cites W1933020950 @default.
- W4310943939 cites W1975832045 @default.
- W4310943939 cites W1975919183 @default.
- W4310943939 cites W1976862232 @default.
- W4310943939 cites W1983529894 @default.
- W4310943939 cites W2014400481 @default.
- W4310943939 cites W2015025893 @default.
- W4310943939 cites W2019038560 @default.
- W4310943939 cites W2030536448 @default.
- W4310943939 cites W2035558442 @default.
- W4310943939 cites W2038819795 @default.
- W4310943939 cites W2053924227 @default.
- W4310943939 cites W2064352301 @default.
- W4310943939 cites W2068723977 @default.
- W4310943939 cites W2083685172 @default.
- W4310943939 cites W2088152579 @default.
- W4310943939 cites W2096113686 @default.
- W4310943939 cites W2096573869 @default.
- W4310943939 cites W2131385589 @default.
- W4310943939 cites W2136522034 @default.
- W4310943939 cites W2198646997 @default.
- W4310943939 cites W2209758350 @default.
- W4310943939 cites W2253637172 @default.
- W4310943939 cites W2286322195 @default.
- W4310943939 cites W2320347523 @default.
- W4310943939 cites W2322477070 @default.
- W4310943939 cites W2327499138 @default.
- W4310943939 cites W2330348207 @default.
- W4310943939 cites W2340944150 @default.
- W4310943939 cites W2408462286 @default.
- W4310943939 cites W2415443351 @default.
- W4310943939 cites W2474681590 @default.
- W4310943939 cites W2478430570 @default.
- W4310943939 cites W2514636791 @default.
- W4310943939 cites W2517713921 @default.
- W4310943939 cites W2551196929 @default.
- W4310943939 cites W2587324003 @default.
- W4310943939 cites W2588086860 @default.
- W4310943939 cites W2590549347 @default.
- W4310943939 cites W2603912459 @default.
- W4310943939 cites W2612857382 @default.
- W4310943939 cites W2671119825 @default.
- W4310943939 cites W2747947852 @default.
- W4310943939 cites W2749415478 @default.
- W4310943939 cites W2753091713 @default.
- W4310943939 cites W2766564047 @default.
- W4310943939 cites W2772138647 @default.
- W4310943939 cites W2772231957 @default.
- W4310943939 cites W2773699915 @default.
- W4310943939 cites W2775575362 @default.
- W4310943939 cites W2789960601 @default.
- W4310943939 cites W2791740968 @default.
- W4310943939 cites W2808998977 @default.
- W4310943939 cites W2898884463 @default.
- W4310943939 cites W2899627911 @default.
- W4310943939 cites W2922436326 @default.
- W4310943939 cites W2938922246 @default.
- W4310943939 cites W2944609925 @default.
- W4310943939 cites W2949584415 @default.
- W4310943939 cites W2981355604 @default.
- W4310943939 cites W2996274411 @default.
- W4310943939 cites W2997388654 @default.
- W4310943939 cites W2999154761 @default.
- W4310943939 cites W2999863489 @default.
- W4310943939 cites W3004860042 @default.
- W4310943939 cites W3020668427 @default.
- W4310943939 cites W3036355245 @default.
- W4310943939 cites W3037318461 @default.
- W4310943939 cites W3042157678 @default.
- W4310943939 cites W3084001665 @default.
- W4310943939 cites W3089007636 @default.
- W4310943939 cites W3091084435 @default.
- W4310943939 cites W3097296541 @default.
- W4310943939 cites W3112633699 @default.
- W4310943939 cites W3118486034 @default.
- W4310943939 cites W3128848240 @default.
- W4310943939 cites W3135572089 @default.
- W4310943939 cites W3164143540 @default.
- W4310943939 cites W3164363354 @default.
- W4310943939 cites W3168388669 @default.
- W4310943939 cites W3174191395 @default.
- W4310943939 cites W4205325026 @default.
- W4310943939 cites W4206109991 @default.
- W4310943939 cites W4224270775 @default.
- W4310943939 cites W4229048214 @default.
- W4310943939 cites W4283074758 @default.
- W4310943939 cites W4285389637 @default.
- W4310943939 cites W4286501641 @default.
- W4310943939 cites W4310943939 @default.
- W4310943939 cites W85780338 @default.
- W4310943939 cites W88833640 @default.