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• W4311005131 abstract "Neuropathic pain in multiple sclerosis is a common phenomenon and is accompanied by numerous negative consequences, which significantly reduces their quality of life and increases the degree of disability. The purpose of this study is to study the factors that act as predictors of neuropathic pain in patients with multiple sclerosis. Were involved in the research process. 321 patients with multiple sclerosis - 110 men (34.3%) and 211 women (65.7%), aged 21 to 55 years. Among the characteristics of multiple sclerosis, the age of the patient when diagnosed, the duration of the disease, the type of course, and the total assessment of neurological deficit were determined. Appropriate scales were used to determine the type and duration of pain, socio-demographic, psychopathological, statistical research methods and comorbid pathology was taken into account. It was established that female gender is a predictor of central dysesthesias in neuropathic pain - 2.61 (1.06-6.42; p=0.04). It was also found that the factors of dysesthesias of central origin are subclinical anxiety disorders - 2.66 (1.19-5.92; p=0.02) and subclinical depressive disorders - 2.92 (1.31-6.49; p=0.02). p=0.01). Predictors of dysesthesias of central genesis are an increase in the duration of multiple sclerosis for each subsequent year - 1.07 (1.02-1.14; p=0.01), progressive type of multiple sclerosis - 5.78 (2.45-13.59; p= 0.001) and an increase in Expanded Disability Status Scale indicators for each subsequent 0.5 points – 1.03 (1.01-1.06; p=0.01). Early, correction of subclinical anxiety and depressive disorders as predictors of modifiable central neuropathic pain is likely for adequate management of neuropathic pain in multiple sclerosis. Patients with advanced type of multiple sclerosis, especially those with a high score on the Expanded Disability Status Scale are a group at increased risk of central neuropathic pain and, accordingly, require more careful monitoring with the aim of early detection and correction of dysesthesias, which will positively affect the quality of life of patients. Patients with progressive type of multiple sclerosis, especially those with a high score on the Expanded Disability Status Scale are a group at increased risk of central neuropathic pain and, accordingly, require more careful monitoring with the aim of early detection and correction of dysesthesias, which will positively affect the quality of life of patients." @default.
• W4311005131 created "2022-12-22" @default.
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• W4311005131 date "2022-11-29" @default.
• W4311005131 modified "2023-10-01" @default.
• W4311005131 title "PREDICTORS OF NEUROPATHIC PAIN IN PATIENTS WITH MULTIPLE SCLEROSIS (CROSS-SECTIONAL STUDY)" @default.
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• W4311005131 doi "https://doi.org/10.31718/2077-1096.22.3.4.47" @default.
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