Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311025350> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4311025350 endingPage "6999" @default.
- W4311025350 startingPage "6985" @default.
- W4311025350 abstract "Choosing patients with HIV/AIDS (PLWH) with virologic failure observed in the course of treatment, and analyzing the CD4(+) T cell count of PLWH with different subtypes of virus and the risk factors of CD4 (+) T cell count recovery.Analyze and evaluate the change of median CD4(+) T cell count of PLWH infected with different HIV-1 subtypes in Sichuan Province after treatment by rank sum test. Univariate and multivariate logistic regression models were used to analyze the risk factors on CD4(+) T cell count growth after PLWH treatment.A total of 4977 cases were analysed, including CRF07_BC 2358 cases (47.38%), CRF01_AE 1507 cases (30.28%), CRF08_BC 577 cases (11.59%), CRF85_BC 303 cases (6.09%) and other subtypes 232 cases (4.66%). PLWH infected with CRF85_BC had lower median CD4(+) T cell count after treatment (p < 0.05). It was found that protective factors to increase CD4(+) T cell count (p < 0.05) including females, Yi people, married or cohabiting, educational level at primary school or above, initial and recent treatment with Tenofovir + Lamivudine + Nevirapine Wellen, the second-line regimen with lopinavir/ritonavir (LPV/r) and the treatment time is more than 24 months. However, over 50 years old, the disease course is in AIDS stage, the infection of CRF01_AE and CRF85_BC virus was the risk factor on CD4(+) T cell count increase (p < 0.05). PLWH with higher initial CD4 level had a lower ratio of CD4(+) T cell count increase (≥50 cells/μL) (p < 0.05).Age, sex, ethnicity, marriage, education, disease status, treatment protocols, treatment time, initial CD4(+) T cell count, and virus subtype are the influencing factors of PLWH CD4(+) T cell count increase. The poor recovery of CD4(+) T cell count after treatment was observed in PLWH infected with CRF85_BC virus." @default.
- W4311025350 created "2022-12-22" @default.
- W4311025350 creator A5005476467 @default.
- W4311025350 creator A5017756113 @default.
- W4311025350 creator A5019813887 @default.
- W4311025350 creator A5053963386 @default.
- W4311025350 creator A5063909163 @default.
- W4311025350 creator A5072861069 @default.
- W4311025350 creator A5080037612 @default.
- W4311025350 creator A5081153429 @default.
- W4311025350 creator A5086664284 @default.
- W4311025350 date "2022-12-01" @default.
- W4311025350 modified "2023-09-30" @default.
- W4311025350 title "CD4(+) T Cell Count Progress and Influencing Factors of Recovery in AIDS Patients with Virological Failure in Sichuan Province: A Retrospective Cohort Study" @default.
- W4311025350 cites W1612998399 @default.
- W4311025350 cites W1979434221 @default.
- W4311025350 cites W2089384420 @default.
- W4311025350 cites W2106164053 @default.
- W4311025350 cites W2113642360 @default.
- W4311025350 cites W2941777894 @default.
- W4311025350 cites W3017311299 @default.
- W4311025350 cites W3092883013 @default.
- W4311025350 cites W3096257835 @default.
- W4311025350 cites W3216859709 @default.
- W4311025350 cites W4225330548 @default.
- W4311025350 doi "https://doi.org/10.2147/idr.s378799" @default.
- W4311025350 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36478965" @default.
- W4311025350 hasPublicationYear "2022" @default.
- W4311025350 type Work @default.
- W4311025350 citedByCount "0" @default.
- W4311025350 crossrefType "journal-article" @default.
- W4311025350 hasAuthorship W4311025350A5005476467 @default.
- W4311025350 hasAuthorship W4311025350A5017756113 @default.
- W4311025350 hasAuthorship W4311025350A5019813887 @default.
- W4311025350 hasAuthorship W4311025350A5053963386 @default.
- W4311025350 hasAuthorship W4311025350A5063909163 @default.
- W4311025350 hasAuthorship W4311025350A5072861069 @default.
- W4311025350 hasAuthorship W4311025350A5080037612 @default.
- W4311025350 hasAuthorship W4311025350A5081153429 @default.
- W4311025350 hasAuthorship W4311025350A5086664284 @default.
- W4311025350 hasBestOaLocation W43110253501 @default.
- W4311025350 hasConcept C126322002 @default.
- W4311025350 hasConcept C142462285 @default.
- W4311025350 hasConcept C151956035 @default.
- W4311025350 hasConcept C203014093 @default.
- W4311025350 hasConcept C2777182164 @default.
- W4311025350 hasConcept C2779130552 @default.
- W4311025350 hasConcept C2779298103 @default.
- W4311025350 hasConcept C2781413609 @default.
- W4311025350 hasConcept C2993143319 @default.
- W4311025350 hasConcept C3013748606 @default.
- W4311025350 hasConcept C71924100 @default.
- W4311025350 hasConcept C72563966 @default.
- W4311025350 hasConcept C90924648 @default.
- W4311025350 hasConceptScore W4311025350C126322002 @default.
- W4311025350 hasConceptScore W4311025350C142462285 @default.
- W4311025350 hasConceptScore W4311025350C151956035 @default.
- W4311025350 hasConceptScore W4311025350C203014093 @default.
- W4311025350 hasConceptScore W4311025350C2777182164 @default.
- W4311025350 hasConceptScore W4311025350C2779130552 @default.
- W4311025350 hasConceptScore W4311025350C2779298103 @default.
- W4311025350 hasConceptScore W4311025350C2781413609 @default.
- W4311025350 hasConceptScore W4311025350C2993143319 @default.
- W4311025350 hasConceptScore W4311025350C3013748606 @default.
- W4311025350 hasConceptScore W4311025350C71924100 @default.
- W4311025350 hasConceptScore W4311025350C72563966 @default.
- W4311025350 hasConceptScore W4311025350C90924648 @default.
- W4311025350 hasLocation W43110253501 @default.
- W4311025350 hasLocation W43110253502 @default.
- W4311025350 hasLocation W43110253503 @default.
- W4311025350 hasOpenAccess W4311025350 @default.
- W4311025350 hasPrimaryLocation W43110253501 @default.
- W4311025350 hasRelatedWork W1989924554 @default.
- W4311025350 hasRelatedWork W2051976738 @default.
- W4311025350 hasRelatedWork W2108000358 @default.
- W4311025350 hasRelatedWork W2113921871 @default.
- W4311025350 hasRelatedWork W2124330138 @default.
- W4311025350 hasRelatedWork W2129845127 @default.
- W4311025350 hasRelatedWork W2132535766 @default.
- W4311025350 hasRelatedWork W2317464954 @default.
- W4311025350 hasRelatedWork W2611234483 @default.
- W4311025350 hasRelatedWork W4232639816 @default.
- W4311025350 hasVolume "Volume 15" @default.
- W4311025350 isParatext "false" @default.
- W4311025350 isRetracted "false" @default.
- W4311025350 workType "article" @default.