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- W4311145621 abstract "Five pairs of new racemic alkamides (1a/1b and 4a/4b-7a/7b) and two new achiral derivatives (2-3), as well as five known ones (8-12), were purified from the 95% EtOH extract of Zanthoxylum nitidum. Their structures were elucidated based on spectroscopic analyses (NMR and HR-ESI-MS), electronic circular dichroism (ECD) and NMR calculations. The enantiomeric separation was successfully achieved by chiral-phase HPLC-ECD measurements. Among all the isolates, compounds 2, 3, and 10 showed inhibitory effects against five human cancer cell lines, with IC50 values in range of 18.51-48.03 μM." @default.
- W4311145621 created "2022-12-23" @default.
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- W4311145621 date "2023-01-01" @default.
- W4311145621 modified "2023-09-27" @default.
- W4311145621 title "Structurally diverse isobutylamides from Zanthoxylum nitidum" @default.
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- W4311145621 doi "https://doi.org/10.1016/j.fitote.2022.105381" @default.
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