Matches in SemOpenAlex for { <https://semopenalex.org/work/W4311151928> ?p ?o ?g. }
- W4311151928 endingPage "2063" @default.
- W4311151928 startingPage "2063" @default.
- W4311151928 abstract "The host immune response to SARS-CoV-2 appears to play a critical role in disease pathogenesis and clinical manifestations in severe COVID-19 cases. Until now, the importance of developing a neutralizing antibody response in the acute phase and its relationship with progression to severe disease or fatal outcome among hospitalized patients remains unclear. In this study, we aim to characterize and compare longitudinally the primary humoral immune host response in the early stages of the disease, looking for an association between neutralization, antibody titers, infective viral lineage, and the clinical outcome in hospitalized and non-hospitalized patients. A total of 111 patients admitted at INER from November 2021 to June 2022 were included. We found that patients with negative or low neutralization showed a significant reduction in survival probability compared to patients with medium or high neutralization. We observed a significant decrease in the median of neutralization in patients infected with viral variants with changes in RBD of the spike protein. Our results suggest that developing an early and robust neutralizing response against SARS-CoV-2 may increase survival probability in critical patients." @default.
- W4311151928 created "2022-12-23" @default.
- W4311151928 creator A5006448915 @default.
- W4311151928 creator A5013842421 @default.
- W4311151928 creator A5020660752 @default.
- W4311151928 creator A5027709892 @default.
- W4311151928 creator A5031005224 @default.
- W4311151928 creator A5041652374 @default.
- W4311151928 creator A5049977752 @default.
- W4311151928 creator A5053970207 @default.
- W4311151928 creator A5056673886 @default.
- W4311151928 creator A5061577849 @default.
- W4311151928 creator A5076142203 @default.
- W4311151928 creator A5083547135 @default.
- W4311151928 creator A5083562535 @default.
- W4311151928 creator A5086496217 @default.
- W4311151928 date "2022-12-01" @default.
- W4311151928 modified "2023-10-16" @default.
- W4311151928 title "Longitudinal Characterization of a Neutralizing and Total Antibody Response in Patients with Severe COVID-19 and Fatal Outcomes" @default.
- W4311151928 cites W1874198475 @default.
- W4311151928 cites W2601704155 @default.
- W4311151928 cites W3008874180 @default.
- W4311151928 cites W3009885589 @default.
- W4311151928 cites W3009992310 @default.
- W4311151928 cites W3012756997 @default.
- W4311151928 cites W3013525829 @default.
- W4311151928 cites W3017510621 @default.
- W4311151928 cites W3020577244 @default.
- W4311151928 cites W3021590963 @default.
- W4311151928 cites W3027655857 @default.
- W4311151928 cites W3029126015 @default.
- W4311151928 cites W3033022675 @default.
- W4311151928 cites W3038265299 @default.
- W4311151928 cites W3041319886 @default.
- W4311151928 cites W3041654612 @default.
- W4311151928 cites W3041752529 @default.
- W4311151928 cites W3044660350 @default.
- W4311151928 cites W3045569863 @default.
- W4311151928 cites W3081916995 @default.
- W4311151928 cites W3086786425 @default.
- W4311151928 cites W3087505228 @default.
- W4311151928 cites W3092403777 @default.
- W4311151928 cites W3109969485 @default.
- W4311151928 cites W3110839708 @default.
- W4311151928 cites W3111459703 @default.
- W4311151928 cites W3113228067 @default.
- W4311151928 cites W3116211574 @default.
- W4311151928 cites W3127589090 @default.
- W4311151928 cites W3133757346 @default.
- W4311151928 cites W3163312867 @default.
- W4311151928 cites W3163785571 @default.
- W4311151928 cites W3165367963 @default.
- W4311151928 cites W3165479483 @default.
- W4311151928 cites W3180253783 @default.
- W4311151928 cites W3196287813 @default.
- W4311151928 cites W3199849883 @default.
- W4311151928 cites W3208059369 @default.
- W4311151928 cites W3215677756 @default.
- W4311151928 cites W4294767945 @default.
- W4311151928 doi "https://doi.org/10.3390/vaccines10122063" @default.
- W4311151928 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/36560474" @default.
- W4311151928 hasPublicationYear "2022" @default.
- W4311151928 type Work @default.
- W4311151928 citedByCount "0" @default.
- W4311151928 crossrefType "journal-article" @default.
- W4311151928 hasAuthorship W4311151928A5006448915 @default.
- W4311151928 hasAuthorship W4311151928A5013842421 @default.
- W4311151928 hasAuthorship W4311151928A5020660752 @default.
- W4311151928 hasAuthorship W4311151928A5027709892 @default.
- W4311151928 hasAuthorship W4311151928A5031005224 @default.
- W4311151928 hasAuthorship W4311151928A5041652374 @default.
- W4311151928 hasAuthorship W4311151928A5049977752 @default.
- W4311151928 hasAuthorship W4311151928A5053970207 @default.
- W4311151928 hasAuthorship W4311151928A5056673886 @default.
- W4311151928 hasAuthorship W4311151928A5061577849 @default.
- W4311151928 hasAuthorship W4311151928A5076142203 @default.
- W4311151928 hasAuthorship W4311151928A5083547135 @default.
- W4311151928 hasAuthorship W4311151928A5083562535 @default.
- W4311151928 hasAuthorship W4311151928A5086496217 @default.
- W4311151928 hasBestOaLocation W43111519281 @default.
- W4311151928 hasConcept C126322002 @default.
- W4311151928 hasConcept C14086860 @default.
- W4311151928 hasConcept C159047783 @default.
- W4311151928 hasConcept C159654299 @default.
- W4311151928 hasConcept C203014093 @default.
- W4311151928 hasConcept C22889606 @default.
- W4311151928 hasConcept C2779134260 @default.
- W4311151928 hasConcept C2779261636 @default.
- W4311151928 hasConcept C2780942790 @default.
- W4311151928 hasConcept C30036603 @default.
- W4311151928 hasConcept C3007834351 @default.
- W4311151928 hasConcept C3008058167 @default.
- W4311151928 hasConcept C32611913 @default.
- W4311151928 hasConcept C524204448 @default.
- W4311151928 hasConcept C71924100 @default.
- W4311151928 hasConcept C8891405 @default.
- W4311151928 hasConceptScore W4311151928C126322002 @default.
- W4311151928 hasConceptScore W4311151928C14086860 @default.