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• W4311043549 abstract "Using the CHA2DS2-VASc score to recognize the risk of stroke in patients with atrial fibrillation has been well-established. However, few studies have assessed whether the CHA2DS2-VASc score has a similar predictive value in recurrence after myocardial infarction (MI).We conducted a retrospective observational cohort study of adult inpatients with MI. The CHA2DS2-VASc and modified CHA2DS2-VASc (MCHA2DS2-VASc) scores of all patients were calculated. The associations of both scores with recurrent MI were analyzed.A total of 6,700 patients with MI (60.0 ± 11.1 years, 77.2% men) were enrolled, and 759 (11.3%) presented a definite recurrence during hospitalization. After multivariable adjustment by logistic regression in patients with MI, the CHA2DS2-VASc and MCHA2DS2-VASc scores were independently associated with recurrence. The MCHA2DS2-VASc score showed a better predictive value for risk of recurrence than that of CHA2DS2-VASc in overall [area under the receiver operating characteristic curve (AUC) 0.757 vs. 0.676] or male patients (AUC 0.759 vs. 0.708). MCHA2DS2-VASc was superior to CHA2DS2-VASc for identifying truly high-risk patients with MI, regardless of overall patients or sex-specific subgroups. The two scores had a similar focus on the identification of low-risk patients in overall or women, but not in men.The CHA2DS2-VASc and MCHA2DS2-VASc scores for predicting recurrence are validated in patients with MI. However, MCHA2DS2-VASc could be more helpful to secondary prevention than CHA2DS2-VASc after MI, especially in men. The superiority of MCHA2DS2-VASc compared with CHA2DS2-VASc in women is just more discriminatory for truly high-risk patients." @default.
• W4311043549 created "2022-12-23" @default.
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• W4311043549 date "2022-12-01" @default.
• W4311043549 modified "2023-10-03" @default.
• W4311043549 title "CHA2DS2-VASc score for in-hospital recurrence risk stratification in patients with myocardial infarction" @default.
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• W4311043549 doi "https://doi.org/10.3389/fcvm.2022.925932" @default.
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• W4311043549 hasPublicationYear "2022" @default.
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