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- W4311090908 endingPage "188844" @default.
- W4311090908 startingPage "188844" @default.
- W4311090908 abstract "The prevalence of obesity, diabetes mellitus (DM), and pancreatic cancer (PC) has been consistently increasing in the last two decades worldwide. Sharing various influential risk factors in genetics and environmental inducers in pathogenesis, the close correlations of these three diseases have been demonstrated in plenty of clinical studies using multiple parameters among different populations. On the contrary, most measures aimed to manage and treat obesity and DM effectively reduce the risk and prevent PC occurrence, yet certain drugs can inversely promote pancreatic carcinogenesis instead. Most importantly, an elevation of blood glucose with or without a reduction in body weight, along with other potential tools, may provide valuable clues for detecting PC at an early stage in patients with obesity and DM, favoring a timely intervention and prolonging survival. Herein, the epidemiological and etiological correlations among these three diseases and the supporting clinical evidence of their connections are first summarized to favor a better and more thorough understanding of obesity- and DM-related pancreatic carcinogenesis. After comparing the distinct impacts of different weight-lowering and anti-diabetic treatments on the risk of PC, the possible diagnostic implications of hyperglycemia and weight loss in PC screening are also addressed in detail." @default.
- W4311090908 created "2022-12-23" @default.
- W4311090908 creator A5009683743 @default.
- W4311090908 creator A5026838652 @default.
- W4311090908 creator A5045392886 @default.
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- W4311090908 creator A5052134746 @default.
- W4311090908 creator A5067680016 @default.
- W4311090908 creator A5082815201 @default.
- W4311090908 date "2023-01-01" @default.
- W4311090908 modified "2023-09-30" @default.
- W4311090908 title "Obesity, diabetes mellitus, and pancreatic carcinogenesis: Correlations, prevention, and diagnostic implications" @default.
- W4311090908 cites W1493806409 @default.
- W4311090908 cites W1508545440 @default.
- W4311090908 cites W1797357350 @default.
- W4311090908 cites W1841339625 @default.
- W4311090908 cites W1882801942 @default.
- W4311090908 cites W1901810038 @default.
- W4311090908 cites W1945583225 @default.
- W4311090908 cites W1964095236 @default.
- W4311090908 cites W1968905630 @default.
- W4311090908 cites W1973887803 @default.
- W4311090908 cites W1974472988 @default.
- W4311090908 cites W1975751431 @default.
- W4311090908 cites W1981879068 @default.
- W4311090908 cites W1982814634 @default.
- W4311090908 cites W1984358237 @default.
- W4311090908 cites W1985369305 @default.
- W4311090908 cites W1987041848 @default.
- W4311090908 cites W1989915262 @default.
- W4311090908 cites W1992785592 @default.
- W4311090908 cites W1998608669 @default.
- W4311090908 cites W2004346418 @default.
- W4311090908 cites W2009679586 @default.
- W4311090908 cites W2010408200 @default.
- W4311090908 cites W2023632463 @default.
- W4311090908 cites W2025634024 @default.
- W4311090908 cites W2031848004 @default.
- W4311090908 cites W2041755595 @default.
- W4311090908 cites W2044486670 @default.
- W4311090908 cites W2046749198 @default.
- W4311090908 cites W2060541352 @default.
- W4311090908 cites W2061738696 @default.
- W4311090908 cites W2066089451 @default.
- W4311090908 cites W2066809635 @default.
- W4311090908 cites W2067786443 @default.
- W4311090908 cites W2074653757 @default.
- W4311090908 cites W2080832413 @default.
- W4311090908 cites W2086482784 @default.
- W4311090908 cites W2086664081 @default.
- W4311090908 cites W2090440324 @default.
- W4311090908 cites W2091054798 @default.
- W4311090908 cites W2093548963 @default.
- W4311090908 cites W2095695954 @default.
- W4311090908 cites W2096169676 @default.
- W4311090908 cites W2101880068 @default.
- W4311090908 cites W2104643926 @default.
- W4311090908 cites W2105524540 @default.
- W4311090908 cites W2106840901 @default.
- W4311090908 cites W2109027812 @default.
- W4311090908 cites W2109366467 @default.
- W4311090908 cites W2111552902 @default.
- W4311090908 cites W2112981414 @default.
- W4311090908 cites W2115931066 @default.
- W4311090908 cites W2116008558 @default.
- W4311090908 cites W2119184048 @default.
- W4311090908 cites W2119625192 @default.
- W4311090908 cites W2121141922 @default.
- W4311090908 cites W2122310415 @default.
- W4311090908 cites W2123978014 @default.
- W4311090908 cites W2125436438 @default.
- W4311090908 cites W2127527009 @default.
- W4311090908 cites W2131572295 @default.
- W4311090908 cites W2149569244 @default.
- W4311090908 cites W2155631120 @default.
- W4311090908 cites W2158379097 @default.
- W4311090908 cites W2158731007 @default.
- W4311090908 cites W2159946871 @default.
- W4311090908 cites W2160695284 @default.
- W4311090908 cites W2163531555 @default.
- W4311090908 cites W2163886829 @default.
- W4311090908 cites W2165987645 @default.
- W4311090908 cites W2168289036 @default.
- W4311090908 cites W2168705381 @default.
- W4311090908 cites W2169214947 @default.
- W4311090908 cites W2169783774 @default.
- W4311090908 cites W2169895148 @default.
- W4311090908 cites W2172292090 @default.
- W4311090908 cites W2172304980 @default.
- W4311090908 cites W2182964614 @default.
- W4311090908 cites W2200565967 @default.
- W4311090908 cites W2201919417 @default.
- W4311090908 cites W2216707663 @default.
- W4311090908 cites W2225179116 @default.
- W4311090908 cites W2238103902 @default.
- W4311090908 cites W2245299984 @default.
- W4311090908 cites W2288987572 @default.
- W4311090908 cites W2325892404 @default.