FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311127687> ?p ?o ?g. }

• W4311127687 endingPage "397" @default.
• W4311127687 startingPage "388" @default.
• W4311127687 abstract "Circulating concentration of insulin-like growth factor (IGF)-1 in patients with polycystic ovary syndrome (PCOS) is still unclear. Therefore, we aimed to investigate the association of IGF-1 with PCOS through this meta-analysis.Literature search was conducted through PubMed, Embase, Web of Science, Cochrane Library, and China National Knowledge Infrastructure (up to July 2022). A manual search was performed on the references of related original research. Then, we applied the random-effects model to evaluate the overall effect size by calculating the standard mean difference and its 95% CI. Subgroup analyses were used to explore the sources of heterogeneity. In addition, a sensitivity analysis was performed and publication bias was assessed.Twenty studies were included in this meta-analysis involving 657 individuals: 362 patients with PCOS and 295 normal controls. The results of meta-analysis showed that serum IGF-1 levels were significantly higher in patients with PCOS than in controls (standard mean difference, 0.89; 95% CI, 0.34-1.45; P = .002). The final pooled data were determined by the random-effects model because a significant high heterogeneity (I2 = 89%) was found. A subgroup analysis based on body mass index showed that elevated IGF-1 level was associated with normal-weight and overweight patients in the PCOS group, but there was no significant association with obesity. The sensitivity analysis indicated that no individual study significantly affected the overall pooled result and no publishing bias was observed.These data suggest that elevated serum IGF-1 levels may not be a major cause of PCOS pathogenesis. Body mass index may be a major determinant of serum IGF-1." @default.
• W4311127687 created "2022-12-23" @default.
• W4311127687 creator A5002884286 @default.
• W4311127687 creator A5011068248 @default.
• W4311127687 creator A5014839531 @default.
• W4311127687 creator A5038537038 @default.
• W4311127687 creator A5040629535 @default.
• W4311127687 creator A5055693358 @default.
• W4311127687 creator A5079011265 @default.
• W4311127687 date "2023-05-01" @default.
• W4311127687 modified "2023-09-24" @default.
• W4311127687 title "Association of Insulin-Like Growth Factor-1 With Polycystic Ovarian Syndrome: A Systematic Review and Meta-analysis" @default.
• W4311127687 cites W1577097214 @default.
• W4311127687 cites W1850464538 @default.
• W4311127687 cites W1872561883 @default.
• W4311127687 cites W1970586482 @default.
• W4311127687 cites W1975699654 @default.
• W4311127687 cites W1984067141 @default.
• W4311127687 cites W1985112859 @default.
• W4311127687 cites W2007230186 @default.
• W4311127687 cites W2037759924 @default.
• W4311127687 cites W2042497364 @default.
• W4311127687 cites W2045633069 @default.
• W4311127687 cites W2047490960 @default.
• W4311127687 cites W2054477503 @default.
• W4311127687 cites W2058401907 @default.
• W4311127687 cites W2065724312 @default.
• W4311127687 cites W2069178927 @default.
• W4311127687 cites W2076132119 @default.
• W4311127687 cites W2081028186 @default.
• W4311127687 cites W2091650619 @default.
• W4311127687 cites W2101189111 @default.
• W4311127687 cites W2102587217 @default.
• W4311127687 cites W2113329249 @default.
• W4311127687 cites W2116475791 @default.
• W4311127687 cites W2121489868 @default.
• W4311127687 cites W2129917396 @default.
• W4311127687 cites W2136050094 @default.
• W4311127687 cites W2166895358 @default.
• W4311127687 cites W2168569552 @default.
• W4311127687 cites W2168837754 @default.
• W4311127687 cites W2186218348 @default.
• W4311127687 cites W2407813863 @default.
• W4311127687 cites W2872633888 @default.
• W4311127687 cites W2992455868 @default.
• W4311127687 cites W3037440144 @default.
• W4311127687 cites W3118615836 @default.
• W4311127687 cites W3197252224 @default.
• W4311127687 cites W3201466718 @default.
• W4311127687 doi "https://doi.org/10.1016/j.eprac.2022.12.004" @default.
• W4311127687 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36516939" @default.
• W4311127687 hasPublicationYear "2023" @default.
• W4311127687 type Work @default.
• W4311127687 citedByCount "0" @default.
• W4311127687 crossrefType "journal-article" @default.
• W4311127687 hasAuthorship W4311127687A5002884286 @default.
• W4311127687 hasAuthorship W4311127687A5011068248 @default.
• W4311127687 hasAuthorship W4311127687A5014839531 @default.
• W4311127687 hasAuthorship W4311127687A5038537038 @default.
• W4311127687 hasAuthorship W4311127687A5040629535 @default.
• W4311127687 hasAuthorship W4311127687A5055693358 @default.
• W4311127687 hasAuthorship W4311127687A5079011265 @default.
• W4311127687 hasConcept C126322002 @default.
• W4311127687 hasConcept C134018914 @default.
• W4311127687 hasConcept C143781015 @default.
• W4311127687 hasConcept C168743327 @default.
• W4311127687 hasConcept C170493617 @default.
• W4311127687 hasConcept C187960798 @default.
• W4311127687 hasConcept C2775960820 @default.
• W4311127687 hasConcept C2776478404 @default.
• W4311127687 hasConcept C2777391703 @default.
• W4311127687 hasConcept C2780221984 @default.
• W4311127687 hasConcept C2780439572 @default.
• W4311127687 hasConcept C2780586474 @default.
• W4311127687 hasConcept C2780689927 @default.
• W4311127687 hasConcept C3018442814 @default.
• W4311127687 hasConcept C511355011 @default.
• W4311127687 hasConcept C71924100 @default.
• W4311127687 hasConcept C95190672 @default.
• W4311127687 hasConceptScore W4311127687C126322002 @default.
• W4311127687 hasConceptScore W4311127687C134018914 @default.
• W4311127687 hasConceptScore W4311127687C143781015 @default.
• W4311127687 hasConceptScore W4311127687C168743327 @default.
• W4311127687 hasConceptScore W4311127687C170493617 @default.
• W4311127687 hasConceptScore W4311127687C187960798 @default.
• W4311127687 hasConceptScore W4311127687C2775960820 @default.
• W4311127687 hasConceptScore W4311127687C2776478404 @default.
• W4311127687 hasConceptScore W4311127687C2777391703 @default.
• W4311127687 hasConceptScore W4311127687C2780221984 @default.
• W4311127687 hasConceptScore W4311127687C2780439572 @default.
• W4311127687 hasConceptScore W4311127687C2780586474 @default.
• W4311127687 hasConceptScore W4311127687C2780689927 @default.
• W4311127687 hasConceptScore W4311127687C3018442814 @default.
• W4311127687 hasConceptScore W4311127687C511355011 @default.
• W4311127687 hasConceptScore W4311127687C71924100 @default.
• W4311127687 hasConceptScore W4311127687C95190672 @default.
• W4311127687 hasIssue "5" @default.
• W4311127687 hasLocation W43111276871 @default.

• next